1
Mccarthy Jeanette, Ableson Alan: Diagnosis and treatment of vascular disease. Vitivity, Mccarthy Jeanette, Ableson Alan, SMITH DeAnn F, February 27, 2003: WO/2003/016494 (3 worldwide citation)

The present invention is based at least in part on the discovery of polymorphisms within the integrin beta 3 (ITGB3), von Willebrand factor (VWF), endothelin receptor type B (EDNRB), factor 2 (F2), P-selectin (SELP), thrombospondin 1 (THBS1), and thrombospondin 2 (THBS2) genes. Accordingly, the inve ...


2
Jeanette McCarthy: Methods and compositions for identifying risk factors for abnormal lipid levels and the diseases and disorders associated therewith. Vitivity, Millennium Pharmaceuticals, March 4, 2004: US20040043389-A1

The present invention is based at least in part on the discovery of associations between polymorphic regions and specific diseases or disorders, e.g., abnormal lipid levels, e.g., abnormally low HDL-C levels, or diseases or disorders associated with abnormal lipid levels, e.g., vascular or metabolic ...


3
Jeanette McCarthy, George Q Daley, Stacey Bolk Gabriel: Diagnosis and treatment of vascular disease. Vitivity, Lahive & Cockfield, May 22, 2003: US20030096248-A1

The present invention is based at least in part on the discovery of polymorphisms within the thrombospondin 1 (THBS1) and thrombospondin 4 (THBS4) genes. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of a THBS1 or THBS4 gene. The invent ...


4
Jeanette McCarthy: Methods and compositions for identifying risk factors for abnormal lipid levels and the diseases and disorders associated therewith. Vitivity, Millennium Pharmaceuticals, February 5, 2004: US20040023225-A1

The present invention is based, at least in part, on the identification of associations between polymorphic regions of the CD36L1 gene and specific diseases or disorders, e.g., abnormal lipid levels, e.g., abnormally high TG level or an abnormally high TG:HDL-C ratio, or diseases or disorders associ ...


5
Jeanette McCarthy, Alan Ableson: Diagnosis and treatment of vascular disease. Vitivity, Lisa M Dirocco Esq, May 15, 2003: US20030092013-A1

The present invention is based at least in part on the discovery of polymorphisms within the integrin beta 3 (ITGB3), von Willebrand factor (VWF), endothelin receptor type B (EDNRB), factor 2 (F2), P-selectin (SELP), thrombospondin 1 (THBS 1), and thrombospondin 2 (THBS2) genes. Accordingly, the inv ...


6
Jeanette McCarthy: Diagnosis and treatment of vascular disease. Vitivity, Lahive & Cockfield, July 31, 2003: US20030143544-A1

The present invention is based at least in part on the discovery of polymorphisms within the endothelin-1 (EDN1) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of an EDN1 gene. The invention also provides methods for identifying sp ...


7
Jeanette McCarthy: Diagnosis and treatment of vascular disease. Vitivity, Lahive & Cockfield, October 2, 2003: US20030187335-A1

The present invention is based at least in part on the discovery of a polymorphism within the interleukin 1 receptor antagonist (IL1RN) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of an IL1RN gene. The invention also provides me ...


8
Jeanette McCarthy: Diagnosis and treatment of vascular disease. Vitivity, Lahive & Cockfield, May 8, 2003: US20030087244-A1

The present invention is based at least in part on the discovery of polymorphisms within the Factor VII (F7) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of an F7 gene. The invention also provides methods for identifying specific ...


9
Jeanette McCarthy: Diagnosis and treatment of vascular disease. Vitivity, Lahive & Cockfield, May 29, 2003: US20030099957-A1

The present invention is based at least in part on the discovery of polymorphisms within the Factor 2 (F2) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an allelic variant of an F2 gene. The invention also provides methods for identifying specific a ...


10
Jeanette McCarthy: Diagnosis and treatment of vascular disease. Vitivity, Lahive & Cockfield, May 29, 2003: US20030099958-A1

The present invention is based at least in part on the discovery of polymorphisms within the thrombospondin 2 (THBS2) gene, the angiotensin converting enzyme 1 (ACE), and the beta fibrinogen (FGB) gene. Accordingly, the invention provides nucleic acid molecules having a nucleotide sequence of an all ...