1
Galla Chandra Rao, Christopher Larson, Madeline Repollet, Herman Rutner, Leon W M M Terstappen, Shawn Mark O Hara, Steven Gross: Analysis of circulating tumor cells, fragments, and debris. Veridex, January 4, 2011: US07863012 (36 worldwide citation)

The methods and reagents described in this invention are used to analyze circulating tumor cells, clusters, fragments, and debris. Analysis is performed with a number of platforms, including flow cytometry and the CellSpotterĀ® fluorescent microscopy imaging system. Analyzing damaged cells has shown ...


2
Mark Carle Connelly, Gerald V Doyle, Galla Chandra Rao, Leon W M M Terstappen: Method for assessing disease states by profile analysis of isolated circulating endothelial cells. Veridex, March 8, 2011: US07901950 (33 worldwide citation)

Elevated number of Circulating Endothelial Cells (CEC) have been implicated in disease conditions associated with the formation or destruction of blood vessels such as acute coronary syndrome, thrombocytopenic purpura, sickle cell disease, sepsis, lupus, nephrotic syndromes, rejection of organ trans ...


3
Yixin Wang: Cancer diagnostic panel. Veridex LCC, Todd F Volyn, March 25, 2008: US07348142 (31 worldwide citation)

A method of diagnosing cancer by identifying differential modulation of each gene (relative to the expression of the same genes in a normal population) in a combination of genes selected from two groups of genes. Gene expression portfolios and kits for employing the method are further aspects of the ...


4
Michael Kagan, Galla Chandra Rao, Jerry Prohaska, Tor Alden: Cartridge for containing a specimen sample for optical analysis. Veridex, October 19, 2010: US07815863 (30 worldwide citation)

An improved cartridge for holding a fluid sample with a small volume is disclosed herein. The cartridge has a test chamber and a vestibule through which the test fluids are inserted into the test chamber. Improved grips are flared-out to aid manipulation. The handle portion is reinforced to prevent ...


5
Frank A W Coumans, Jan Greve, Frank P Modica, Leon W M M Terstappen, Arjan G J Tibbe, John A Verrant: Methods and algorithms for cell enumeration in a low-cost cytometer. Veridex, Johnson & Johnson, Joseph F Aceto Esq, July 27, 2010: US07764821 (29 worldwide citation)

The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applications the cost, size and complexity ...


6
Richard L Columbus: Cartridge for containing a specimen sample for optical analysis. Veridex, October 20, 2009: US07604777 (20 worldwide citation)

A cartridge for holding a test specimen with an extremely small volume. The cartridge has a test chamber and a vestibule through which the test fluids are inserted into the test chamber. The cartridge has a stopper having a pair of seals, the first of which seals the test chamber inlet between the v ...


7
Arjan Tibbe, Jan Greve, Dhanesh Gohel, Erik Droog, Leon W M M Terstappen: Methods and algorithms for cell enumeration in low-cost cytometer. Veridex, May 17, 2011: US07943397 (20 worldwide citation)

The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applications the cost, size and complexity ...


8
Tycho M Scholtens, Leon L M M Terstappen, Arjan G J Tibbe: Magnetic separation apparatus and methods. Veridex, February 23, 2010: US07666308 (20 worldwide citation)

Apparatuses and methods for separating, immobilizing, and quantifying biological substances from within a fluid medium. Biological substances are observed by employing a vessel (6) having a chamber therein, the vessel comprising a transparent collection wall (5). A high internal gradient magnetic ca ...


9
Arjan G J Tibbe, Leon W M M Terstappen: Method and apparatus for imaging target components in a biological sample using permanent magnets. Veridex, November 9, 2010: US07828968 (18 worldwide citation)

A system for enumeration of cells in fluids by image cytometry is described for assessment of target populations such as leukocyte subsets in different bodily fluids or bacterial contamination in environmental samples, food products and bodily fluids. Briefly, fluorescently labeled target cells are ...


10
Erik Droog, Dhanesh Gohel, Arjan G J Tibbe, Jan Greve, Leon W M M Terstappen: Methods and algorithms for cell enumeration in a low-cost cytometer. Veridex, March 6, 2012: US08128890 (17 worldwide citation)

The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applications the cost, size and complexity ...