1
David S Bradin: Biodiesel fuel. BRI, David Bradin, November 26, 1996: US05578090 (115 worldwide citation)

A fuel additive composition including fatty acid alkyl esters and glyceryl ethers, and an alternative fuel composition that includes the fuel additive composition. Also provided is a method for preparing the fuel additive composition and the alternative fuel composition. In one embodiment, the fuel ...


2
John D Baldeschwieler: Liposomal targeting of ischemic tissue. NeXstar Pharmaceuticals, Adam Cochran, David Bradin, January 14, 1997: US05593688 (28 worldwide citation)

Liposomes of a size of less than 200 nanometers target ischemic myocardial tissue and preferentially deliver active agents to infarcted areas.


3
Ketan Desai: Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis. Voltarra Pharmaceuticals, Hultquist PLLC, David Bradin, October 14, 2014: US08859530 (14 worldwide citation)

A combination therapy for treating osteoarthritis is disclosed. The combination therapy includes the co-administration of a steroid and Zoledronic Acid. The coadministration of a steroid decreases the production of cytokines, and, therefore, decreases the pro-inflammatory effects of Zoledronic Acid. ...


4
Jong Hyun Cho, Steven J Coats, Raymond F Schinazi, Hongwang Zhang, Longhu Zhou: Purine nucleoside monophosphate prodrugs for treatment of cancer and viral infections. RFS Pharma, Emory University, Hultquist PLLC, David Bradin, December 17, 2013: US08609627 (12 worldwide citation)

The present invention is directed to compounds, compositions and methods for treating or preventing cancer and viral infections, in particular, HIV, HCV, Norovirus, Saporovirus, HSV-1, HSV-2, Dengue virus, Yellow fever, and HBV in human patients or other animal hosts. The compounds are certain 6-sub ...


5
Sandrine Bourgeois, Elias Fattal, Antoine Andremont, Patrick Couvreur: Galenic pectinate formulation for colon-targeted delivery of antibiotic-inactivating enzymes and method of use thereof. Da Volterra, David Bradin, Intellectual Property Technology Law, February 3, 2009: US07485294 (4 worldwide citation)

Forms of colonic delivery suited to be used orally and designed for colonic delivery of active ingredients selected from the group comprising enzymes capable of inactivating macrolide antibiotics and related compounds, enzymes capable of inactivating quinolones, and β-lactamases.


6
Raymond F Schinazi, Richard Anthony Whitaker, Tamara Rosario McBrayer, Steven J Coats: infections, including Norovirus infections, Nucleoside derivatives for treatment of. Hultquist PLLC, David Bradin, April 9, 2013: US08415321 (2 worldwide citation)

A method and composition for treating a host infected with a Caliciviridae virus, such as a Norovirus, comprising administering an effective treatment amount of a described modified nucleoside or a pharmaceutically acceptable salt thereof, is provided.


7
Christopher K Whitmarsh: Biphasic nanoporous vitreous carbon material and method of making the same. Carbon Ceramics Company, David Bradin, Steven J Hultquist, Intellectual Property Technology Law, January 4, 2011: US07862897 (1 worldwide citation)

A biphasic nanoporous vitreous carbon material with a cementitious morphology characterized by presence of non-round porosity, having superior hardness and tribological properties, as useful for high wear-force applications. The biphasic nanoporous vitreous carbon material is produced by firing, und ...


8
Helene Huguet, Antoine Andremont, Nicolas Tsapis, Elias Fattal: Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules. David Bradin, Hultquist IP, November 1, 2011: US08048413 (1 worldwide citation)

Compositions which deliver adsorbents, alone or in combination with active drug “degrading molecules,” in a site-specific manner to the intestine, and which eliminate or at least lower the concentration of residual unwanted material within the intestine, are disclosed. Methods of treatment using the ...


9
Antoine Andremont, Helene Huguet: Colonic delivery of metallo-dependent enzymes. DA Volterra, Assistance Publique Hopitaux de Paris, Universite Paris Diderot Paris 7, Hultquist PLLC, David Bradin, September 25, 2012: US08273376 (1 worldwide citation)

Drug delivery systems for reducing the quantity of residual antibiotics reaching the colon following oral or parenteral antibiotic therapy, and for delivering metallo-dependent enzymes, and methods of use thereof, are disclosed. The drug delivery systems include pectin beads that encapsulate the act ...


10
Thomas E Johnson, Billy T Fowler: Methods, compositions, and apparatuses for forming macrocyclic compounds. Intellectual Property Technology Law, Steven J Hultquist, David Bradin, May 4, 2010: US07709632 (1 worldwide citation)

This invention relates to methods, compositions, and apparatuses for producing macrocyclic compounds. First, one or more reactants are provided in a reaction medium, which are capable of forming the macrocyclic compound through a desired reaction pathway that includes at least cyclization, and which ...



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