1
George T Walker: Strand displacement amplification. Becton Dickinson and Company, Donna R Fugit, October 3, 1995: US05455166 (371 worldwide citation)

This invention relates a nucleic acid target amplification and detection method which operates at a single temperature and makes use of a polymerase in conjunction with an endonuclease that will nick the polymerized strand such that the polymerase will displace the strand without digestion while gen ...


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Paul Yarin, Richard Fletcher, Joseph DiPisa, Glenn Philander Vonk: Systems and methods for monitoring patient compliance with medication regimens. Becton Dickinson and Company, Donna R Fugit, September 25, 2001: US06294999 (255 worldwide citation)

Systems and methods are provided for facilitating effective self-management of medication treatment by patients. A Smart Tray monitors and reports to third parties a patient's compliance with various medication treatment regimens. Medication containers are provided with electromagnetic tags tha ...


4
Burton H Sage, Robert I Connelly: Low-profile automatic injection device with self-emptying reservoir. Becton Dickinson and Company, Donna R Fugit Ph D, September 28, 1999: US05957895 (251 worldwide citation)

A device for delivering a liquid theraputic preparation into the body of a patient by injection into or through the skin of the patient comprises a low-profile housing having a bottom surface adapted to be brought into contact with the skin of the patient. A reservoir is disposed within the housing ...


5
Paul Yarin, Richard Fletcher, Joseph DiPisa, Glenn Philander Vonk: Systems and methods for monitoring patient compliance with medication regimens. Becton Dickinson and Company, Donna R Fugit, April 30, 2002: US06380858 (207 worldwide citation)

Systems and methods are provided for facilitating effective self-management of medication treatment by patients. A Smart Tray monitors and reports to third parties a patient's compliance with various medication treatment regimens. Medication containers are provided with electromagnetic tags tha ...


6
George T Walker, James G Nadeau, Michael C Little: Simultaneous amplification of multiple targets. Becton Dickinson and Company, Donna R Fugit, June 6, 1995: US05422252 (132 worldwide citation)

Methods for multiplex amplification of target nucleic acid sequences using a single pair of primers. Defined sequences are appended to the ends of multiple target sequences as part of the amplification reaction so that no steps in addition to amplification are required. The target sequences with the ...


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Burton H Sage, Robert I Connelly: Low-profile automatic injection device with self-emptying reservoir. Becton Dickinson and Company, Donna R Fugit, June 13, 2000: US06074369 (131 worldwide citation)

A device for delivering a liquid therapeutic preparation into the body of a patient by injection into or through the skin of the patient comprises a low-profile housing having a bottom surface adapted to be brought into contact with the skin of the patient. A reservoir is disposed within the housing ...


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Melinda S Fraiser, Catherine A Spargo, George Terrance Walker, Mark Van Cleve, David James Wright, Michael C Little: Strand displacement amplification using thermophilic enzymes. Becton Dickinson and Company, Donna R Fugit, July 15, 1997: US05648211 (126 worldwide citation)

Strand Displacement Amplification methods (thermophilic SDA) which can be performed over a broad temperature range (37.degree. C. to 70.degree. C.). The preferred temperature range for thermophilic SDA is 50.degree. C. to 70.degree. C. It has been found that certain thermophilic restriction endonucl ...


9
James G Nadeau, J Bruce Pitner, C Preston Linn, James L Schram: Detection of nucleic acids by fluorescence quenching. Becton Dickinson and Company, Donna R Fugit Ph D, July 27, 1999: US05928869 (112 worldwide citation)

A detector oligonucleotide having a sequence which forms an intramolecularly base-paired secondary structure is described for use in detecting nucleic acid target sequences and target sequence amplification. The detector oligonucleotide is further modified by linkage to two dyes which form a donor/a ...


10
Melinda S Fraiser, Catherine A Spargo, George Terrance Walker, Mark Van Cleve, David James Wright, Michael C Little: Strand displacement amplification using thermophilic enzymes. Becton Dickinson and Company, Donna R Fugit, April 28, 1998: US05744311 (112 worldwide citation)

Strand Displacement Amplification methods (thermophilic SDA) which can be performed over a broad temperature range (37.degree. C. to 70.degree. C.). The preferred temperature range for thermophilic SDA is 50.degree. C. to 70.degree. C. It has been found that certain thermophilic restriction endonucl ...