1
Patrick P DeLuca, Motoko Kanke, Toyomi Sato, Hans G Schroeder: Porous microspheres for drug delivery and methods for making same. The University of Kentucky Research Foundation, Burns Doane Swecker & Mathis, April 4, 1989: US04818542 (244 worldwide citation)

Controlled release drug delivery systems comprised of spherical microporous polymeric network of interconnecting channels containing pore incorporated drugs or other agents wherein the drugs or agents are confined within the pore channel are described. Also disclosed are processing parameters in con ...


2
Hurst George S, Parks James E: Electrical sensor of plane coordinates. The University of Kentucky Research Foundation, May 9, 1972: US3662105 (217 worldwide citation)

An inexpensive electrical sensor of plane coordinates employs juxtaposed sheets of conducting material having electrical equipotential lines extending across each sheet and arranged normal to each other. A probe upon touching each sheet at a selected intersection of the equipotential lines causes se ...


3
Paul Ashton, Paul A Pearson: Implantable controlled release device to deliver drugs directly to an internal portion of the body. The University of Kentucky Research Foundation, Lowe Price LeBlanc & Becker, June 30, 1998: US05773019 (195 worldwide citation)

A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that is permeable to the low solubility agent is disclosed. A method for treating a mammal to obtain a desire ...


4
Patrick P DeLuca, Frantisek Rypacek: Biodegradable microspheres as a carrier for macromolecules. The University of Kentucky Research Foundation, Burns Doane Swecker, November 3, 1992: US05160745 (145 worldwide citation)

A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to degrade and release the macromolecular agent at a controlled rate. The method involves emulsifying a vi ...


5
Patrick P De Luca, Frantisek Rypacek: Preparation of biodegradable microspheres useful as carriers for macromolecules. The University of Kentucky Research Foundation, Burns Doane Swecker & Mathis, May 3, 1988: US04741872 (127 worldwide citation)

A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to degrade and release the macromolecular agent at a controlled rate. The method involves emulsifying a vi ...


6
George A Digenis, Dagmar Noskova: Multicompartment hard capsule with control release properties. The University of Kentucky Research Foundation, Lowe Price LeBlanc & Becker, September 30, 1997: US05672359 (64 worldwide citation)

The present invention relates to a hard capsule made from a material such as gelatin, starch or a hydrophilic polymer. The capsule of the present invention is formulated into a delivery system which incorporates pharmacologically active components in three or more distinct compartments. When three c ...


7
David A Pienkowski: Implant having reduced generation of wear particulates. The University of Kentucky Research Foundation, King & Schickli, December 30, 1997: US05702456 (51 worldwide citation)

A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in ...


8
Scott R Hamann: Combined antagonist compositions. The University of Kentucky Research Foundation, McDermott Will & Emery, November 28, 2000: US06153621 (50 worldwide citation)

Novel compositions of a combination of nicotinic, opioid, serotonergic and/or adrenergic antagonists in combination with nicotinic and opioid agonists, anti-depressants, stimulants, non-steroidal anti-inflammatory drugs, and local anesthetics, such combinations being useful in the treatment of excit ...


9
Glenn B Collins, David F Hildebrand, Paul A Lazzeri, Thomas R Adams, Wayne A Parrott, Lynn M Hartweck: Transformation, somatic embryogenesis and whole plant regeneration method for Glycine species. Lubrizol Genetics, The University of Kentucky Research Foundation, Greenlee and Associates, June 18, 1991: US05024944 (37 worldwide citation)

A method for somatic embryogenesis of soybean, (Glycine max), Glycine soja and other Glycine species is provided using immature cotyledon tissue, preferably with the embryonic axis removed, comprising culturing said tissue on a medium containing auxin, preferably NAA at a concentration of at least a ...


10
Knapp Charles F, Eades George S: Dynamic childbirth simulator for teaching maternity patient care. The University of Kentucky Research Foundation, Sherwood William E, July 9, 1974: US3822486 (34 worldwide citation)

A programmable patient simulator for teaching maternity patient care includes a life size manikin with a pelvis, vaginal canal, uterus, placenta, umbilical cord, and a fetal doll from which heart sounds are emitted. A programmable electro-pneumatic system controls the simulated uterine contractions, ...