1
Theeuwes Felix, Higuchi Takeru: Osmatic dispensing device for releasing beneficial agent. Alza Corporation, Sabatine Paul L, Mandell Edward L, Benz William H, November 5, 1974: US3845770 (1481 worldwide citation)

A wall surrounding and forming a compartment for containing a useful composition of matter and having a passageway for dispensing the composition is disclosed. The wall is comprised in at least a part of a material permeable to an external fluid. The composition is soluble in the fluid and exhibits ...


2
Ramwell Peter W: Erodible intrauterine device. Alza Corporation, Sabatine Paul L, Benz William H, Mandell Edward L, June 10, 1975: US3888975 (103 worldwide citation)

An intrauterine device for administering drug locally to the uterus at a controlled rate for a prolonged period of time is disclosed. The device contains a body of polymer capable of bioeroding in the environment of the uterus over a prolonged period of time. This body has the drug dispersed through ...


3
Shell John W: Ophthalmic dosage form, for releasing medication over time. ALZA Corporation, Sabatine Paul L, Benz William H, Mandell Edward L, October 21, 1975: US3914402 (74 worldwide citation)

A dosage form for ophthalmic drugs is disclosed. The dosage form is a suspension of 10 to 300 micron particles in a liquid medium. The particles are made up of drug enclosed within a drug release rate-controlling material which bioerodes in the environment of the eye.


4
Michaels Alan S: Bioerodible drug delivery device. Alza Corporation, Sabatine Paul L, Benz William H, Mandell Edward L, February 18, 1975: US3867519 (60 worldwide citation)

A drug delivery device for the continuous and controlled administration of a predetermined therapeutically effective dosage of drug to a mamallian patient over a prolonged period of time. The device meters the flow of drug by means of a drug release rate controlling material comprised of an anionic ...


5
Zaffaroni Alejandro: Intrauterine contraceptive anti-fertility device for the management of reproduction. Alza Corporation, Sabatine Paul L, Mandell Edward L, Benz William H, November 5, 1974: US3845761 (59 worldwide citation)

An intrauterine contraceptive delivery device for administering an anti-fertility agent at a controlled rate for a prolonged period of time is comprised of a shaped body having a cross member and a depending member defining a 'T.' The body is comprised of a wall surrounding at least one reservoir co ...


6
Higuchi Takeru, Hussain Anwar: Intrauterine device for managing the reproductive process. Alza Corporation, Sabatine Paul L, Mandell Edward L, Benz William H, September 9, 1975: US3903880 (40 worldwide citation)

Drug-delivery device for releasing a drug at a continuous and controlled rate for a prolonged period of time is comprised of a shaped body of polymeric material containing a pharmaceutically acceptable drug and permeable to passage of the drug by diffusion. The polymeric material is an ethylene-viny ...


7
Buckles Richard G, Yum Su Il: Self powered device for delivering beneficial agent. ALZA Corporation, Sabatine Paul L, Mandell Edward L, Benz William H, June 18, 1974: US3817248 (39 worldwide citation)

A self powered device for the continuous and controlled delivery of an agent over a prolonged period of time to an agent receptor is disclosed. The device is comprised of a pressure distendable receptacle formed of an elastic material, with the receptacle communicating with a discharge port having a ...


8
Dawson Daniel J, Rudinger Josef: Food containing non-toxic food coloring compositions and a process therefor. Dynapol, Benz William H, November 18, 1975: US3920855 (35 worldwide citation)

Food containing nontoxic coloring compositions which comprise optically chromophoric groups attached via sulfonamido linkages to nondegradable chemical molecules which substantially prevent their absorption from the gastrointestinal tract and find primary applications as food colors.


9
Manautou Jorge Martinez, Garcia Adolfo Rosado: Article for detecting the fertile period and method for using same. Alza Corporation, Sabatine Paul L, Mandell Edward L, Benz William H, April 1, 1975: US3875013 (19 worldwide citation)

An article of manufacture and a test is provided for detecting the fertile period or the presence of pregnancy in the female. The article is comprised of a porous support impregnated with at least one color developing compound such as p-nitrophenyl-n-acetyl-.beta.-d-glucosaminide and at least one bu ...


10
Zaffaroni Alejandro: Biotransformable intrauterine device. Alza Corporation, Sabatine Paul L, Mandell Edward L, Benz William H, August 12, 1975: US3898986 (13 worldwide citation)

An improved intrauterine device which delivers a predetermined therapeutically effective dosage of drug locally to the uterus over a defined period of time is disclosed. The device is initially of a uterine-retentive shape. The device is characterized by undergoing a structural biotransformation in ...