1
David Sherrer
Dan A Steinberg, David W Sherrer: Optical waveguide switch having stepped waveguide holding member. Shipley Company L L C, Dann Dorfman Herrell and Skillman P C, October 14, 2003: US06633691

A first waveguide holding member has a principal surface which confronts the principal surface of a second waveguide holding member. Each principal surface has a stepped configuration defined by an upper surface region, a lower surface region and a transverse region which separates the upper and low ...


2
Louis C Argenta, Michael J Morykwas: Wound treatment employing reduced pressure. Wake Forest University, Dann Dorfman Herrell and Skillman P C, June 10, 1997: US05636643 (682 worldwide citation)

A method of treating tissue damage comprises applying a negative pressure to a wound sufficient in time and magnitude to promote tissue migration and thus facilitate closure of the wound. The method is applicable to wounds, burns, infected wounds, and live tissue attachments. A wound treatment appar ...


3
Louis C Argenta, Michael J Morykwas: Method of treating tissue damage and apparatus for same. Wake Forest University, Dann Dorfman Herrell and Skillman, July 8, 1997: US05645081 (658 worldwide citation)

The invention disclosed is a method of treating tissue damage comprising applying a negative pressure to a wound sufficient in time and magnitude to promote tissue migration and thus facilitate closure of the wound. The method is applicable to wounds, burns, infected wounds, and live tissue attachme ...


4
Michael P Whitman: Electromechanical driver device for use with anastomosing, stapling, and resecting instruments. Power Medical Interventions, Dann Dorfman Herrell and Skillman P C, September 3, 2002: US06443973 (649 worldwide citation)

An electromechanical driver for use in gastrointestinal tract surgery, including a flexible sheath and a handle, is provided. Also dislosed are a series of surgical attachments which may be utilized in conjunction with the electromechanical driver. The handle of the driver includes at least one moto ...


5
Peter Wilding, Larry J Kricka, Jay N Zemel: Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems. Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, June 10, 1997: US05637469 (565 worldwide citation)

Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow system that includes a sample flow channel extending from the inlet port. The mesoscale flow system furthe ...


6
Peter Wilding, Larry J Kricka: Mesoscale polynucleotide amplification device and method. Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, March 12, 1996: US05498392 (545 worldwide citation)

Disclosed are devices for amplifying a preselected polynucleotide in a sample by conducting a polynucleotide polymerization reaction. The devices comprise a substrate microfabricated to define a sample inlet port and a mesoscale flow system, which extends from the inlet port. The mesoscale flow syst ...


7
Peter Wilding, Larry J Kricka: Mesoscale polynucleotide amplification devices. The Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, December 24, 1996: US05587128 (524 worldwide citation)

Disclosed are devices for amplifying a preselected polynucleotide in a sample by conducting a polynucleotide amplification reaction. The devices are provided with a substrate microfabricated to include a polynucleotide amplification reaction chamber, having at least one cross-sectional dimension of ...


8
Peter Wilding, Larry J Kricka: Analysis based on flow restriction. Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, January 23, 1996: US05486335 (342 worldwide citation)

Disclosed are devices and methods for detecting the presence of a preselected analyte in a fluid sample. The invention provides a device comprising a solid substrate, typically on the order of a few millimeters thick and approximately a 0.2 to 2.0 centimeters square, microfabricated to define a samp ...


9
Peter Wilding, Larry J Kricka, Jay N Zemel: Fluid handling methods for use in mesoscale analytical devices. Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, June 3, 1997: US05635358 (335 worldwide citation)

Disclosed are devices and methods for analyzing a fluid cell containing sample. The devices are composed of a solid substrate, microfabricated to define at least one sample inlet port and a mesoscale flow system. The mesoscale flow system includes a sample flow channel, extending from the inlet port ...


10
Peter Wilding, Larry J Kricka: Mesoscale sample preparation device and systems for determination and processing of analytes. Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, March 10, 1998: US05726026 (326 worldwide citation)

A mesoscale sample preparation device capable of providing microvolume test samples, separated into a cell-enriched fraction and a fraction of reduced cell content, for performing various analyses, such as binding assays, determinations involving polynucleotide amplification and the like. Analytical ...



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