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Eyre David R: Methods of detecting collagen degradation -i(in vivo).. Washington Res Found, September 16, 1992: EP0502928-A1 (25 worldwide citation)

Methods of determining collagen degradation in vivo, by quantitating the concentration of a peptide in a body fluid, the peptide being a C-terminal type II collagen telopeptide containing a hydroxylysyl pyridinoline cross-link or a type III collagen telopeptide containing a hydroxylysyl pyridinoline ...


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Agabian Nina, Stephens Richard, Kuo Cho Chou, Mullenbach Guy T: Chlamydia major outer membrane protein.. Chiron, Washington Res Found, August 27, 1986: EP0192033-A2 (22 worldwide citation)

Methods and compositions are provided for the production of a polypeptide which is immunologically cross-reactive with a naturally-occurring major outer membrane protein (MOMP) of Chlamydia trachomatis. A DNA construct including a replication system recognized by E. coli, and an MOMP gene under the ...


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Martin Roy W, Silverstein Fred E: Endoscopically deliverable ultrasound imaging system.. Washington Res Found, September 28, 1988: EP0284055-A2 (17 worldwide citation)

An endoscopically deliverable ultrasound imaging system having an ultrasound probe mounted at the end of an endoscopically deliverable catheter (6). The catheter (6) connects the probe to an ultrasound imaging system. The axial or radial position of the ultrasound probe is measured by a position tra ...


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Fischer Edmond H, Krebs Edwin G, Tonks Nicholas K, Cool Deborah E: Methods and compositions for the treatment of malignancies in which a protein kinase is associated.. Washington Res Found, December 30, 1992: EP0520029-A1 (2 worldwide citation)

Methods and compositions are disclosed for the treatment of malignancies in which a protein tyrosine kinase is associated. The malignancies may be treated with a gene transfer vehicle capable of infecting malignant cells, wherein the gene transfer vehicle carries a DNA construct comprising a DNA seq ...


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Eyre David R: Methods of detecting collagen degradation in vivo. Washington Res Found, November 15, 1995: EP0682256-A1 (1 worldwide citation)

The invention provides a method of determining type II or type III collagen degradation, comprising quantitating in a body fluid, optionally urine, blood, serum or synovial fluid, the concentration of at least a first 3-hydroxypyridinium cross-linked type II or type III collagen telopeptide.


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Eyre David R: Assaying for collagen degradation in vivo. Washington Res Found, January 13, 1999: EP0890840-A2 (1 worldwide citation)

The invention involves the use of an immunological binding partner in assaying for type I collagen degradation by examining binding of the immunological binding partner when contacted with a body fluid sample, which immunological binding partner is characterised by binding to both: (i) a first telop ...


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Grayston Thomas J, Kuo Cho Chou, Wang San Pin, Campbell Lee Ann: Detection of a unique chlamydia strain associated with acute respiratory disease.. Washington Res Found, January 5, 1994: EP0577144-A1 (1 worldwide citation)

Methods for detecting a unique strain of Chlamydia associated with acute respiratory disease. These methods utilize monoclonal antibody directed against an antigenic determinant of the TWAR organism, or DNA probes capable of specifically hybridizing to at least a portion of the DNA sequence of the T ...