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Thompson John E, Taylor Catherine: Inhibition of apoptosis-specific elf-5a (“eif-5a1”) with antisense oligonucleotides and sirnas as anti-inflammatory therapeutics. Senesco Technologies, Thompson John E, Taylor Catherine, LAVENUE Teresa A, January 27, 2005: WO/2005/007853 (11 worldwide citation)

The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5A1, nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRNAs to inhibit expression of ...


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Thompson John E, Taylor Catherine, Cliché Dominic, Heikkila Elisabeth Margaret, Senchyna Diane Michelle, Flanagan John Gerard: Use of antisense oligonucleotides or sirna to suppress expression of eif-5a1. Senesco Technologies, Thompson John E, Taylor Catherine, Cliché Dominic, Heikkila Elisabeth Margaret, Senchyna Diane Michelle, Flanagan John Gerard, LAVENUE Teressa A, September 16, 2004: WO/2004/078940 (9 worldwide citation)

The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis factor 5A1 or simply factor 5A1, apoptosis factor 5A1 nucleic acids and polypeptides and methods for inhibiting or suppressing apoptosis in cells using antisense nucleotides or siRN ...


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Thompson John E: Isoforms of elf-5a: senescence-induced elf5a; wounding-induced elf-5a; growth elf-5a; and dhs. Senesco Technologies, Thompson John E, LAVENUE Teresa A, December 29, 2004: WO/2004/113528 (5 worldwide citation)

The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ('eIF-5A'): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the ex ...


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Dumbroff Erwin B: Control of senescence in fruits, vegetables and flowers.. Dumbroff Erwin B, Thompson John E, Shih Ching Yu, Stewart Michael Ian, June 28, 1989: EP0321503-A1

Senescence in perishable plant tissue is inhibited by the application thereto of an effective amount of a compound of formula (I), wherein R1, R2, R3, R4 and R5 are each selected from the group consisting of hydrogen, -OH or -OR7, provided that at least one of R1 to R5 is a hydroxyl group, R6 is sel ...


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Dumbroff Erwin B, Thompson John E, Shih Ching Y: Controle de la senescence des fruits, des legumes et des fleurs, Control of senescence in fruits, vegetables and flowers. Dumbroff Erwin B, Thompson John E, University Of Waterloo, Shih Ching Y, University Of Waterloo, SIM & MCBURNEY, October 8, 1991: CA1290162

ABSTRACT OF THE DISCLOSURE Senescence in perishable plant tissue is inhibitedby the application thereto of an effective amount of acompound of the formula: Imagewherein R1, R2, R3, R4 and R5 are each selected from thegroup consisting of hydrogen, -OH or -OR7, provided thatat least one of R1 to R5 is ...


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Thompson John E, Wang Tzann Wei, Lu Dongen Lily: Dna encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5a, transgenic plants and a method for controlling senescence programmed and cell death in plants. Senesco Technologies, Thompson John E, Wang Tzann Wei, Lu Dongen Lily, KING Jennifer L, June 6, 2002: WO/2002/044392

Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhpusine synthase and senesc ...


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Dumbroff Erwin B, Thompson John E, Shih Ching Yu, Stewart Michael Ian: Control of senescence in fruits, vegetables and flowers. Dumbroff Erwin B, Thompson John E, Shih Ching Yu, Stewart Michael Ian, BERKSTRESSER Jerry W, April 21, 1988: WO/1988/002602

Senescence in perishable plant tissue is inhibited by the application thereto of an effective amount of a compound of formula (I), wherein R¿1?, R¿2?, R¿3?, R¿4? and R¿5? are each selected from the group consisting of hydrogen, -OH or -OR¿7?, provided that at least one of R¿1? to R¿5? is a hydroxyl ...


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Schnitzer Jay J, Thompson John E, Wilson Jay M: Microprocessor-controlled ventilator system and methods. Children S Medical Center Corporation, The General Hospital Corporation, Schnitzer Jay J, Thompson John E, Wilson Jay M, VOCK Curtis A, November 20, 1997: WO/1997/042995

A microprocessor controlled ventilator (10) controls a patient's breathing selectively. The ventilator utilizes an intratracheal pulmonary ventilation using a reverse thrust catheter (12) for inspiration, and a microprocessor (22) for selectively controlling the ventilation parameters.