1
Kelly G Ammann, Ralph E Burns, Ernest V Hansberry, Glenn A Horner, Cheryl A Jakub, John E Kling, Donald J Nieglos, Robert E Schneider, Robert J Smith: Automated process for isolating and amplifying a target nucleic acid sequence. Gen Probe Incorporated, Charles B Cappellari, Rothwell Figg Ernst & Manbeck, January 1, 2002: US06335166 (144 worldwide citation)

An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample ...


2
Kelly G Ammann, Ralph E Burns, Ernest V Hansberry, Glenn A Horner, Cheryl A Jakub, John E Kling, Donald J Nieglos, Robert E Schneider, Robert J Smith: Method and apparatus for performing a magnetic separation purification procedure on a sample solution. Gen Probe Incorporated, Charles B Cappellari Esq, Rothwell Figg Ernst & Manbeck P C, August 12, 2003: US06605213 (135 worldwide citation)

An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample ...


3
Kelly G Ammann, Ralph E Burns, Ernest V Hansberry, Glenn A Horner, Cheryl A Jakub, John E Kling, Donald J Nieglos, Robert E Schneider, Robert J Smith: Automated process for isolating and amplifying a target nucleic acid sequence. Gen Probe Incorporated, Charles B Cappellari, Richard Wydeven, May 10, 2005: US06890742 (104 worldwide citation)

An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample ...


4
Michael M Becker, Gary P Schroth: Molecular torches. Gen Probe Incorporated, Charles B Cappellari, Sheldon O Heber, March 26, 2002: US06361945 (104 worldwide citation)

The present invention features “molecular torches” and the use of molecular torches for detecting the presence of a target nucleic acid sequence. Molecular torches contain a target binding domain, a target closing domain, and a joining region. The target binding domain is biased towards the target s ...


5
Galo F Acosta, Jeffrey D Bransky, Robert Case, Gregory J Foster, Kristi K Myers, Thomas M Shimei, Andrew J Woodhead: Assay work station. Gen Probe Incorporated, Charles B Cappellari, Rothwell Figg Ernst & Manbeck P C, July 3, 2001: US06254826 (103 worldwide citation)

A work station for simultaneously performing multiple assays includes a base structure, a receptacle rack assembly received within a receptacle rack well formed in the base structure, a pipette tip rack assembly received within a pipette tip rack well formed in the base structure, a multiple conduit ...


6
Kelly G Ammann: Transport mechanism. Gen Probe Incorporated, Charles B Cappellari Esq, Rothwell Figg Ernst & Manbeck P C, July 20, 2004: US06764649 (79 worldwide citation)

An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample ...


7
David Bruce Lackey, Nanibhushan Dattagupta, Daniel Louis Kacian: Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases. Gen Probe Incorporated, Charles B Cappellari, Carlos A Fisher, April 14, 1998: US05739311 (71 worldwide citation)

The present invention relates to methods of synthesizing phosphorothioate oligonucleotides. In particular, it relates to the use of certain restriction endonucleases to cleave phosphorothioate oligonucleotides which contain restriction endonuclease recognition sequences. These restriction sequences ...


8
Michael M Becker, Gary P Schroth: Molecular torches. Gen Probe Incorporated, Charles B Cappellari, Sheldon O Heber, March 18, 2003: US06534274 (67 worldwide citation)

The present invention features “molecular torches” and the use of molecular torches for detecting the presence of a target nucleic acid sequence. Molecular torches contain a target binding domain, a target closing domain, and a joining region. The target binding domain is biased towards the target s ...


9
Nanibhushan Dattagupta, Paul Douglas Stull, Marc Spingola, Daniel Louis Kacian: Isothermal strand displacement nucleic acid amplification. Gen Probe Incorporated, Charles B Cappellari, April 10, 2001: US06214587 (66 worldwide citation)

Methods for amplifying target nucleic acid sequences using a nucleic acid polymerase lacking 5′ exonuclease activity and a set of oligonucleotide primers. Preferably, a primer array is used. The primer array contains two sets of primers. One set contains at least two complementary primers. The other ...


10
Glenn A Horner, Shirley J Johnson, Robert E Schneider, Robert J Smith, Gus Tseo: Reaction receptacle apparatus. Gen Probe Incorporated, Charles B Cappellari, Richard Wydeven, February 11, 2003: US06517782 (64 worldwide citation)

A reaction receptacle apparatus includes one or more individual receptacles for containing chemical or biological substances. The one or more receptacles are arranged to be engaged by tubular elements of a substance transfer device for transferring substances into or out of the individual receptacle ...