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Stéphane De Lombaert
BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M: INHIBITEURS OXADIAZOLE DE PRODUCTION DE LEUCOTRIÈNES, OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M, MORRIS Michael P, March 29, 2012: WO/2012/040137

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases an ...


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Zindell Renee M, Riether Doris, Thomson David S, Wu Lifen: Compounds which modulate the cb2 receptor. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Zindell Renee M, Riether Doris, Thomson David S, Wu Lifen, MORRIS Michael P, October 18, 2007: WO/2007/118041 (22 worldwide citation)

Compounds are provided which bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, the compounds having the general formula (I) wherein R¿1?, R¿2?, R¿3?, X and Ar have the meanings given in the specification, and the preparation and use thereof. The compounds are valuable CB ...


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Cirillo Pier Francesco, Thomson David S, Riether Doris, Berry Angela, Wu Lifen, Hickey Eugene Richard: Compounds which modulate the cb2 receptor. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Cirillo Pier Francesco, Thomson David S, Riether Doris, Berry Angela, Wu Lifen, Hickey Eugene Richard, MORRIS Michael P, May 29, 2008: WO/2008/064054 (6 worldwide citation)

Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.


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Chen Zhidong, Cirillo Pier Francesco, Disalvo Darren, Liu Weimin, Marshall Daniel Richard, Wu Lifen, Young Erick Richard Roush: Substituted 3-amino-thieno[2,3-b] pyridine-2-carboxylic acid amide compounds as ikk inhibitors. Boehringer Ingelheim Pharmaceuticals, Chen Zhidong, Cirillo Pier Francesco, Disalvo Darren, Liu Weimin, Marshall Daniel Richard, Wu Lifen, Young Erick Richard Roush, MORRIS Michael P, June 23, 2005: WO/2005/056562 (2 worldwide citation)

Disclosed are compounds of formula (I): wherein the variables R1, R2, R3 and Z are described herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases infla ...


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Cirillo Pier Francesco, Hickey Eugene Richard, Riether Doris, Wu Lifen, Zindell Renee, Amouzegh Patricia, Ermann Monika, Walker Edward: Diazepane compounds which modulate the cb2 receptor. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Cirillo Pier Francesco, Hickey Eugene Richard, Riether Doris, Wu Lifen, Zindell Renee, Amouzegh Patricia, Ermann Monika, Walker Edward, MORRIS Michael P, April 30, 2009: WO/2009/055357 (2 worldwide citation)

Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.


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Gao Donghong Amy, Moss Neil, Wang Ji, Wu Jiang Ping, Wu Lifen, Xiong Zhaoming: Cytokine inhibitors. Boehringer Ingelheim Pharmaceuticals, Gao Donghong Amy, Moss Neil, Wang Ji, Wu Jiang Ping, Wu Lifen, Xiong Zhaoming, MORRIS Michael P, March 9, 2006: WO/2006/026235

Disclosed are compounds of formula (I) which inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compound ...