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Alfonso Gañan Cálvo: Device and method for creating spherical particles of uniform size. Universidad de Sevilla, Karl Bozicevic, Dianna L DeVore, Bozicevic Field & Francis, March 6, 2001: US06197835 (73 worldwide citation)

Spherical particles having a size on the order of 0.1 to 100 microns in size are created by systems and devices of several types. The device includes a source of a stream of gas which is forced through a liquid held under pressure in a pressure chamber with an exit opening therein. The stream of gas ...


2
Alfonso Gañán Calvo: Enhanced food products. Universidad de Sevilla, Karl Bozicevic, Dianna L DeVore, Bozicevic Field & Francis, June 19, 2001: US06248378 (72 worldwide citation)

The invention is directed to production of particles for introduction into food using a stable microjet and a monodisperse aerosol formed when the microjet dissociates. A variety of devices and methods are disclosed which allow for the formation of a stream of a first fluid (e.g. a liquid) character ...


3
Alfonso Gañan Càlvo: Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber. Universidad de Sevilla, Karl Bozicevic, Dianna L DeVore, Bozicevic Field & Francis, March 6, 2001: US06196525 (59 worldwide citation)

The present invention provides aeration methods using spherical gas bubbles having a size on the order of 0.1 to 100 microns in size. A device of the invention for producing a monodispersion of bubbles includes a source of a stream of gas which is forced through a liquid held under pressure in a pre ...


4
Roderic M K Dale, Steven L Gatton, Amy Arrow: Pulmonary delivery of protonated/acidified nucleic acids. Oligos Etc, Dianna L DeVore, Bozicevic Field & Francis, April 3, 2001: US06211162 (32 worldwide citation)

The present invention provides a method of treating bacterial respiratory infections by pulmonary administration of protonated/acidified nucleic acids. These modified nucleic acids are effective as bactericidal and/or bacteriostatic agents without regard to the class of bacteria, so are especially u ...


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Roderic M K Dale, Amy Arrow, Steven L Gatton, Terry Thompson: Protonated/acidified nucleic acids and methods of use. Oligos Etc, Dianna L DeVore, Bozicevic Field & Francis, April 3, 2001: US06211349 (23 worldwide citation)

The novel discovery that protonated nucleic acids inhibit bacterial growth is reported and methods for the preparation and therapeutic use of nuclease resistant and acid resistant protonated/acidified nucleic acids for administration to animals including man, to treat or prevent a bacterial infectio ...


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Jeffrey J Seilhammer, Glenn Nedwin, Tim Bringman, Pierre Olivier Couraud: Method of causing selective immunosuppression using HL-60-related lectins. Incyte Pharmaceuticals, Dianna L DeVore, Bozicevic Field & Francis, June 12, 2001: US06245334 (16 worldwide citation)

Pharmaceutical compositions useful in the treatment of autoimmune conditions include as an active ingredient a soluble lectin having a molecular weight of about 14 kilodaltons or a fragment thereof. The lectin or fragment binds &bgr;-galactoside-containing moieties independent of the presence or abs ...


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Stanley B Prusiner, Surachai Supattapone, Michael Scott: Clearance and inhibition of conformationally altered proteins. The Regents of the University of California, Dianna L DeVore, Bozicevic Field and Francis, April 10, 2001: US06214366 (7 worldwide citation)

The present invention provides a method of arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing insoluble protein deposit burden by the administration of branched polycationic compounds and pharmaceutical compositions containing ...


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Karl Guegler, Ruoying Tan, Michael J Rose: Methods and compositions for producing full length cDNA libraries. Incyte Pharmaceuticals, Bret E Field, Dianna L DeVore, Bozicevic Field & Francis, December 4, 2001: US06326175 (3 worldwide citation)

Methods and compositions are provided for producing full-length cDNA libraries. In the subject methods, full length first strand cDNAs are isolated using a fusion protein of an eIF-4E domain and an eIF-4G domain separated by a flexible linker. Also provided is the novel fusion protein employed in th ...