1
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke, Keith A Friedman, Fredric C Colman: Analyte monitoring device and methods of use. Therasense, Merchant & Gould P C, January 16, 2001: US06175752 (1483 worldwide citation)

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing ...


2
Adam Heller, Benjamin J Feldman, James Say, Mark S Vreeke: Method of using a small volume in vitro analyte sensor. Therasense, Merchant & Gould P C, September 19, 2000: US06120676 (1110 worldwide citation)

A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 .mu.L. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. I ...


3
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke: Process for producing an electrochemical biosensor. TheraSense, Merchant & Gould P C, August 15, 2000: US06103033 (1100 worldwide citation)

A process for the manufacture of small sensors with reproducible surfaces, including electrochemical sensors. One process includes forming channels in the surface of a substrate and disposing a conductive material in the channels to form an electrode. The conductive material can also be formed on th ...


4
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke, Keith A Friedman, Fredric C Colman: Analyte monitoring device and methods of use. TheraSense, Merchant & Gould P C, May 20, 2003: US06565509 (1071 worldwide citation)

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing ...


5
Adam Heller, Michael V Pishko: Subcutaneous glucose electrode. TheraSense, Merchant & Gould P C, December 11, 2001: US06329161 (1020 worldwide citation)

A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucoses is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive s ...


6
Adam Heller, Steven H Drucker, Robert Y Jin, Jeffery V Funderburk: Analyte monitoring device and methods of use. TheraSense, Merchant & Gould P C, May 6, 2003: US06560471 (993 worldwide citation)

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing ...


7
Roger T Bonnecaze, Angela C Freeland: Blood analyte monitoring through subcutaneous measurement. TheraSense, Merchant & Gould P C, June 17, 2003: US06579690 (980 worldwide citation)

One embodiment of the invention is a method for obtaining an estimate of an analyte concentration in a first fluid. First, measurements of an analyte concentration in a second fluid are obtained using a sensing device. An analyte concentration estimate in the first fluid is determined from these mea ...


8
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke: Electrochemical analyte sensor. TheraSense, Merchant & Gould P C, November 19, 2002: US06484046 (966 worldwide citation)

An electrochemical analyte sensor having conductive traces on a substrate is used to determine a level of analyte in in vitro or in vivo analyte-containing fluids. The electrochemical analyte sensor includes a substrate and conductive material disposed on the substrate, the conductive material formi ...


9
John Bernard Buse, Alan Charles Moses: Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator. TheraSense, Merchant & Gould P C, July 8, 2003: US06591125 (966 worldwide citation)

A region of skin, other than the fingertips, is stimulated. After stimulation, an opening is created in the skin (e.g., by lancing the skin) to cause a flow of body fluid from the region. At least a portion of this body fluid is transported to a testing device where the concentration of analyte (e.g ...


10
Benjamin J Feldman, Adam Heller, Ephraim Heller, Fei Mao, Joseph A Vivolo, Jeffery V Funderburk, Fredric C Colman, Rajesh Krishnan: Method of manufacturing small volume in vitro analyte sensor. TheraSense, Merchant & Gould P C, September 16, 2003: US06618934 (858 worldwide citation)

A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agen ...