Mitchell Dombrowski, Robert Welch: Digital dispenser. Wayne State University, Reising Ethington Barnard Perry & Milton, September 25, 1990: US04959056 (100 worldwide citation)

A digital dispenser aid device (10) of the type for use with a syringe (12) includes a housing (24). The syringe (12) can be fixedly mounted within a chamber (28) within the housing (24). A body member 54 includes a recessed portion (56) retaining the cap portion (22) of a plunger (20) therein. The ...

Robert J Levis, Louis J Romano: Method for analyzing an organic sample. Wayne State University, Brooks & Kushman, May 11, 1993: US05210412 (87 worldwide citation)

Described is a method and apparatus for analyzing an organic sample. In the preferred embodiment, this method and apparatus allows the determination of the base sequence of a nucleic acid by determining the molecular weights of the components of a biological sample. The method uses either a pre-exis ...

Roy S Sundick, Lily A Jones, David I Smith: Chicken interleukin-15 and uses thereof. Wayne State University, Darby & Darby, May 18, 2004: US06737522 (83 worldwide citation)

The present invention pertains to isolated DNA encoding avian interleukin-15 and to purified interleukin-15 polypeptides.

J Richard Spears, Philip S Levin, Paul J Zalesky: High pressure perfusion device. Therox, Wayne State University, Pennie & Edmonds, August 25, 1998: US05797876 (75 worldwide citation)

The present invention includes a guidewire device capable of delivering perfusion fluids to a vascular site while at the same time exhibiting handling characteristics associated with existing non-perfusion guidewires. Preferred embodiments include a perfusion guidewire which closely matches the dime ...

Michael H Lehmann: Tachycardia detection for automatic implantable cardioverter/defibrillator with atrial and ventricular sensing capability. Wayne State University, Reising Ethington Barnard Perry & Milton, August 29, 1989: US04860749 (71 worldwide citation)

An automatic tachycardia detection assembly to be implanted in a person for stimulating the heart upon detection of abnormal tachycardias. The assembly includes an atrial sensor (16) and ventricular sensor (18) for sensing activity within the atria and ventricles of the heart, respectively. Also inc ...

Pan Zhuo Hua, Dizhoor Alexander M: Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids. Wayne State University, Pennsylvania College Of Optometry, Pan Zhuo Hua, Dizhoor Alexander M, BROWDY Roger L, November 15, 2007: WO/2007/131180 (69 worldwide citation)

Nucleic acid vectors encoding light-gated cation-selective membrane channels, in particular channelrhodopsin-2 (Chop2), converted inner retinal neurons to photosensitive cells in photoreceptor- degenerated retina in an animal model. Such treatment restored visual perception and various aspects of vi ...

Vincent Divino Jr, Seth A Foerster, James M Gessert, Robert A Mest, Paul J Zalesky, James Richard Spears: Method for the preparation and delivery of gas-enriched fluids. TherOx, Wayne State University, Margaret A Kivinski, January 13, 2004: US06676900 (66 worldwide citation)

A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that re ...

Lawrence D Favro, Robert L Thomas, Pao Kuang Kuo, Li Chen: Confocal microscope. The Board of Governors of Wayne State University, Dykema Gossett, November 10, 1992: US05162941 (64 worldwide citation)

A confocal microscope comprises a focusing lens for focusing a light source onto a pin hole. The use of the lens for this purpose, when used within a confocal microscope apparatus, greatly reduces image artifacts and creates an increased transfer efficiently between the light source and the sample.

James R Spears: Apparatus and method for making a diffusing tip in a balloon catheter system. Wayne State University, Brooks & Kushman, September 6, 1994: US05344419 (63 worldwide citation)

An apparatus and method are disclosed for making a laser balloon catheter (10) having a diffusing tip (24) for propagating a uniform cylindrical pattern of laser energy. Included in the catheter are an elongated flexible tube (12) with an inflatable balloon (14) connected to the tube and means for i ...

J Richard Spears, Philip S Levin, Paul J Zalesky, Vincent Divino Jr: Angioscopy apparatus and methods. Therox, Wayne State University, Fletcher Yoder & Van Someren, September 26, 2000: US06123698 (63 worldwide citation)

The present invention includes a fluid delivery device capable of delivering perfusion or other fluids to a vascular site. Preferred embodiments permit delivery of large quantities of fluid without causing recoil of the device, and without causing trauma to the vascular site.