1
Jans Eugeen Marie Jozef, Kiekens Filip René Irena, Voorspoels Jody Firmin Marceline, Faure Anne, Arkenau Maric Elisabeth, Barnscheid Lutz, Bartholomäus Johannes, Frevel Marc, Galia Eric, Ziegler Iris: Pharmaceutical dosage form. Grünenthal, Jans Eugeen Marie Jozef, Kiekens Filip René Irena, Voorspoels Jody Firmin Marceline, Faure Anne, Arkenau Maric Elisabeth, Barnscheid Lutz, Bartholomäus Johannes, Frevel Marc, Galia Eric, Ziegler Iris, BÜLLE Jan, July 30, 2009: WO/2009/092601 (28 worldwide citation)

The invention relates to a pharmaceutical dosage form, preferably with controlled release of a pharmacoiogicaiiy active compound (A) contained therein, the pharmaceutical dosage form very preferably being tamper-resistant and most preferably having a breaking strength B1 of at least 500 N in directi ...


2
Arkenau Maric Elisabeth, Bartholomäus Johannes, Ziegler Iris, Haupts Marcel: (De) Darreichungsform mit erschwertem missbrauch, (En) Pharmaceutical form with impeded abuse. Grünenthal, Arkenau Maric Elisabeth, Bartholomäus Johannes, Ziegler Iris, Haupts Marcel, KUTZENBERGER Helga, September 12, 2008: WO/2008/107149 (26 worldwide citation)

(EN) The present invention relates to a multiparticulate pharmaceutical form with impeded abuse including at least one active ingredient with the potential for abuse (A), at least one synthetic or natural polymer (C), optionally at least one natural, semi-synthetic, or synthetic wax (D), at least on ...


3
Ziegler Iris, Jacobs Irwin: (De) Beschichtete pellets, (En) Coated pellets. Grünenthal, Ziegler Iris, Jacobs Irwin, BÜLLE Jan, June 19, 2008: WO/2008/071407 (4 worldwide citation)

(EN) The invention relates to coated pellets which comprise an active pharmaceutical ingredient which is slightly soluble in water, release at least 80% of the active ingredient under in vitro conditions in phosphate buffer at pH 5.0 after 30 minutes, and are bioequivalent to a solution formulation ...


4
Bartholomäus Johannes, Ziegler Iris: (De) 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol enthaltendes arzneimittel mit verzögerter wirkstofffreisetzung, (En) Pharmaceutical containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol and providing delayed release of the active ingredient. Grünenthal, Bartholomäus Johannes, Ziegler Iris, GRÜNENTHAL, May 1, 2003: WO/2003/035053 (4 worldwide citation)

(EN) The invention relates to a pharmaceutical formulation which is characterised by delayed release of the active ingredient. Said formulation contains 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol or one of its pharmaceutically acceptable salts in a matrix with delayed release of the active in ...


5
Bartholomäus Johannes, Ziegler Iris: (De) 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol enthaltendes arzneimittel mit verzögerter wirkstoffreisetzung, (En) Pharmaceutical containing 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol and providing delayed release of the active ingredient. Grünenthal, Bartholomäus Johannes, Ziegler Iris, May 1, 2003: WO/2003/035054 (4 worldwide citation)

(EN) The invention relates to a pharmaceutical formulation which is characterised by delayed release of the active ingredient. Said formulation contains 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol or one of its pharmaceutically acceptable salts in a matrix with delayed release of the active in ...


6
Bartholomäus Johannes, Ziegler Iris: (De) Orale darreichungsformen, (En) Oral dosage forms. Grünenthal, Bartholomäus Johannes, Ziegler Iris, March 8, 2001: WO/2001/015667 (4 worldwide citation)

(EN) The invention relates to oral dosage forms with controlled total-release of an active substance. Said active substance is present in the form of at least two different salts that are present in the dosage form in a solid state of aggregation and that release said active substance in vitro diffe ...


7
Ziegler Iris, Bartholomäus Johannes, Schateikis Dieter: (De) Schmelzformulierte, multipartikuläre orale darreichungsform enthaltend clavulans äure, (En) Melt-formulated, multi-particulate oral dosage form. Grünenthal, Ziegler Iris, Bartholomäus Johannes, Schateikis Dieter, sKUTZENBERGER Helga, March 17, 2005: WO/2005/023216 (1 worldwide citation)

(EN) The invention relates to a melt-formulated, multi-particulate oral dosage form containing clavulanic acid and/or at least one physiologically compatible salt thereof, and one or more sucrose fatty acid esters and, optionally, additional physiologically compatible adjuvants. The invention also r ...


8
Ziegler Iris Dr, Bartholomäus Johannes Dr, Redmer Jessica: (De) Schnell freisetzende darreichungsformen für antibiotika, (En) Fast release dosage forms for antibiotics. Grünenthal, Ziegler Iris Dr, Bartholomäus Johannes Dr, Redmer Jessica, KUTZENBERGER Helga, July 6, 2006: WO/2006/069920 (1 worldwide citation)

(EN) The invention relates to a multi-particulate pharmaceutical dosage form containing at least one antibiotic, which is difficult to wet with aqueous media and which is poorly soluble in aqueous media, and a combination consisting of carrageenan and tricalcium phosphate and, optionally, sucrose es ...


9
Stickel Anita, Ziegler Iris: Hand-held saw, air driven by rodless piston drive cylinder.. Stickel Anita, Ziegler Iris, March 16, 1994: EP0586737-A1

A hand-held air-driven saw, for stone materials among other things, has a reciprocating saw blade (2) which is driven by a rodless pneumatic cylinder having an inner plunger piston (1). The saw blade (2) is flexibly attached to a slide (6) externally guided by the pneumatic cylinder. The back of the ...


10
Ziegler Iris, Bartholomäus Johannes: (De) Retardierte, orale, pharmazeutische darreichnungsformen, (En) Oral pharmaceutical forms of administration with a delayed action. Grünenthal, Ziegler Iris, Bartholomäus Johannes, March 8, 2001: WO/2001/015681

(EN) The invention relates to oral pharmaceutical forms of administration with an at least partially delayed action. The pharmaceutical active agent contained in said forms of administration, tramadol, is at least partially in the form of a compound formed in situ with a water solubility $m(F) 100 m ...