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Raboisson Pierre Jean Marie Bernard, de, Kock Herman Augustinus, Vendeville Sandrine Marie Helene, Hu Lili, Van de, Vreken Wim, Mc, Gowan David Craig, Tahri Abdellah, Surleraux Dominique Louis Nestor Ghislain, Simmen Kenneth Alan: Macrocylic inhibitors of hepatitis c virus. Tibotec Pharmaceuticals, Raboisson Pierre Jean Marie Bernard, de, Kock Herman Augustinus, Vendeville Sandrine Marie Helene, Hu Lili, Van de, Vreken Wim, Mc, Gowan David Craig, Tahri Abdellah, Surleraux Dominique Louis Nestor Ghislain, Simmen Kenneth Alan, DAELEMANS Frank, February 8, 2007: WO/2007/014919 (63 worldwide citation)

Inhibitors of HCV of formula (I), and the N-oxides, salts, and stereochemically isomeric forms thereof, wherein R1 is aryl or a saturated, a partially unsaturated or completely unsaturated 5 or 6 membered monocyclic or 8 to 12 membered bicyclic heterocyclic ring system containing one nitrogen, and o ...


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Raboisson Pierre Jean Marie Bernard, de, Kock Herman Augustinus, Mc, Gowan David Craig, Van de, Vreken Wim, Hu Lili, Tahri Abdellah, Vendeville Sandrine Marie Helene: Macrocyclic inhibitors of hepatitis c virus. Tibotec Pharmaceuticals, Raboisson Pierre Jean Marie Bernard, de, Kock Herman Augustinus, Mc, Gowan David Craig, Van de, Vreken Wim, Hu Lili, Tahri Abdellah, Vendeville Sandrine Marie Helene, WANTE Dirk, May 22, 2008: WO/2008/059046 (35 worldwide citation)

Inhibitors of HCV replication of Formula (I) and the salts and stereoisomers thereof, wherein each dashed line (represented by - - - - -) represents an optional double bond; X is N, CH and where X bears a double bond it is C; R1 is -OR7, -NH-SO2R8; R2 is hydrogen, and where X is C or CH, R2 may also ...


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Kesteleyn Bart Rudolf Romanie, Raboisson Pierre Jean Marie, Van de, Vreken Wim, Canard Maxime Francis Jean Marie Ghislain: 1, 5, 6-substituted-2-oxo-3-cyano-1, 6a-diaza-tetrahydro-fluoranthenes as anti-infective agents. Tibotec Pharmaceuticals, Kesteleyn Bart Rudolf Romanie, Raboisson Pierre Jean Marie, Van de, Vreken Wim, Canard Maxime Francis Jean Marie Ghislain, WANTE Dirk, July 13, 2006: WO/2006/072636 (1 worldwide citation)

HIV inhibitory compounds of formula: (I) salts and stereoiso mers thereof, wherein R1 and R2 are hydrogen or optionally substituted C1-10alkyl; R3 is: (a) n is 1, 2 or 3; R3a is nitro, cyano, amino, halo, hydroxy, C1-4alkyloxy, hydroxycarbonyl, aminocarbonyl, C1-4alkyloxycarbonyl, mono- or di(C1-4al ...