1
Henry K Tom, Gerald L Rowley: Concentrating zone method in heterogeneous immunoassays. Syva Company, Bertram I Rowland, December 28, 1982: US04366241 (765 worldwide citation)

Method and apparatus are provided for performing immunoassays employing a device comprising a relatively small test zone referred to as an immunosorbing zone, and a relatively large liquid absorbing zone in liquid receiving relationship with said immunosorbing zone. The immunosorbing zone includes a ...


2
David J Litman, Zvi Harel, Edwin F Ullman: Macromolecular environment control in specific receptor assays. Syva Company, Bertram I Rowland, June 23, 1981: US04275149 (636 worldwide citation)

Method and compositions are provided for performing protein binding assays involving a homologous pair consisting of ligand and receptor for the ligand. The method employs a label conjugated to a member of said homologous pair and a uniformly dispersed discontinuous phase of discrete particles in a ...


3
Stanley Falkow, Stephen L Moseley: Specific DNA probes in diagnostic microbiology. Board of Regents of the University of Washington, Bertram I Rowland, November 9, 1982: US04358535 (495 worldwide citation)

Method and compositions for infectious disease diagnosis and epidemiology involving labeled nucleotide probes complementary to nucleic acid coding for a characteristic pathogen product. Clinical isolates are cultivated, expanding the number of microorganisms, the resulting colonies lysed, the genome ...


4
Edward T Maggio: Kit for carrying out chemically induced fluorescence immunoassay. Syva Company, Bertram I Rowland, July 7, 1981: US04277437 (378 worldwide citation)

A competitive protein binding method is provided for the determination of an analyte which is a member of an immunological pair consisting of ligand and receptor for the ligand. A chemiluminescent source is employed comprised of one or more individual members, one chemiluminescent source member bein ...


5
Vernon G Wong, Frank Kochinke: Biocompatible ocular implants. Oculex Pharmaceuticals, Bertram I Rowland, August 22, 1995: US05443505 (332 worldwide citation)

Implants comprising active agents are employed for introduction into a suprachoroidal space or an avascular region of an eye for therapeutic purposes. The administration of drags is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outsi ...


6
Christine K Shewmaker, Jean C Kridl, William R Hiatt, Vic Knauf: Anti-sense regulation of gene expression in plant cells. Calgene, Barbara Rae Venter, Bertram I Rowland, April 21, 1992: US05107065 (318 worldwide citation)

Regulation of expression of genes encoded for in plant cell genomes is achieved by integration of a gene under the transcriptional control of a promoter which is functional in the host and in which the transcribed strand of DNA is complementary to the strand of DNA that is transcribed from the endog ...


7
Stanley N Cohen, Herbert W Boyer: Process for producing biologically functional molecular chimeras. Board of Trustees of the Leland Stanford Jr University, Bertram I Rowland, December 2, 1980: US04237224 (309 worldwide citation)

Method and compositions are provided for replication and expression of exogenous genes in microorganisms. Plasmids or virus DNA are cleaved to provide linear DNA having ligatable termini to which is inserted a gene having complementary termini, to provide a biologically functional replicon with a de ...


8
Vernon G Wong: Biodegradable ocular implants. Visionex, Bertram I Rowland, November 17, 1992: US05164188 (281 worldwide citation)

Encapsulated agents are employed for introduction into the suprachoroid of an eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.


9
Ann Tsukamoto, Charles M Baum, Yukoh Aihara, Irving Weissman: Human hematopoietic stem cell. SyStemix, Bertram I Rowland, October 29, 1991: US05061620 (272 worldwide citation)

Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hema ...


10
Vernon G Wong: Biodegradable ocular implants. Visionex, Bertram I Rowland, March 5, 1991: US04997652 (265 worldwide citation)

Encapsulated drugs are employed for introduction into the chambers of the eye for therapeutic purposes. The administration of drugs is controlled and maintained for long periods of time, while ensuring the substantial absence of significant levels outside the site of administration.