1
Darwin J Prockop, Loretta D Spotila, Constantinos D Deltas, Larisa Sereda, Andrea Westerhausen Larson, Michael Pack, Alain Colige, James Early, Jarmo Körkkö, Leena Ala Kokko, Susanna Annunen, Tero Pihlajamaa, Mirko Vuoristo, Petteri Paassilta: Compositions and methods for detecting altered COL1A1 gene sequences. Allegheny University of the Health Sciences, Thomas Jefferson University, University of Oulu, Morgan Lewis & Bockius L, July 24, 2001: US06265157 (7 worldwide citation)

Compositions and methods useful for determining whether a subject has an alteration in a gene encoding a protein chain of Type I or Type IX collagen are described. Novel intronic sequences of five human genes, COL1A1, COL1A2, COL9A1, COL9A2, and COL9A3 are described. Methods of determining the exist ...


2
Lloyd Ruddock, Feras Hatahet: Method for producing disulfide bond containing proteins in a prokaryotic cytoplasm. University of Oulu, Berggren, August 16, 2016: US09416388

The present invention relates to a method for producing natively folded disulfide bond containing proteins in a prokaryotic host. The method comprises that in the cytoplasm of a prokaryotic cell is expressed protein(s) of interest that naturally contain disulfide bonds and naturally occurring or inv ...


3
Anne Heikkinen, Hongmin Tu, Taina Pihlajaniemi: Method for diagnosing diseases. University of Oulu, Dodds & Associates, Leea S Somersalo, John Dodds, August 17, 2010: US07776556

An improved method for diagnosing autoimmune or genetic diseases is provided in this disclosure. In particular, a method to diagnose diseases affecting the tissues of organs selected from the group of spleen, brain, heart, kidney, thyroid, eye, skin, intestine, liver, pancreas, adrenal gland, prosta ...


4
Anne Heikkinen, Hongmin Tu, Taina Pihlajaniemi: Method for diagnosing diseases. University of Oulu, Dodds & Associates, September 18, 2008: US20080227105-A1

An improved method for diagnosing autoimmune or genetic diseases is provided in this disclosure. In particular, a method to diagnose diseases affecting the tissues of organs selected from the group of spleen, brain, heart, kidney, thyroid, eye, skin, intestine, liver, pancreas, adrenal gland, prosta ...


5
Raili Myllylä, Heli Ruoisalainen: Pharmaceutical product. University of Oulu, Dodds & Associates, May 20, 2010: US20100124548-A1

The present invention relates to methods and products for the treatment of any disorder or condition, which is associated with abnormal amount of non-collagenous protein, or abnormal oligomerization or dysfunction of non-collagenous protein, such as adiponectin in the blood circulation and/or tissue ...


6
Lloyd Ruddock: Method for Producing Natively Folded Proteins in a Prokaryotic Host. University Of Oulu, August 9, 2012: US20120202245-A1

The present invention relates to a method for producing a protein of interest containing one or more disulfide bonds in its native state. The method comprises that a prokaryotic host cell is genetically engineered to express the protein of interest and a sulfhydryl oxidase in the cytoplasm of the ho ...


7
Suntio Teuvo, Tenno Robert, Tenno Ander: Method and apparatus for soft-sensor characterization of batteries. Helsinki University Of Technology, Suntio Teuvo, Tenno Robert, Tenno Ander, University Of Oulu, KUOSMANEN Panu, June 12, 2003: WO/2003/049211

A method and apparatus are disclosed for simulating the operation of a rechargeable battery. There is obtained (503, 553) a value for at least one parameter that describes an internal state of the battery. Said obtained value is used for calculating (504, 505, 554, 555) a prediction value for a char ...


8
TEJESVI MYSORE V: New polypeptides from endophytes of empetrum nigrum and their fragments, encoding them, their production and uses. UNIVERSITY OF OULU, Seppo Laine Oy, September 22, 2011: WO/2011/113999

The present invention relates to novel polypeptides and fragments thereof, and novel polypeptides and fragments for use in therapy, particularly as an antimicrobial agent. The invention also relates to a new method for isolating genes encoding microbial metabolites and nucleic acids encoding the pol ...


9
Method for Improving Penetration or Long Term Adhesion of Compositions to Dental Tissues and Compositions Usable in Said Method. University of Oulu, February 20, 2014: US20140050674-A1

This invention concerns a method of improving penetration of compositions to dentin, enamel, dental pulp or cement and dental compositions for restoration or decoration of teeth, for use in pulp medication comprising, for root canal disinfection and/or obturation and for desensitizing. This inventio ...


10
Method for producing disulfide bond containing proteins in a prokaryotic cytoplasm. UNIVERSITY OF OULU, November 20, 2014: US20140342398-A1

The present invention relates to a method for producing natively folded disulfide bond containing proteins in a prokaryotic host. The method comprises that in the cytoplasm of a prokaryotic cell is expressed protein(s) of interest that naturally contain disulfide bonds and naturally occurring or inv ...



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