1
Matthew J Schurman, Walter J Shakespeare: Method and apparatus for monitoring glucose levels in a biological tissue. GlucoLight Corporation, Thomas J Engellenner, Charlton Shen, Nutter McClennen & Fish, August 7, 2007: US07254429 (365 worldwide citation)

In accordance with the invention, a low coherence interferometer is used to non-invasively monitor the concentration of glucose in blood by shining a light over a surface area of human or animal tissue, continuously scanning the light over a two dimensional area of the surface, collecting the reflec ...


2
Matthew J Schurman: Method and apparatus for tissue oximetry. GlucoLight Corporation, Thomas J Engellenner, Charlton Shen, Nutter McClennen & Fish, April 8, 2008: US07356365 (260 worldwide citation)

In accordance with the invention, the oxygenation of blood-profused tissue is measured by shining light into the profused tissue and analyzing the light reflected within the tissue. The light is reflected by cell walls in the tissue and is partially absorbed by hemoglobin in the blood. Since the ext ...


3
Matthew J Schurman, Walter Jeffrey Shakespeare: OCT based method for diagnosis and therapy. GlucoLight Corporation, Thomas J Engellenner, Charlton Shen, Nutter McClennen & Fish, March 31, 2009: US07510849 (252 worldwide citation)

This invention relates to a method of diagnosing or treating a biological subject, such as a person or animal, comprising the steps of subjecting at least a microsample of the subject's tissue to a physiological perturbation and measuring the response of the microsample to the perturbation using opt ...


4
Keith Eldridge, Paul Meskonis, Robert Hall, Kenneth A Burke, Scott Volk, Mark Johnson, Brian Mackay, Steven Dardinski: Methods and apparatus for control configuration with versioning, security, composite blocks, edit selection, object swapping, formulaic values and other aspects. Invensys Systems, Nutter McClennen & Fish, David J Powsner, Charlton Shen, September 18, 2007: US07272815 (234 worldwide citation)

Methods and apparatus for configuring process, environmental, industrial and other control systems generate and/or utilize models representing configurations of control systems and/or the systems controlled by them. Records of changes to the models or the configurations represented by them are maint ...


5
Charles D Lennox, Steven M Johnson, Susan Beinor, Maria Benson, Don Paul Nogueira, John W Carroll, Helen Maslocka: Method and device for rapidly inducing and then maintaining hypothermia. MedCool, Thomas J Engellenner, Charlton Shen, Nutter McClennen & Fish, May 30, 2006: US07052509 (29 worldwide citation)

A cooling system includes a console and a tissue cooling device such as a head-cooling device. An operator applies the head-cooling device to the head of a patient at risk for ischemic injury. The console provides a cooling fluid to a fluid circulation space located between the cooling device and th ...


6
Charles D Lennox, Steven M Johnson, Susan Beinor, Maria Benson, Don Paul Nogueira, John W Carroll, Helen Maslocka: Method and apparatus for reducing body temperature of a subject. MedCool, Thomas J Engellenner, Charlton Shen, Nutter McClennen & Fish, November 24, 2009: US07621945 (26 worldwide citation)

A cooling system includes a console and a tissue cooling device such as a head-cooling device. An operator applies the head-cooling device to the head of a patient at risk for ischemic injury. The console provides a cooling fluid to a fluid circulation space located between the cooling device and th ...


7
Charles D Lennox: Methods and apparatus for thermally activating a console of a thermal delivery system. MedCool, Thomas J Engellenner, Charlton Shen, Nutter McClennen & Fish, June 6, 2006: US07056334 (17 worldwide citation)

A thermal delivery system includes a base unit having a thermal regulation source and a console configured to deliver cooling fluid to a body-cooling device to induce hypothermia and aid in resuscitation of a patient. When a user docks the console with the base station, the console thermally contact ...


8
James G Calvin: Control system methods and apparatus for inductive communication across an isolation barrier. Invensys Systems, Nutter McClennen & Fish, David J Powsner, Charlton Shen, May 13, 2008: US07372914 (16 worldwide citation)

Improved control apparatus and methods transfer information between devices, such as controllers and field devices, utilizing a modulator that generates a pulse width modulated (PWM) signal containing information to be transferred by a first of the devices, e.g., the controller, to the second device ...


9
Charles D Lennox: Interstitial brain cooling probe and sheath apparatus. MedCool, Thomas J Engellenner, Charlton Shen Nutter McClennen & Fish, August 22, 2006: US07094234 (11 worldwide citation)

Disclosed is an apparatus and method for preventing secondary ischemic injury in the brain. The apparatus includes an interstitial brain probe and an introducer sheath, which are placed into an ischemic region of the brain by stereotaxic surgical technique. The interstitial brain probe and introduce ...


10
Charles D Lennox: Method and device for rapidly inducing hypothermia. MedCool, Thomas J Engellenner, Charlton Shen, Nutter McClennen & Fish, March 24, 2009: US07507250 (10 worldwide citation)

Disclosed is a system and method for inducing therapeutic levels of hypothermia in a patient in the emergent care setting. The system consists of a small battery operated console and one or more garments. The garments are connected to the console by one or more umbilicals. The console provides cold ...