1
Thomas C Maley, Paul A D Orazio, Bonnie C Dalzell, Peter G Edelman, James E Flaherty, Richard W Mason, Robert R McCaffrey: Electrochemical sensors. Ciba Corning Diagnostics, Nicholas I Slepchuk Jr, Arthur S Morgenstern, Judith A Roesler, February 27, 1996: US05494562 (593 worldwide citation)

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


2
Robert McCaffrey, Katarina Tkacik, Brian Holman, James Flaherty, Josef Brown, Peter Edelman: Sensors for measuring analyte concentrations and methods of making same. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, January 13, 1998: US05707502 (397 worldwide citation)

A sensor for measuring a concentration of an analyte in a solution. The sensor comprises a substrate layer, an electrode layer and an immobilized enzyme layer. The sensor further includes an enzyme/polymer layer and/or a hydrophobic layer. The enzyme/polymer layer includes an enzyme disposed within ...


3
James E Flaherty, Robert B Green, Steven C Lepke, Richard W Mason: Sensor package. Ciba Corning Diagnostics, Judith A Roesler, Arthur S Morgenstern, December 10, 1996: US05582698 (272 worldwide citation)

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


4
Masuo Aizawa, Brenda D Manning, Miki Hidaka, Laura S Uretsky: Homogeneous amperometric immunoassay. Nicholas I Slepchuk Jr, Arthur S Morgenstern, March 30, 1993: US05198367 (258 worldwide citation)

A method is described for measuring the amount of analyte present in a sample containing the analyte using a homogeneous amperometric immunoassay. The analyte is covalently bonded to a suitable carrier molecule, which is also covalently bonded to an electroactive molecule. The electroactive molecule ...


5
Joseph S Foos, Peter G Edelman, James E Flaherty, Joseph Berger: Electrochemical sensors. Ciba Corning Diagnostics, Ciba-Geigy, Nicholas I Slepchuk Jr, Arthur S Morgenstern, Judith A Roesler, March 28, 1995: US05401376 (252 worldwide citation)

An electrochemical sensor having a substrate, conductive strips deposited on the substrate, and a layer insulating portions of the conductive strips except those portions which define a working electrode and at least one second electrode. A solid electrolyte contacting the electrodes is covered by a ...


6
Paul A D Orazio, David Sogin: Three-layered membrane for use in an electrochemical sensor system. Chiron Diagnostics Corporation, Arthur S Morgenstern, Gerry A Blodgett, Robert P Blackburn, June 30, 1998: US05773270 (224 worldwide citation)

A system for electrochemical measurement of glucose concentration in an undiluted test sample, e.g. blood is provided containing a sensor including a three-layered contiguous membrane. The membrane has a thickness of 50 to 130 microns, and is composed of a 1 to 10 micron thick first layer, a 10 to 3 ...


7
Thomas C Maley, Mark W Boden, Paul A D Orazio, Peter G Edelman: Glucose and lactate sensors. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, June 23, 1998: US05770028 (214 worldwide citation)

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


8
Thomas C Maley, Paul A D Orazio, Bonnie C Dalzell, Peter G Edelman, James E Flaherty, Richard W Mason, Robert R McCaffrey: Electrochemical sensors. Ciba Corning Diagnostics, Judith A Roesler, Arthur S Morgenstern, February 11, 1997: US05601694 (195 worldwide citation)

A solid shale, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


9
Thomas C Maley, Paul A D Orazio, Bonnie C Dalzell, Peter G Edelman, James E Flaherty, Richard W Mason, Robert R McCaffrey: Electrochemical sensors membrane. Chiron Diagnostics Corporatiion, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, January 27, 1998: US05711868 (173 worldwide citation)

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion ...


10
Robert McCaffrey, Bonnie Dalzell, Katarina Tkacik, Susan Holbert, Mark Boden, James Flaherty, Michael Flanagan, Josef Brown, Kimiya Takeshita, Peter Edelman: Multilayer enzyme electrode membranes and methods of making same. Chiron Diagnostics Corporation, Arthur S Morgenstern, Stanley Sacks, Robert P Blackburn, December 9, 1997: US05696314 (170 worldwide citation)

An electrochemical sensor is designed for use in detecting a concentration of an analyte in a sample solution. The sensor to have a longer useful lifetime, improved stability and improved response time for single or multiple use applications. In one aspect, some of these goals are achieved by provid ...