1
David A Edwards, Richard P Batycky, Lloyd Johnston: Highly efficient delivery of a large therapeutic mass aerosol. Alkermes, Elmore Patent Law Group P C, Carolyn S Elmore, Darlene A Vanstone, July 7, 2009: US07556798 (43 worldwide citation)

A method for delivering an agent to the pulmonary system, in a single, breath-activated step or a single breath, comprises administering from a receptacle enclosing a mass of particles, to a subject's respiratory tract, particles which have a tap density of less than 0.4 g/cm3 and deliver at least a ...


2
Raymond T Bartus, Dwaine F Emerich: Pulmonary delivery in treating disorders of the central nervous system. Advanced Inhalation Research, Elmore Craig & Vanstone P C, Carolyn S Elmore, Anne I Craig, December 27, 2005: US06979437 (39 worldwide citation)

A method for treating a disorder of the central nervous system includes administering to the respiratory tract of a patient a drug which is delivered to the pulmonary system, for instance to the alveoli or the deep lung. The drug is administered at a dose which is at least about two-fold less than t ...


3
David A Edwards, Richard P Batycky, Lloyd Johnston: High efficient delivery of a large therapeutic mass aerosol. Advanced Inhalation Research, Elmore Craig P C, Anne I Craig, Carolyn S Elmore, February 22, 2005: US06858199 (38 worldwide citation)

A method for delivering a therapeutic dose of a bioactive agent to the pulmonary system, in a single, breath-activated step, comprises administering from a receptacle enclosing a mass of particles, to a subject's respiratory tract, particles which have a tap density of less than 0.4 g/cm3 and delive ...


4
Zhenwei Miao, Ying Sun, Suanne Nakajima, Datong Tang, Frank Wu, Guoyou Xu, Yat S Or, Zhe Wang: Macrocyclic hepatitis C serine protease inhibitors. Enanta Pharmaceuticals, Carolyn S Elmore, Elmore Patent Law Group, October 13, 2009: US07601709 (35 worldwide citation)

The present invention relates to compounds of Formula I, II or Ill, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: wherein W is a substituted or unsubstituted heterocyclic ring system. The compounds inhibit serine protease activity, particularly the activity of hepatitis c virus ...


5
Yonghua Gai, Deqiang Niu, Yat Sun Or, Zhe Wang: Quinoxalinyl tripeptide hepatitis C virus inhibitors. Enanta Pharmaceuticals, Carolyn S Elmore, Edgar W Harlan, Elmore Patent Law Group P C, December 22, 2009: US07635683 (35 worldwide citation)

The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere w ...


6
David A Edwards, Richard P Batvcky, Lloyd Johnston: Highly efficient delivery of a large therapeutic mass aerosol. Advanced Inhalation Research, Elmore Craig & Vanstone P C, Anne I Craig, Carolyn S Elmore, July 26, 2005: US06921528 (34 worldwide citation)

A method for delivering a therapeutic dose of a bioactive agent to the pulmonary system, in a single, breath-activated step, comprises administering from a receptacle enclosing a mass of particles, to a subject's respiratory tract, particles which have a tap density of less than 0.4 g/cm3 and delive ...


7
Joel D Moore, Deqiang Niu, Guoyou Xu, Dong Liu, Yat Sun Or, Zhe Wang: Phosphorus-containing hepatitis C serine protease inhibitors. Enanta Pharmaceuticals, Carolyn S Elmore, Edgar W Harlan, Elmore Patent Law Group P C, September 1, 2009: US07582605 (34 worldwide citation)

The present invention relates to phosphorus-derived compounds of Formula I or Formula II, or a pharmaceutically acceptable salt, ester, or prodrug, thereof, which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of ...


8
Sujit K Basu, Jeffrey Hrkach, Michael Lipp, Katharina Elbert, David A Edwards: Particles for inhalation having sustained release properties. Advanced Inhalation Research, Elmore Patent Law Group PC, Carolyn S Elmore, May 23, 2006: US07048908 (33 worldwide citation)

The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to particles suitable for use in the method. In particular, the invention relates to a method for the pulmonary ...


9
Jeffrey S Hrkach: Low dose pharmaceutical powders for inhalations. Civitas Therapeutics, Elmore Patent Law Group P C, Carolyn S Elmore, Darlene A Vanstone, June 7, 2011: US07954491 (33 worldwide citation)

The invention relates to a method of delivering an agent to the pulmonary system of a compromised patient, in a single breath-activated step, comprising administering a particle mass comprising an agent from an inhaler containing less than 5 milligrams of the mass, wherein at least about 50% of the ...


10
Stephen E Zale, Mir Mukkaram Ali: Cancer cell targeting using nanoparticles. BIND Therapeutics, Elmore Patent Law Group P C, Edgar W Harlan, Carolyn S Elmore Esq, December 10, 2013: US08603499 (33 worldwide citation)

The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes produc ...