1
Arnaiz Damian O, Chou You Ling, Kochanny Monica J, Lee Wheeseong, Lu Shou Fu, Mengel Anne, Phillips Gary, Wei Guo Ping, Yu Hongyi: Piperidine derivatives as antagonists of the cc chemokine receptor ccr1 and their use as anti-inflammatory agents. Schering Aktiengesellschaft, Arnaiz Damian O, Chou You Ling, Kochanny Monica J, Lee Wheeseong, Lu Shou Fu, Mengel Anne, Phillips Gary, Wei Guo Ping, Yu Hongyi, June 29, 2006: WO/2006/066948 (32 worldwide citation)

Piperidine derivatives of the following formulae (I) and (II) and their pharmaceutically acceptable salts, which are functional antagonists of the CC chemokine receptor CCR1 and are thus useful as anti inflammatory agents, a pharmaceutical compositions containing said piperidine derivatives or their ...


2
Davey David, Lee Wheeseong, Lu Shou Fu, Phillips Gary, Wei Guo Ping, Ye bin: Benzylether amine compounds useful as ccr-5 antagonists. Schering Aktiengesellschaft, Davey David, Lee Wheeseong, Lu Shou Fu, Phillips Gary, Wei Guo Ping, Ye bin, HERMENAU Ronald S, May 26, 2005: WO/2005/047249 (20 worldwide citation)

The present invention relates to compounds which are CCR-5 receptor antagonists of the general formula (I) wherein R1, R2, R3, R4, Ra, Rb, Rc, Rd, X, m and n are as defined herein. The invention further comprises pharmaceutical compositions comprising such compounds, as well as the use of such compo ...


3
Dunning Laura, Jaroch Stefan, Kochanny Monica J, Lee Wheeseong, Lian Xiongdong, Liang Meina, Lu Shou Fu, Onuffer James, Phillips Gary, Wei Guo Ping, Ye bin: Substituted quinoline ccr5 receptor antagonists. Schering Aktiengesellschaft, Dunning Laura, Jaroch Stefan, Kochanny Monica J, Lee Wheeseong, Lian Xiongdong, Liang Meina, Lu Shou Fu, Onuffer James, Phillips Gary, Wei Guo Ping, Ye bin, HERMENAU Ronald S, January 8, 2004: WO/2004/002960 (18 worldwide citation)

The present invention relates to CCR5 receptor antagonists of formulae (1a) or (1b), enantiomers, diastereomers, salts and solvates thereof wherein R1, R2, R3, R4, R5, and R7 are as defined herein. The invention further includes a method of CCR5-mediated disorders employing such compounds.


4
Bryant Judi, Buckman Brad, Islam Imadul, Mohan Raju, Morrissey Michael, Wei Guo Ping, Xu Wei, Yuan Shendong: 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists. Schering Aktiengesellschaft, Bryant Judi, Buckman Brad, Islam Imadul, Mohan Raju, Morrissey Michael, Wei Guo Ping, Xu Wei, Yuan Shendong, HERMENAU Ronald S, June 24, 2004: WO/2004/052366 (10 worldwide citation)

Compounds of formula (I), where m, n, R1, R2, R3, R4 and R6 are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, methods of using these compounds as antithrombotic agents and processes for synthesizing these compoun ...


5
Arnaiz Damian, Davey David, Guilford William, Cleve Arwed, Kirkland Thomas, Claret Emmanuel, Khim Seock Kyu, Brown Greg, Ye bin, Vogel David, Light David, Liang Amy, Kochanny Monica, Wei Guo Ping, Parkinson John: Diamine derivatives as inhibitors of leukotriene a4 hydrolase. Bayer Schering Pharma Aktiengesellschaft, Arnaiz Damian, Davey David, Guilford William, Cleve Arwed, Kirkland Thomas, Claret Emmanuel, Khim Seock Kyu, Brown Greg, Ye bin, Vogel David, Light David, Liang Amy, Kochanny Monica, Wei Guo Ping, Parkinson John, LARSON Jacqueline, July 12, 2007: WO/2007/079078 (6 worldwide citation)

This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxid ...


6
Davey David D, Mohan Raju, Phillips Gary B, Wei Guo Ping, Xu Wei: 1-substituted imidazole derivatives as nos inhibitors. Schering Aktiengesellschaft, Davey David D, Mohan Raju, Phillips Gary B, Wei Guo Ping, Xu Wei, SHAW Melissa A, November 13, 2003: WO/2003/092678

N-heterocyclic derivatives of the following formula: (I) where m, n, p, A1, R1, R2, R3 and R4 are described herein, as useful as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and pr ...


7
Bryant Judi A, Buckman Brad O, Islam Imadul, Mohan Raju, Morrissey Michael M, Wei Guo Ping, Xu Wei, Yuan Shendong: (naphthaline) Platelet adenosine diphosphate receptor antagonists. Schering Aktiengesellschaft, Bryant Judi A, Buckman Brad O, Islam Imadul, Mohan Raju, Morrissey Michael M, Wei Guo Ping, Xu Wei, Yuan Shendong, ZELANO Antony J Millen White Zelano Arlington Courthouse Plaza 1 2200 Clarendon Boulevard Suite 1400 Arlington VA 22201, December 12, 2002: WO/2002/098856

Compounds of the following formula (I): where a, b, R?1¿, R?2¿, R?3¿, R?4¿ and R?6¿ are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, methods of using these compounds as antithrombotic agents and processes for sy ...


8
Chen Ming, Claret Emmanuel, Cleve Arwed, Davey David, Guilford William, Khim Seock Kyu, Kirkland Thomas, Kochanny Monica, Liang Amy, Light David, Parkinson John, Vogel David, Wei Guo Ping, Ye bin, Ye Hong: Amide inhibitors of leukotriene a4 hydrolase. Bayer Schering Pharma Aktiengesellschaft, Chen Ming, Claret Emmanuel, Cleve Arwed, Davey David, Guilford William, Khim Seock Kyu, Kirkland Thomas, Kochanny Monica, Liang Amy, Light David, Parkinson John, Vogel David, Wei Guo Ping, Ye bin, Ye Hong, LARSON Jacqueline, July 12, 2007: WO/2007/079003

This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4a, R4b, R4c, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, R9 and R10 are described herein, or pharmaceutically acceptable salts, solvates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydro ...


9
WANG Xueqing, MEYER Michael, YAO Betty, GUO Tao, WEI Guo Ping Robert, WANG Lijuan Jane: [fr] ANTAGONISTES DES RÉCEPTEURS DE CHIMIOKINES, [en] CHEMOKING RECEPTOR ANTAGONISTS. WANG Xueqing, MEYER Michael, YAO Betty, GUO Tao, WEI Guo Ping Robert, WANG Lijuan Jane, Abbott Laboratories, ABBOTT LABORATORIES TRADING, CHINA PATENT AGENT, January 24, 2013: WO/2013/010453

[en] Disclosed herein are chemokine receptor antagonists of formula (I) wherein G1, X1, X2, and X3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.