1
Yan John, Sirhan Motasim, Cryer Brett, Bhat Vinayak D: Degradable implantable medical devices. Elixir Medical Corporation, Yan John, Sirhan Motasim, Cryer Brett, Bhat Vinayak D, HESLIN James M, October 12, 2006: WO/2006/108065 (34 worldwide citation)

Devices and methods are provided for an implantable medical device which is degradable over a clinically relevant period of time. The medical devices may have the form of implants, graft implants, vascular implants, non vascular implants, wound closure implants, sutures, drug delivery implants, biol ...


2
Bhat Vinayak D, Yan John: Devices delivering therapeutic agents and methods regarding the same. Avantec Vascular Corporation, Bhat Vinayak D, Yan John, BAINS Nena, February 5, 2004: WO/2004/010900 (29 worldwide citation)

Devices and methods for reducing, inhibiting, or treating restenosis and hyperplasia after intravascular intervention are provided. In particular, the present invention provides luminal prosthesis (13), which allow for sustained or controlled release of at least one therapeutic capable agent (28) wi ...


3
Yan John, Huang Howard, Bhat Vinayak D: Luminal prostheses and methods for coating thereof. Elixir Medical Corporation, Yan John, Huang Howard, Bhat Vinayak D, HESLIN James M, May 2, 2008: WO/2008/051867 (6 worldwide citation)

Luminal prostheses comprise scaffolds having coatings adhered to at least a portion of their outer surfaces. The surfaces are modified to enhance binding of the coatings. For example, the surfaces may be microblasted, laser treated, chemically etched, exposed to plasma, or exposed to a corona discha ...


4
Yan John, Du Yong, Symmon Bruce E: Multi-chip module and method of manufacture. Spansion, Yan John, Du Yong, Symmon Bruce E, DRAKE Paul S, November 2, 2006: WO/2006/115649 (5 worldwide citation)

A multi-chip module (10) and a method for manufacturing the multi-chip module (10). A first semiconductor chip (40) is mounted to a support substrate (12) and a second semiconductor chip (50) is mounted to the first semiconductor chip (40). The second semiconductor chip (50) has a smaller dimension ...


5
Yan John, Zheng Xiaoxia, Bhat Vinayak D: Macrocyclic lactone compounds and methods for their use. Elixir Medical Corporation, Yan John, Zheng Xiaoxia, Bhat Vinayak D, sKEZER William B, March 20, 2008: WO/2008/033956 (3 worldwide citation)

The present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula (I) wherein R1, R2, R3, R5, R6 and R8 are each independently a member selected from the group consisting of H, C1-6 alkyl and OH; R4, R7 and R9 are each indepe ...


6
ZHENG Xiaoxia, YAN John, BHAT Vinayak: ENDOPROTHÈSES BIODÉGRADABLES ET LEURS PROCÉDÉS DE FABRICATION, BIODEGRADABLE ENDOPROSTHESES AND METHODS FOR THEIR FABRICATION. ELIXIR MEDICAL CORPORATION, ZHENG Xiaoxia, YAN John, BHAT Vinayak, HESLIN James M, January 3, 2013: WO/2013/003644 (3 worldwide citation)

The disclosure provides biodegradable implantable devices such as a stent comprising a biodegradable polymeric wherein the polymeric material is treated to control crystallinity and/or Tg. The stent is capable to expand at body temperature from a crimped configuration to a deployed diameter and have ...


7
Zheng Xiaoxia, Yan John, Bhat Vinayak: Biodegradable endoprostheses and methods for their fabrication. Elixir Medical Corporation, Zheng Xiaoxia, Yan John, Bhat Vinayak, HESLIN James M, July 24, 2008: WO/2008/089434 (3 worldwide citation)

Biodegradable endoprostheses are formed from amorphous polymers having desirable biodegradation characteristics. The strength of such amorphous polymers is enhanced by annealing to increase crystallinity without substantially increasing the biodegradation time.


8
Sirhan Motasim, Yan John: Delivery of therapeutic capable agents. Avantec Vascular Corporation, Sirhan Motasim, Yan John, BAINS Nena, July 25, 2002: WO/2002/056790 (2 worldwide citation)

A device and a method using the same, for reducing restenosis and hyperplasia after intravascular intervention. In particular, the present invention provides luminal prostheses which allow for controlled release of at least one therapeutic capable agent with increased efficacy to selected locations ...


9
YAN John, ZHENG Xiaoxia, BHAT Vinayak D: COMPOSÉS MACROCYCLIQUES À BASE DE LACTONE ET LEURS PROCÉDÉS DUTILISATION, MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE. ELIXIR MEDICAL CORPORATION, YAN John, ZHENG Xiaoxia, BHAT Vinayak D, HESLIN James M, April 12, 2012: WO/2012/047813 (2 worldwide citation)

The present disclosure provides a device for intracorporeal use which comprises an implant or a temporary device and at least one source of myolimus or a derivative thereof. The present disclosure also provides a method of inhibiting cell proliferation, inflammation or cytokine production by systemi ...


10
Sirhan Motasim, Yan John: Apparatus and methods for variably controlled substance delivery from implanted prostheses. Avantec Vascular Corporation, Sirhan Motasim, Yan John, BAINS Nena, May 8, 2003: WO/2003/037223 (1 worldwide citation)

The present invention provides improved stents and other prostheses for delivering substances to vascular and other luminal and intracorporeal environments. In particular, the present invention provides luminal prostheses (13) which allow for programmed and controlled substance delivery protocols fo ...