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Leamon Christopher Paul, Wang Yu, Vlahov Iontcho Radoslavov, You Fei, Kleindl Paul Joseph, Santhapuram Hari Krishna R: Conjugates containing hydrophilic spacer linkers. Endocyte, Leamon Christopher Paul, Wang Yu, Vlahov Iontcho Radoslavov, You Fei, Kleindl Paul Joseph, Santhapuram Hari Krishna R, BALL Rebecca L, December 31, 2008: WO/2009/002993 (38 worldwide citation)

Described herein are compositions and methods for use in targeted drug delivery using cell- surface receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations.


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Kanazawa Ichiro, Liu Wanzhao, Wang Yu Lai, Wada Keiji, Goto Jun, Murata Miho: (Ja) ハンチンチン遺伝子の発現抑制, (En) Inhibition of the expression of huntington gene. Japan Science and Technology Agency, Kanazawa Ichiro, Liu Wanzhao, Wang Yu Lai, Wada Keiji, Goto Jun, Murata Miho, HIROTA Masanori, November 25, 2004: WO/2004/101787 (22 worldwide citation)

(EN) It is intended to provide a method of inhibiting the expression of a Huntington gene by using a double-stranded RNA (dsRNA); a Huntington gene expression inhibitor to be used in the inhibition of the expression of a Huntington gene as described above; and a drug for preventing and/or treating H ...


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Vlahov Iontcho Radoslavov, Leamon Christopher Paul, Wang Yu: Binding ligand linked drug delivery conjugates of tubulysins. Endocyte, Vlahov Iontcho Radoslavov, Leamon Christopher Paul, Wang Yu, BALL Rebecca L, September 18, 2008: WO/2008/112873 (19 worldwide citation)

Described herein are compounds, pharmaceutical compositions and methods for treating pathogenic cell populations. The compounds described herein include conjugates of tubulysins and vitamin receptor binding ligands. The conjugates also include a releasable bivalent linker.


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Vlahov Iontcho Radoslavov, Wang Yu, Leamon Christopher Paul: Tubulysins and processes for preparing. Endocyte, Vlahov Iontcho Radoslavov, Wang Yu, Leamon Christopher Paul, MCLAREN Kevin L, April 30, 2009: WO/2009/055562 (17 worldwide citation)

Processes are described for the preparation of tubulysins. The processes are useful for preparing predetermined mixtures of tubulysins, preparing single tubulysins from mixtures of tubulysins, and for converting one tubulysin into a different tubulysin. The tubulysins described herein are useful in ...


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Wang Yu: Aseptic producing container for bean sprouts and its technology. Wang Yu, chen xiuwen, January 22, 2003: CN01122213 (13 worldwide citation)

The present invention relates to aseptic bean sprouts producing container and its sterilizing technology. The present invention aims at eliminating the demerits of using chemical disinfectant. The container consists of support board with water draining hole, plastic film tube inside vertical enclosu ...


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VLAHOV Iontcho Radoslavov, GROANING Michael, KLEINDL Paul Joseph, SANTHAPURAM Hari Krishna R, YOU Fei, WANG Yu, XU Le cun, STANFORD Katheryn Marie, RITTER Allen, LEAMON Christopher Paul: Procédés de préparation de tubulysines, Processes for preparing tubulysins. Endocyte, VLAHOV Iontcho Radoslavov, GROANING Michael, KLEINDL Paul Joseph, SANTHAPURAM Hari Krishna R, YOU Fei, WANG Yu, XU Le cun, STANFORD Katheryn Marie, RITTER Allen, LEAMON Christopher Paul, BALL Rebecca L, February 9, 2012: WO/2012/019123 (8 worldwide citation)

Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.


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Wang Yu Wei, Matherson Kevin, Sobol Robert: Camera sensor correction. Hewlett Packard Development Company, Wang Yu Wei, Matherson Kevin, Sobol Robert, Limon Jeff Et Al, November 26, 2009: WO/2009/142641 (7 worldwide citation)

Systems and methods for camera sensor correction are disclosed. In an exemplary embodiment, a method may include sampling a spectral response for a plurality of color channels at different spatial locations on a sensor. The method may also include applying a 4x4 color correction matrix at the differ ...


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Wang Yu Chin: Health eyepiece for correcting error in the refractive power of the eyes. Wang Yu Chin, January 20, 1993: GB2257633-A (4 worldwide citation)

An eyepiece the lenses of which being made from a mesh which is made from a compound containing carbon, lead, tin and sodium and, the spectacle frame of which being made from a compound containing permanent magnet powder, ceramic powder, carbon fiber, carbon, lead, tin and sodium. The eyepiece produ ...


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Froland Wayne A, Kelner Drew N, Dumas Michael L, Pan Clark, Whelan James, Wang Yu Chang John, Wang Wei: (pacap) Receptor (vpac2) agonists and their pharmacological methods of use. Bayer Pharmaceuticals Corporation, Froland Wayne A, Kelner Drew N, Dumas Michael L, Pan Clark, Whelan James, Wang Yu Chang John, Wang Wei, GREENMAN Jeffrey M, January 22, 2004: WO/2004/006839 (4 worldwide citation)

This invention provides novel peptides that function in vivo as agonists of the VPAC2 receptor. These insulin secretagogue polypeptides are shown to lower blood glucose in vivo more than controls upon glucose challenge. The polypeptides of this invention are also stable in formulation and have long ...