1
Hitzeman Ronald A, Hagie Franklin E Iv, Hall Benjamin D, Ammerer Gustav: Expression of polypeptides in yeast.. Univ Washington, Univ Washington, September 15, 1982: EP0060057-A1 (60 worldwide citation)

In order to make a yeast strain capable of expressing a desired polypeptide (e.g. leukocyte interferon D) which it does not normally make or use, it is transformed with an expression vector. This is obtained by producing a transfer vector which has respective origins of replication and phenotypic se ...


2
Callis James B C O Board Of Re, Osten David W C O Minnesota Mi, Carim Hatim M C O Minnesota Mi: Characterizing biological matter in a dynamic condition using near infrared spectroscopy.. Minnesota Mining & Mfg, Univ Washington, March 27, 1991: EP0419223-A2 (44 worldwide citation)

A method is provided for predicting a property of a matter of biological origin, such as biological fluid, containing water, in a dynamic condition where the biological fluid may be approximated to contain two compartments where one compartment has a proportionally larger or smaller amount of water ...


3
Sundsmo John S, Ksander George A, Mcpherson John M, Ross Russel, Sprugel Katherine H: Wound healing composition.. Collagen, Univ Washington, October 28, 1987: EP0243179-A1 (44 worldwide citation)

A soft tissue wound healing composition comprising a mixture of fibrillar collagen, heparin, and an effective amount of a growth, chemotactic or differentiation factor, preferably FGF or PDGF in which the factor may be incorporated as synthetic or purified factor or in the form of undegranulated pla ...


4
Beachy Roger N, Fraley Robert T, Rogers Stephen G: Protection of plants against viral infection.. Monsanto, Univ Washington, May 27, 1987: EP0223452-A2 (35 worldwide citation)

A process for producing genetically transformed plants which are resistant to infection by a plant virus, comprises the steps of: (a) inserting into the genome of a plant cell a recombinant, double-stranded DNA molecule comprising (i) a promoter which functions in plant cells to cause the production ...


5
STAYTON PATRICK S, HOFFMAN ALLAN S, CONVERTINE ANTHONY J, BENOIT DANIELLE, DUVALL CRAIG L, JOHNSON PAUL, GALL ANNA: [fr] Copolymères à deux séquences et complexes polynucléotidiques pour apport dans des cellules, [de] Diblockcopolymere und Polynukleotidkomplexe daraus zur Abgabe in Zellen, [en] Diblock copolymers and polynucleotide complexes thereof for delivery into cells. UNIV WASHINGTON, PHASERX, July 31, 2013: EP2620161-A1 (33 worldwide citation)

[en] Described herein are copolymers, and methods of making and utilizing such copolymers. Such copolymers have at least two blocks: a first block that has at least one unit that is hydrophilic at physiologic pH, and a second block that has hydrophobic groups. This second block further has at least ...


6
Girard Thomas James, Broze George John Jr: Factor x-laci hybrid protein.. Univ Washington, July 31, 1991: EP0439442-A2 (32 worldwide citation)

A single-chain hybrid blood coagulation inhibitor is disclosed which has an amino acid sequence composed of two subsequences corresponding to the light chain of Factor X and LACI's first Kunitz domain.


7
Rutter William J, Valenzuela Pablo D T, Hall Benjamin D, Ammerer Gustav: Synthesis of human virus antigens by yeast.. Univ California, Univ Washington, February 16, 1983: EP0072318-A2 (29 worldwide citation)

The present invention relates to synthesis of HBsAg in yeast. Yeast expression vectors comprising a yeast promoter, ADHI, have been constructed. The region of the HBV genome coding for the S-protein, excluding a possible 163 amino acid presequence, has been transferred to the yeast expression vector ...


8
Schnepf Harry Ernest, Whiteley Helen Riaboff: Plasmids coding for b. thuringiensis crystal protein, their production and their use in creating genetically engineered bacterial strains, the aforesaid strains per se and their use in producing said protein, said protein so-produced, insecticidal formulations comprising the same and a method of producing an insecticidal effect.. Univ Washington, November 3, 1982: EP0063949-A2 (29 worldwide citation)

The crystal protein of Bacillus thuringiensis is an insecticidal substance. Unfortunately growth phase limitations are exhibited by B. thuringiensis in producing this protein. This invention, however, provides a plasmid capable of replication in a bacterial host species and containing expressible he ...


9
Powell Jerry S: Human erythropoietin gene: high level expression in stably transfected mammalian cells.. Univ Washington, February 3, 1988: EP0255231-A1 (26 worldwide citation)

The Apa I restriction fragment of the human erythropoietin gene, for producing high titers of biologically active hormone from stably transfected cell lines.


10
Murray Mark J, Berkner Kathleen L, Foster Donald C, Davie Earl W: Expression of protein c.. Zymogenetics, Univ Washington, March 25, 1987: EP0215548-A1 (26 worldwide citation)

Genomic and cDNA sequences coding for a protein having substantially the same biological activity as human protein C and recombinant transfer vectors comprising these sequences are disclosed. Methods are disclosed for producing a protein which has substantially the same biological activity as human ...