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Scott William J, Dumas Jacques, Boyer Stephen, Lee Wendy, Chen Yuanwei, Phillips Barton, Verma Sharad, Chen Jianqing, Chen Zhi, Fan Jianmei, Raudenbush Brian, Redman Aniko, Yi Lin, Zhu Qingming: Novel cyanopyridine derivatives useful in the treatment of cancer and other disorders. Bayer Pharmaceuticals Corporation, Scott William J, Dumas Jacques, Boyer Stephen, Lee Wendy, Chen Yuanwei, Phillips Barton, Verma Sharad, Chen Jianqing, Chen Zhi, Fan Jianmei, Raudenbush Brian, Redman Aniko, Yi Lin, Zhu Qingming, TRAVERSO Richard J, September 16, 2004: WO/2004/078747 (36 worldwide citation)

This invention relates to novel diaryl ureas of Formula (I), pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper­proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.


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KNIGHT Steven David, MILLER William Henry, NEWLANDER Kenneth Allen, VERMA Sharad Kumar: INDOLES, INDOLES. GLAXOSMITHKLINE, KNIGHT Steven David, MILLER William Henry, NEWLANDER Kenneth Allen, VERMA Sharad Kumar, PENG Tony W, June 7, 2012: WO/2012/075080 (29 worldwide citation)

Herein are disclosed azaindazoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.


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Dumas Jacques, Lee Wendy, Chen Yuanwei, Adnane Lila, Scott William J, Verma Sharad, Chen Jianging, Chen Zhi, Yi Lin: Substituted pyridine derivatives useful in the treatment of cancer and other disorders. Bayer Pharmaceuticals Corporation, Dumas Jacques, Lee Wendy, Chen Yuanwei, Adnane Lila, Scott William J, Verma Sharad, Chen Jianging, Chen Zhi, Yi Lin, TRAVERSO Richard J, September 16, 2004: WO/2004/078128 (23 worldwide citation)

This invention relates to novel diaryl ureas of formula I wherein A is phenyl, naphthyl, mono- or bi-cyclic heteroaryl, or a group of the formula B is phenyl, naphthyl, or pyridyl, L is a bridging group Q is: (1) C(S)NR4R5; (2) C(O)NR7-NR4R5; (3) tetrazolyl; (4) imidazolyl; (5) imidazoline-2-yl; (6) ...


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Zhang Chengzhi, Dumas Jacques, Zhu Qingming, Smith Roger, Liu Qingjie, Verma Sharad, Duquette Jason, Zhao Qian, Fan Dongping, Bondar Georgiy, Coish Philip: Novel heterocycles. Bayer Pharmaceuticals Corporation, Zhang Chengzhi, Dumas Jacques, Zhu Qingming, Smith Roger, Liu Qingjie, Verma Sharad, Duquette Jason, Zhao Qian, Fan Dongping, Bondar Georgiy, Coish Philip, GREENMAN Jeffrey M, March 2, 2006: WO/2006/023843 (5 worldwide citation)

The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.