1
Benjamin Oshlack, Mark Chasin: Orally administrable opioid formulations having extended duration of effect. Purdue Pharma, Davidson Davidson and Kappel, October 19, 1999: US05968551 (282 worldwide citation)

Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains a plurality of substrates includin ...


2
Robert Chapman, Lonn S Rider, Qi Hong, Donald Kyle, Robert Kupper: Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone. Euro Celtique, Davidson Davidson and Kappel, October 31, 2006: US07129248 (64 worldwide citation)

In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.


3
Paul D Goldenheim, Richard S Sackler, Thinnayam N Krishnamurthy, Andrew Darke, Benjamin Oshlaci: Controlled/modified release oral methylphenidate formulations. Euro Celtique, Davidson Davidson and Kappel, August 1, 2006: US07083808 (29 worldwide citation)

The invention is directed to oral modified/controlled release methylphenidate formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak concentration is lower than that provided by the reference standard for immediate release methylphenidate ...


4
Benjamin Oshlack, Mark Chasin, Frank Pedi Jr: Controlled release formulations coated with aqueous dispersions of acrylic polymers. Purdue Pharma, Davidson Davidson and Kappel, July 4, 2006: US07070806 (26 worldwide citation)

A stable solid controlled release formulation having a coating derived from an aqueous dispersion of a hydrophobic acrylic polymer includes a substrate including an active agent selected from the group consisting of a systemically active therapeutic agent, a locally active therapeutic agent, a disin ...


5
Ron Linneweil: Closure for containers and reclosable containers including the same. Davidson Davidson and Kappel, January 24, 2006: US06988828 (18 worldwide citation)

The present invention relates to an air-tight closure for enhancing accessibility to contents of a container when the container is opened and for preventing exposure of the container contents to ambient air when the container is closed. The invention further relates to re-closable containers includi ...


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Benjamin Oshlack, Frank Pedi Jr: Powder-layered oral dosage forms. Purdue Pharma, Davidson Davidson and Kappel, June 13, 2006: US07060293 (12 worldwide citation)

An oral dosage form of morphine is formulated by powder-layering an homogeneous mixture of morphine sulfate and hydrous lactose impalpable onto inert beads to obtain a multiparticulate product. A plurality of the powder-layered beads may be administered either in immediate release form or in an exte ...


8
S George Kottayil, Jeffrey H Ping: Intravenous administration of tramadol. REVOGENEX IRELAND, Davidson Davidson and Kappel, February 7, 2017: US09561195 (3 worldwide citation)

A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously over a prolonged time period is disclosed. In certain embodiments, the dose is intravenously administered in a time period from about 10 minut ...


9
Franklin Jiri Call, Mark Robbeson: Steel stud anchor. Franklin Hall, Mark Robbeson, Davidson Davidson and Kappel, March 14, 2017: US09593705 (1 worldwide citation)

A metal anchoring fastener fastens millwork onto walls constructed with wall cladding fastened to steel studs. The load typical of a loaded cabinet is borne by the steel stud anchors owing to the mate between the profile of the steel stud anchor and the layers of millwork and wall cladding and steel ...


10
Lino Tavares, Ihor Shevchuk, Mark Alfonso, Geraldine Marcenyac, Kirti Valia: Felodipine transdermal device and methods. Euro Celtique, Davidson Davidson and Kappel, March 28, 2006: US07018649 (1 worldwide citation)

A method of effectively treating hypertension in humans is achieved by administering felodipine via a transdermal formulation. Preferably, the transdermal formulation is applied to the skin of the patient and maintained in contact with the skin for at least about 24 hours days, and preferably for ab ...