1
Roger DiPaolo
Nathan K Weiner, Patrick J Odoy, Eric Schultz, Mark Jones, James T Overbeck, Herman DeWeerd, David A Stura, Albert K Bukys, Tim J Woolaver, Thomas P Regan, David Bradbury, Eric E McKenzie, Roger DiPaolo, Christopher Miles, Joel M Katz, Oleinik Ovod Ksenia: System and method for scanning of probe arrays. Affymetrix, Affymetrix, March 5, 2013: US08391582 (8 worldwide citation)

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical el ...


2
Roger DiPaolo
Nathan K Weiner, Patrick J Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A Stura, Albert Bukys, Tim Woolaver, Thomas P Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel Katz, Ksenia Oleink Ovod: System, method, and product for scanning of biological materials. Affymetrix, Affymetrix, March 17, 2005: US20050057676-A1

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical el ...


3
Roger DiPaolo
Nathan K Weiner, Patrick J Odoy, Eric Schultz, Mark Jones, James Overbeck, Herman Deweerd, David A Stura, Albert Bukys, Tim Woolaver, Thomas P Regan, David Bradbury, Eric Earl McKenzie, Roger DiPaolo, Christopher Miles, Joel Katz, Ksenia Oleink Ovod: System, method, and product for scanning of biological materials. Affymetrix, Affymetrix, June 10, 2010: US20100142850-A1

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical el ...


4
Shoulian Dong, Robert J Lipshutz, David J Lockhart: Complexity management and analysis of genomic DNA. Affymetrix, Wei Zhou, Affymetrix, March 26, 2002: US06361947 (81 worldwide citation)

The present invention provides for novel methods of sample preparation and analysis involving reproducibly reducing the complexity of a nucleic sample. The invention further provides for analysis of the above sample by hybridization to an array which may be specifically designed to interrogate the d ...


5
Ming Hsiu Ho: Methods and computer software products for multiple probe gene expression analysis. Affymetrix, Affymetrix, January 7, 2003: US06505125 (30 worldwide citation)

Methods and computer software products are provided for analyzing gene expression data. In one embodiment, the expression of a gene is determined by multiple probes in several experiments. A principal component analysis is performed to obtain the relative expression of the gene in these experiments.


6
David J Lockhart, Chao Qiang Lai, Kevin L Gunderson: Even length proportional amplification of nucleic acids. Affymetrix, Affymetrix, December 17, 2002: US06495320 (10 worldwide citation)

The even length proportional amplification of nucleic acids can increase the amount of nucleic acids while preserving the relative abundance of the individual nucleic acid species, or portions thereof, in the original sample. An even length proportionally amplified nucleic acid preparation may be an ...


7
Peter J Coassin, Jack D McNeal, David E Helphrey: Analytical biochemistry system with robotically carried bioarray. Affymetrix, Affymetrix, September 25, 2012: US08273304 (8 worldwide citation)

An analytical biochemistry system featuring a substrate with reactants immobilized thereon at fixed, known locations, a holder supporting the substrate and a manipulator for transporting the holder to a fixed sample and to an inspection station. The reactants are binding agents for a target biomolec ...


8
David Balaban: Computer software products for nucleic acid hybridization analysis. Affymetrix, Affymetrix, January 21, 2003: US06510391 (7 worldwide citation)

Methods and computer software products are provided for analyzing gene expression data. In one embodiment, multiple probes are used to detect a single transcript. The hybridization intensities of each probe is adjusted by dividing the intensities by the affinities of the probes. The minimal adjusted ...


9
Hui Wang: Methods for monitoring the expression of alternatively spliced genes. Affymetrix, Affymetrix, August 8, 2006: US07089121 (6 worldwide citation)

Methods, probe arrays and computer software products are provided for determining the arrangement of sequence elements. In one embodiment, methods for making and using exon chips are provided. The exon chips may be used to identify and quantify splice variants.


10
Melvin Yamamoto, Clifford A Oostman Jr, John S Sze, Keith S Pearson, Philip C Trenholme, Dan Liu, Chi Sou Yu: Automated method of manufacturing polyer arrays. Affymetrix, Affymetrix, February 18, 2014: US08652774 (4 worldwide citation)

The present invention provides methods to process multiple sensors by providing a sensor plate and HT plates. In a preferred embodiment of the invention, methods for assembling microarray pegs and microarray plates are described for high throughput microarray processing.