1
Wei Dong Tian, Pierre Trepagnier: Generation of spatially-averaged excitation-emission map in heterogeneous tissue. Argose, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, July 22, 2003: US06597932 (290 worldwide citation)

An instrument for evaluating fluorescence of a heterogeneous tissue includes means for exciting a two-dimensional portion of the tissue surface with excitation radiation at a plurality of excitation wavelengths, means for collecting emission radiation from the two-dimensional portion of the tissue s ...


2
Pierre Trepagnier: Asynchronous fluorescence scan. Argose, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, October 28, 2003: US06639668 (275 worldwide citation)

The present invention is directed to asynchronous scanning devices and methods of using asynchronous scanning to acquire fluorescence data from a sample, such as biological tissue, to facilitate diagnosis of the presence or absence of disease or other abnormality in the sample. The present invention ...


3
Edith Mathiowitz, Yong Shik Jong, Kim Boekelheide: Polymeric gene delivery system. Brown University Research Foundation, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, September 16, 2003: US06620617 (85 worldwide citation)

A means for obtaining efficient introduction of exogenous genes into a patient, with long term expression of the gene, is disclosed. The gene, under control of an appropriate promoter for expression in a particular cell type, is encapsulated or dispersed with a biocompatible, preferably biodegradabl ...


4
Joseph P Hammang, E Edward Baetge, William G Tsiarias, Peter D Spear: Device and method for treating ophthalmic diseases. Neurotech, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, August 20, 2002: US06436427 (48 worldwide citation)

The invention provides a method for delivering biologically active molecules to the eye by implanting biocompatible capsules containing a cellular source of the biologically active molecule. Also provided is a method of treating ophthalmic diseases using biocompatible capsules.


5
Weng Tao, David H Rein, Brenda J Dean, Paul F Stabila, Moses B I Goddard: ARPE-19 as a platform cell line for encapsulated cell-based delivery. Neurotech, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo PC, March 26, 2002: US06361771 (31 worldwide citation)

ARPE-19 cells were evaluated as a platform cell line for encapsulated and un-encapsulated cell-based delivery technology. ARPE-19 cells were found to be hardy (the cell line is viable under stringent conditions, such as in central nervous system or intra-ocular environment); can be genetically modif ...


6
Rebecca Li, David Rhein: Device containing cell-supporting yarn matrix encapsulated in a semi-permeable membrane. Neurotech, Christina V Karnakis Esq, Ivor R Elrifi Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, September 30, 2003: US06627422 (27 worldwide citation)

A device is provided containing cells or tissue distributed on a filamentous cell-supporting matrix which is encapsulated by a semi-permeable membrane which can be immunoisolatory. The matrix may be formed of a plurality of monofilaments twisted into yarn that is in non-woven strands, or of the mono ...


7
E Edward Baetge, Thomas Hunziker, Alain Limat, Vincent Ronfard: Cell paste comprising keratinocytes and fibroblasts. Modex Therapeutiques, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, January 6, 2004: US06673603 (22 worldwide citation)

The present invention provides the use and composition of matter of angiogenic or other growth factors expressed by combining various types and stages of differentiation of allogeneic human cell strains or lines in unencapsulated pastes (mixed with or applied to extracellular matrix material or synt ...


8
Cynthia Green, Victor Kotelianski, Antonin de Fougerolles, John Carulli, Catherine Hession: Nucleic acids encoding members of the human B lymphocyte activation antigen B7 family and methods of using the same. CuraGen Corporation, Biogen, Ivor R Elrifi Esq, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo P C, August 6, 2002: US06429303 (18 worldwide citation)

An isolated BLAA polynucleotide and the membrane-associated or secreted polypeptide encoded by the BLAA polynucleotide are disclosed. Also disclosed are the antibodies that immunospecifically bind to a BLAA polypeptide or any derivative, variant, mutant or fragment of the BLAA polypeptide, polynucle ...


9

10
Samuel Weiss, Brent Reynolds: Multipotent neural stem cell cDNA libraries. Neurospheres Holdings, Ivor R Elrifi Esquire, Christina V Karnakis Esq, Mintz Levin Cohn Ferris Glovsky and Popeo PC, June 4, 2002: US06399369 (15 worldwide citation)

cDNA libraries may be obtained from neural cell cultures produced by using growth factors to induce the proliferation of multipotent neural stem cells. The libraries may be obtained from both cultured normal and dysfunctional neural cells and from neural cell cultures at various stages of developmen ...



Click the thumbnails below to visualize the patent trend.