1
Martin D Fox: Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a). University of Connecticut, November 29, 1988: US04787888 (581 worldwide citation)

A bandage assembly for percutaneous administration of a medicament generates sonic vibrations to produce sonophoresis. The assembly has a bandage member with a cavity containing a medicament and having a piezoelectric polymer element extending thereacross. An sonic generator is coupled to the piezoe ...


2
Francis Moussy, Robert W Conlan, Markham C Godwin, Richard D Beach: Generic integrated implantable potentiostat telemetry unit for electrochemical sensors. The University of Connecticut, Cantor Colburn, April 2, 2002: US06366794 (570 worldwide citation)

A generic implantable puck that can be used with a number of biosensor configurations. This generic implantable potentiostat telemetry unit (the puck) can also be part of a system to detect glucose concentrations. An electrochemical system partially implantable into a body for detecting glucose conc ...


3
Francis Moussy, Donald Kreutzer, Diane Burgess, Jeffrey Koberstein, Fotios Papadimitrakopoulos, Samuel Huang: Implant coating for control of tissue/implant interactions. The University of Connecticut, Cantor Colburn, December 24, 2002: US06497729 (254 worldwide citation)

A tissue/implant interface, comprising an implant and a bioactive polymer layer adjacent at least a portion of the outer surface of the implant, wherein the polymer layer contains at least one tissue response modifier covalently attached to the polymer layer or entrapped within the polymer layer in ...


4
George Y Wu, Catherine H Wu: Carrier system and method for the introduction of genes into mammalian cells. University of Connecticut, Lahive & Cockfield, November 24, 1992: US05166320 (240 worldwide citation)

A targetable gene delivery system is provided for introducing foreign genes into mammalian cells. The system employs a soluble targetable DNA complex and utilizes receptor-mediated endocytosis to endow cell specificity. The soluble DNA-carrying complex is formed by non-covalently binding a ligand co ...


5
Quing Zhu: Combined ultrasound and near infrared diffused light imaging system. The University of Connecticut, Cantor Colburn, July 24, 2001: US06264610 (191 worldwide citation)

A combined ultrasound and near infrared (NIR) diffused light imaging system includes a combined ultrasound and NIR light probe operatively connected to an ultrasound imaging system and an NIR diffused light imaging system. The combined ultrasound and NIR light probe comprises ultrasound transducer e ...


6
Steven L Goodman, Paul Campagnola: Free-form fabricaton using multi-photon excitation. The University of Connecticut, Cantor Colburn, November 13, 2001: US06316153 (163 worldwide citation)

A method wherein small, two- or three- dimensional structures are formed by multiple-photon-absorbed photopolymerization and/or cross-linking of a precursor composition. Use of multi-photon excitation allows fabrication of structures and structural features having at least one dimension of less than ...


7
Gordon G Carmichael, David B Batt, Zhong Liu: Targeted RNA degradation using nuclear antisense RNA. University of Connecticut, Hamilton Brook Smith & Reynolds P C, June 1, 1999: US05908779 (148 worldwide citation)

The invention pertains to a novel method and construct for regulating gene expression through inhibition of gene expression by nuclear antisense RNA. The construct provides an efficient means for introducing, expressing and accumulating the antisense RNA in the nucleus. The antisense RNA hybridizes ...


8
Gerard L Cote, Martin D Fox, Robert B Northrop: Optical glucose sensor apparatus and method. University of Connecticut, May 11, 1993: US05209231 (138 worldwide citation)

An optically based apparatus for non-invasively determining the concentration of optically active substances in a specimen comprises, a source of a beam of spatially coherent light which is acted upon to produce a rotating linear polarized vector therein. A beam splitter splits the beam into a refer ...


9
Charles J Burstone, A Jon Goldberg: Orthodontic appliance of titanium alloy. University of Connecticut, Prutzman Kalb Chilton & Alix, April 15, 1980: US04197643 (97 worldwide citation)

A beta-titanium alloy wire is used as the force-imparting component in orthodontic appliances. The alloy provides up to a threefold improvement over 18-8 stainless steel wire in load deflection rate and a twofold increase in maximum elastic displacement while providing a low modulus of elasticity an ...


10
A Jon Goldberg, Charles J Burstone: Passive dental appliances of fiber-reinforced composites. The University of Connecticut, Chilton Alix & Van Kirk, January 16, 1990: US04894012 (84 worldwide citation)

Disclosed is a dental appliance system having use as an orthodontic retainer, bridge, space maintainer, splint and the like, the improvement wherein a structural component thereof is formed from an effective fiber-reinforced composite material comprising a polymeric matrix and a reinforcing fiber co ...