1
Richard M Formato, Robert F Kovar, Paul Osenar, Nelson Landrau, Leslie S Rubin: Composite solid polymer electrolyte membranes. Foster Miller, Linda M Buckley, Christine C O&apos Day, Edwards & Angell, June 19, 2001: US06248469 (136 worldwide citation)

The present invention relates to composite solid polymer electrolyte membranes (SPEMs) which include a porous polymer substrate interpenetrated with an ion-conducting material. SPEMs of the present invention are useful in electrochemical applications, including fuel cells and electrodialysis.


2
Alexei Kochkine, Jef Fensholdt, Henrik M Pfundheller: Synthesis of [2.2.1]bicyclo nucleosides. Exiqon, Peter F Corles, Christine C O&apos Day, Edwards & Angell, October 28, 2003: US06639059 (88 worldwide citation)

A synthesis of [2.2.1]bicyclo nucleosides which is shorter and provides higher overall yields proceeds via the key intermediate of the general formula III, wherein R


3
Alexei Kochkine, Jef Fensholdt, Henrik M Pfundheller: Synthesis of [2.2.1]bicyclo nucleosides. Exiqon, Peter F Corless, Christine C O&apos Day, Edwards & Angell, May 11, 2004: US06734291 (87 worldwide citation)

A synthesis of [2.2.1]bicyclo nucleosides which is shorter and provides higher overall yields proceeds via the key intermediate of the general formula III, wherein R


4
Annette Skinhøj, Poul Bertelsen: Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs). Nycomed Danmark, Peter F Corless, Christine C O&apos Day, Edwards & Angell, July 29, 2003: US06599529 (83 worldwide citation)

An oral pharmaceutical modified release multiple-units composition for the administration of a therapeutically and/or prophylactically effective amount of a non-steroid anti-inflammatory drug substance to obtain both a relatively fast onset of the therapeutic effect and the maintenance of a therapeu ...


5
Peter Dwight Spohn, Dean David Dinsmore: Peelable PTFE sheaths and methods for manufacture of same. TFX Medical, Peter F Corless, Christine C O&apos Day, Edwards & Angell, September 24, 2002: US06454744 (53 worldwide citation)

The present invention provides improved medical introducer devices which incorporate a single or multi-layer PTFE peelable sheath. Devices of the present invention are suitable for use in inserting an ancilliary medical device, e.g., a catheter, guide wire and the like, into a patient. Methods of th ...


6
Eduardo Marban: Methods for treatment of disorders of cardiac contractility. Johns Hopkins University, Peter F Corless, Christine C O&apos Day, Edwards & Angell, May 27, 2003: US06569862 (50 worldwide citation)

The present invention relates to methods for modulating calcium sensitivity of cardiac muscle. In preferred aspects, the invention provides methods for enhancing myocardial contractility and cardiac performance, and methods for treatment of heart failure and other disorders associated with cardiac c ...


7
Poul Bertelsen, Niels Gjørløv Hansen, Hermann Ruckendorfer, Shigeru Itai: Quick release pharmaceutical compositions of drug substances. Nycomed Danmark, Peter F Corless, Christine C O&apos Day, Edwards & Angell, March 30, 2004: US06713089 (42 worldwide citation)

The present invention relates to an oral modified release pharmaceutical composition for the administration of a therapeutically and/or prophylactically effective amount of an active substance (a drug substance), to obtain a relatively fast or quick onset of the therapeutic and/or prophylactic effec ...


8
Peter Dwight Spohn, Dean David Dinsmore: Peelable PTFE sheaths and methods for manufacture of same. TFX Medical, Peter F Coreless, Christine C O&apos Day, Edwards & Angell, December 16, 2003: US06663595 (40 worldwide citation)

The present invention provides improved medical introducer devices which incorporate a single or multi-layer PTFE peelable sheath. Devices of the present invention are suitable for use in inserting an ancilliary medical device, e.g., a catheter, guide wire and the like, into a patient. Methods of th ...


9
Jorgen Hyldgaard, Jimmi Larsen, Anette Severin Jensen: Oil-in-water emulsion containing C10-C24 fatty acid derivatives for treating skin of mammals. Plum Kerni Produktion, Peter F Corless, Christine C O&apos Day, Edwards & Angell, January 29, 2002: US06342208 (33 worldwide citation)

An oil-in-water emulsion for application on a skin surface is disclosed. The emulsion comprises an oily phase and an aqueous phase. The oily phase comprises a first lipid of vegetable or animal origin. The emulsion is stabilized by containing at least one surfactant/emulsifier. The surfactant/emulsi ...


10
Christoph Arth, Claus Meese, Dietrich Wilhelm Schacht, Hans Michael Wolff: Transdermal therapeutic system TTS containing tolterodine. Schwarz Pharma, Peter F Corless, Christine C O&apos Day, Edwards & Angell, August 31, 2004: US06783769 (31 worldwide citation)

The invention relates to a transdermal therapeutic system (TTS) for transcutaneously administering tolterodine over a period of several days and to a method for producing the same. The TTS contains a self-adhesive layer-shaped matrix composition which contains a (meth)acrylate copolymer comprising a ...