1
Charles Rice, Timothy Tellinghuisen, Joseph Marcotrigiano: Structure of the hepatitis C NS5A protein. The Rockefeller University, Thompson Coburn, Charles P Romano, February 22, 2011: US07894996 (16 worldwide citation)

The present invention provides a crystallized N-terminal domain of an NS5A protein of hepatitis C virus, methods of producing the same and methods of use thereof. The present invention also relates to structural elements of the N-terminal domain of hepatitis C virus NS5A protein, and methods of inhi ...


2
Joanne J Fillatti, Greg E Keithly, Toni Voelker, Tim Ulmasov: Soybean seed and oil compositions and methods of making same. Monsanto Technology, Thompson Coburn, Charles P Romano, September 7, 2010: US07790953 (11 worldwide citation)

Methods for obtaining soybean plants that produce seed with low linolenic acid levels and moderately increased oleic levels are disclosed. Also disclosed are methods for producing seed with low linolenic acid levels, moderately increased oleic levels and low saturated fatty acid levels. These method ...


3
Charles Rice, Brett D Lindenbach, Matthew J Evans, Christopher Jones: Infectious, chimeric hepatitis C virus, methods of producing the same and methods of use thereof. The Rockefeller University, Thompson Coburn, Charles P Romano, March 9, 2010: US07674612 (7 worldwide citation)

The present invention provides infectious recombinant Hepatitis C Viruses (HCV), and vectors, cells and animals comprising the same. The present invention provides methods of producing infectious recombinant HCV, and their use in identifying anti-HCV therapeutic agents, as well as sequences of HCV a ...


4
Mary Fernandes: Methods for enhancing drought tolerance in plants and compositions thereof. Monsanto Technology, Thompson Coburn, Charles P Romano, August 31, 2010: US07786353 (7 worldwide citation)

Increased tolerance to drought in a plant is provided by introducing DNA expressing a bacterial cold shock protein.


5
Toni M Kutchan, Meinhart H Zenk, Torsten Grothe: Salutaridinol 7-O-acetyltransferase and derivatives thereof. Donald Danforth Plant Science Center, Thompson Coburn, Charles P Romano Senior Patent Agent, June 24, 2008: US07390642 (6 worldwide citation)

This invention provides: (A) a protein the sequence of which is in FIG. 8 (SEQ. ID n° 14), or a fragment thereof having at least 15 amino acids, or a variant thereof, having at least 70% identity with FIG. 8 (SEQ. ID n° 14) over a length of at least 400 amino acids; (B) a peptide comprising a fragme ...


6
Joanne J Fillatti, Greg E Keithly, Toni Voelker, Tim Ulmasov: Soybean seed and oil compositions and methods of making same. Monsanto Technology, Thompson Coburn, Charles P Romano, Chunping Li, December 17, 2013: US08609953 (3 worldwide citation)

Methods for obtaining soybean plants that produce seed with low linolenic acid levels and moderately increased oleic levels are disclosed. Also disclosed are methods for producing seed with low linolenic acid levels, moderately increased oleic levels and low saturated fatty acid levels. These method ...


7
Kim A Beazley, Paolo Castiglioni, Mark A Dizigan, Rebecca A Kelly, John Alan Korte, Amanda Rock, Christine Voyles: Corn plant event MON87460 and compositions and methods for detection thereof. Monsanto Technology, Thompson Coburn, Charles P Romano, May 28, 2013: US08450561 (3 worldwide citation)

The present invention provides a transgenic corn even MON87460, and cells, seeds, and plants comprising DNA diagnostic for the corn event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for MON87460 in a sample, methods for detecting the presence of MON8 ...


8
Li Qun Gu, Yong Wang, Kai Tian: Nanopore-facilitated single molecule detection of nucleic acid. The Curators of the University of Missouri, Thompson Coburn, Charles P Romano, July 19, 2016: US09395353 (2 worldwide citation)

The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini. The improved nanopore ...


9
Toni Armstrong, Kenneth Barton, Laura J Crow, Larry A Gilbertson, Shihshieh Huang, Yong Huang, Brian J Martinell, Michael W Petersen, Kenneth J Piller, Qi Wang, Xudong Ye: Methods for enhancing segregation of transgenes in plants. Monsanto Technology, Thomapson Coburn, Charles P Romano, June 14, 2011: US07960610 (2 worldwide citation)

The compositions and methods are provided that enhance the selection of transgenic plants having two T-DNA molecules integrated into a plant genome at different physical and genetic loci. The compositions are DNA constructs that comprise novel arrangements of T-DNA molecules containing genes of inte ...


10
Thomas Malvar, Shihshieh Huang, Alessandra Frizzi, Mike Kerns: Corn seed comprising novel opaque modifiers and related methods. Monsanto Technology, Thompson Coburn, Charles P Romano, Chunping Li, October 30, 2012: US08299335 (2 worldwide citation)

Novel corn opaque modifier loci, associated molecular markers and methods for obtaining the loci, markers, and resultant seed are provided. Vitreous seed with reduced alpha-zein storage protein content that contain the opaque modifier loci are also described. Processes for obtaining milled corn seed ...



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