1
Tao Zheng: High-coverage and natural-looking cosmetic compositions and uses thereof. Avon Products, David M Joyal, Joan M McGillycuddy, Brian C Remy, November 26, 2013: US08591924 (16 worldwide citation)

Topical compositions comprising at least one matte-finished interference pigment combined with one or more microsphere(s) and elastomer(s) are provided, as well as methods for using such compositions in cosmetics and dermatological products that afford high coverage of flaws or imperfections, while ...


2
Georg Fertig, Frank Herting, Manfred Kubbies, Anja Limberg, Ulrike Reiff, Michael Weidner: N-monoacylated o-phenylenediamines. Hoffmann La Roche, George W Johnston, Patricia S Rocha Tramaloni, Brian C Remy, April 24, 2007: US07208491 (14 worldwide citation)

Mono-acylated o-phenylendiamines derivatives of formula I wherein X and R are as described herein, have been found useful for the treatment of diseases mediated by the inhibition of histone deacetylase, such as cancer.


3
Rainer Haag, Ulrike Leser Reiff, Anja Limberg, Michael Weidner, Gerd Zimmermann: N-monoacylated derivatives of o-phenylenediamines, their analogs and their use as pharmaceutical agents. Hoffman La Roche, George W Johnston, Patricia S Rocha Tramaloni, Brian C Remy, March 22, 2005: US06869953 (13 worldwide citation)

New compounds represented by the formula or pharmaceutically acceptable salts or prodrugs thereof, wherein X1 and X2 are each independently selected from a CH group or a nitrogen atom; and R is an optionally substituted five or six membered nonaromatic carbocyclic ring or a nonaromatic or aromatic h ...


4
Yvo Graus, Jacques Himber, Miranda Jansen Molenaar, Dorothee Kling, Erhard Kopetzki, Paul Parren, Frank Rebers, Beat Steiner, Anne Stern, Pamela Strein, Kay Gunnar Stubenrauch, Jan van de Winkel, Martine van Vugt: Anti-P-selectin antibodies. Hoffman La Roche, George W Johnston, Dennis P Tramaloni, Brian C Remy, July 21, 2009: US07563441 (12 worldwide citation)

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff ...


5
Qingjie Ding, Paul Gillespie, Kyungjin Kim, Warren William McComas, Agostino Perrotta: Diaminothiazoles having antiproliferative activity. Hoffmann La Roche, George W Johnston, Patricia S Rocha Tramaloni, Brian C Remy, August 22, 2006: US07094896 (7 worldwide citation)

Disclosed are novel diaminothiazoles that are selective inhibitors of Cdk4. These compounds and their pharmaceutically acceptable salts and esters are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed a ...


6
Yvo Graus, Jacques Himber, Miranda Jansen Molenaar, Dorothee Kling, Erhard Kopetzki, Paul Parren, Frank Rebers, Beat Steiner, Anne Stern, Pamela Strein, Kay Gunnar Stubenrauch, Jan van de Winkel, Martine van Vugt: Nucleic acid molecules encoding anti-P-selectin antibodies. Hoffmann La Roche, George W Johnston, Dennis P Tramaloni, Brian C Remy, July 13, 2010: US07754867 (5 worldwide citation)

This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suff ...


7
Simona M Ceccarelli, Odile Chomienne, Patrizio Mattei, Ulrike Obst Sander: Sulfonamide derivatives. Hoffman La Roche, George W Johnston, Dennis P Tramaloni, Brian C Remy, September 21, 2010: US07799933 (5 worldwide citation)

The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R1, R2, R3, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.


8
Alexander Mayweg, Hans Peter Marty, Werner Mueller, Robert Narquizian, Werner Neidhart, Philippe Pflieger, Stephan Roever: CB 1 receptor inverse agonists. Hoffmann La Roche, George W Johnston, Dennis P Tramaloni, Brian C Remy, November 13, 2007: US07294644 (4 worldwide citation)

The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, m and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modul ...


9
Edward Boyd, Frederick Brookfield, Jonathan Gridley, Matthias Koerner, Manfred Kubbies, Raymond Lau, Ulrike Reiff, Georg Tiefenthaler, Wolfgang von der Saal, Timothy Woodcock: Styrylsulfonamides. Hoffmann La Roche, George W Johnston, Patricia S Rocha Tramaloni, Brian C Remy, April 24, 2007: US07208526 (4 worldwide citation)

The present invention relates to the compounds of formula I: their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of such co ...


10
Rainer Haag, Ulrike Leser Reiff, Anja Limberg, Michael Weidner, Gerd Zimmermann: N-monoacylated derivatives of o-phenylenediamines, their analogs and their use as pharmaceutical agents. Hoffmann La Roche, George W Johnston, Patricia S Rocha Tramaloni, Brian C Remy, September 20, 2005: US06946462 (4 worldwide citation)

New compounds represented by the formula or pharmaceutically acceptable salts or prodrugs thereof, wherein X1 and X2 are each independently selected from a CH group or a nitrogen atom; and R is an optionally substituted five or six membered nonaromatic carbocyclic ring or a nonaromatic or aromatic h ...