1
Paul Ashton, Peter Anthony Crooks, Tadeusz Cynkowski, Grazyna Cynkowska, Hone Guo: Means to achieve sustained release of synergistic drugs by conjugation. University Of Kentucky Research Foundation, McDermott Will & Emery, April 18, 2000: US06051576 (307 worldwide citation)

A codrug composition of at least two drug compounds covalently linked to one another via a labile bond to form a single codrug composition, or ionically linked to one another to form a single workings composition, and methods of use of the codrug for the treatment of various medical conditions. The ...


2
Ottfried J Hahn: Method and apparatus for conversion of coal in situ. University of Kentucky Research Foundation, King and Schickli, October 11, 1988: US04776638 (298 worldwide citation)

A method for the electro-thermal and electrochemical underground conversion of coal into oil and by-products comprises the steps of inserting an underground probe into a bore hole until the probe is in close proximity to a coal seam. A mixture of air, steam, an electrolyte and a suitable catalyst is ...


3
Patrick P DeLuca, Motoko Kanke, Toyomi Sato, Hans G Schroeder: Porous microspheres for drug delivery and methods for making same. The University of Kentucky Research Foundation, Burns Doane Swecker & Mathis, April 4, 1989: US04818542 (237 worldwide citation)

Controlled release drug delivery systems comprised of spherical microporous polymeric network of interconnecting channels containing pore incorporated drugs or other agents wherein the drugs or agents are confined within the pore channel are described. Also disclosed are processing parameters in con ...


4
Thomas J Smith, Paul Ashton, Paul A Pearson: Sustained release drug delivery devices. University of Kentucky Research Foundation, Burns Doane Swecker & Mathis, January 3, 1995: US05378475 (224 worldwide citation)

A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of ...


5
Craig A Grimes: Remote resonant-circuit analyte sensing apparatus with sensing structure and associated method of sensing. University of Kentucky Research Foundation, Macheledt Bales, March 19, 2002: US06359444 (194 worldwide citation)

A resonant sensing apparatus for operative arrangement within a test environment to sense an analyte. A sensing structure is included having an antenna in electrical communication with a resonant circuit and a structural element made of a material that selectively responds to the analyte. This sensi ...


6
Anwar A Hussain: Method of administering narcotic antagonists and analgesics and novel dosage forms containing same. University of Kentucky Research Foundation, Burns Doane Swecker & Mathis, August 7, 1984: US04464378 (193 worldwide citation)

The invention provides a novel method of administering narcotic antagonists, narcotic analgesics and related compounds, and novel dosage forms containing those compounds which are adapted for nasal administration. The nasal dosage forms disclosed include solutions, suspensions, gels and ointments. E ...


7
Hurst George S, Parks James E: Electrical sensor of plane coordinates. The University of Kentucky Research Foundation, May 9, 1972: US3662105 (191 worldwide citation)

An inexpensive electrical sensor of plane coordinates employs juxtaposed sheets of conducting material having electrical equipotential lines extending across each sheet and arranged normal to each other. A probe upon touching each sheet at a selected intersection of the equipotential lines causes se ...


8
Robert A Lodder, Lisa A Cassis: Apparatus and method for multiple wavelength of tissue. University of Kentucky Research Foundation, King & Schickli, August 15, 1995: US05441053 (185 worldwide citation)

An apparatus for analyzing the chemical composition of tissue includes a near infrared light source, a fiber-optic probe, a mechanism for directing the light from the light source onto the tissue and detectors for detecting light reflected by the tissue. The light source transmits an incident beam h ...


9
Paul Ashton, Paul A Pearson: Implantable controlled release device to deliver drugs directly to an internal portion of the body. The University of Kentucky Research Foundation, Lowe Price LeBlanc & Becker, June 30, 1998: US05773019 (175 worldwide citation)

A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that is permeable to the low solubility agent is disclosed. A method for treating a mammal to obtain a desire ...


10
Pedro Moreno, Robert A Lodder, William O&apos Connor, James E Muller: Methods and apparatus for in vivo identification and characterization of vulnerable atherosclerotic plaques. University of Kentucky Research Foundation, Fish & Richardson P C, November 9, 2004: US06816743 (149 worldwide citation)

Methods and apparatus for analyzing the chemical composition of vulnerable plaques with an intravascular catheter having a near-infrared light source, a fiber-optic probe, a mechanism for directing the light from the light source into a blood vessel, and detectors for detecting light reflected or sc ...



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