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Larry K Keefer, Joseph A Hrabie: Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders. The United States of America represented by the Secretary of Health and Human Services, Leydig Voit & Mayer, April 11, 1995: US05405919 (131 worldwide citation)

A polymeric composition capable of releasing nitric oxide including a polymer and a nitric oxide-releasing N.sub.2 O.sub.2.sup.- functional group bound to the polymer; pharmaceutical compositions including the polymeric composition; and methods for treating biological disorders in which dosage with ...


2
Knazek Richard A, Gullino Pietro M, Dedrick Robert L, Kidwell William R: Cell culture on semi-permeable tubular membranes. The United States of America represented by the Secretary of Health, May 13, 1975: US3883393 (94 worldwide citation)

The growth of cells in vitro on semi-permeable, tube-shaped membranes or capillaries is disclosed. Cells are initially allowed to settle onto the outer surfaces of the membranes in a nutrient medium environment while the membranes are continuously perfused by oxygenated nutrient medium flowing throu ...


3
Lederman Robert J: Method and device for catheter-based repair of cardiac valves. The Government Of The United States Of America Represented By The Secretary Of Health And Human Services, Lederman Robert J, NOONAN William D, June 3, 2004: WO/2004/045378 (90 worldwide citation)

Disclosed is a system and method for catheter-based repair of cardiac valves, including transcatheter-mitral-valve-cerclage annuloplasty and transcatheter-mitral-valve reapposition. An exemplary embodiment of the system includes: a guiding cathether (100); one or more secondary catheters, such as a ...


4
P Demetrios Papahadjopoulos: Large unilamellar vesicles (LUV) and method of preparing same. The United States of America represented by the Secretary of Health Education and Welfare, John S Roberts Jr, Norman J Latker, Thomas G Ferris, March 7, 1978: US04078052 (82 worldwide citation)

A process and resulting product for producing large unilamellar phosphatidylserine vesicles (LUV) in the diameter of about 2,000-12,000 A which may additionally encapsulate a drug. The large vesicles are prepared from an initial phosphatidylserine aqueous solution which is subjected to ultrasound or ...


5
George M Thomas, John W Boretos, Donald C Syracuse, John A Clark, Anthony J Vita, Vincent A Gaudiani: Electrode for artificial pacemaker. The United States of America represented by the Secretary of Health Education and Welfare, John S Roberts Jr, Norman J Latker, Thomas G Ferris, September 12, 1978: US04112952 (64 worldwide citation)

An electrode for implantation in the heart to control atrio-ventricular block by artificial pacemaker including plural electrically conductive wires grouped in a bundle with spring metal arcuate prongs formed on one end thereof. A sheath is provided to compress the prongs for insertion of the electr ...


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Peter M Blumberg: Composition of resiniferatoxin and analogues thereof to cause sensory afferent C-Fiber and thermoregulatory desensitization. The United States of America represented by the Secretary of Health and Human Services, Birch Stewart Kolasch & Birch, March 1, 1994: US05290816 (56 worldwide citation)

The present invention relates to a method for desensitizing a subject animal, which comprises administering to the subject animal a therapeutically effective desensitizing amount of resiniferatoxin for desensitizing the subject animal to neurogenic inflammation, to chemically and thermally induced p ...


7
Theodor Kolobow, Yoichiro Ito: Blood cell separator. The United States of America represented by the Secretary of Health and Human Services, Vito J DiPietro, Thomas J Byrnes, Herbert Berl, November 2, 1982: US04356958 (49 worldwide citation)

A centrifugal blood component separator with a spiral helically inclined rotor chamber. The apparatus uses continuous blood flow-through without rotating seals. At the lower end of the helical rotor chamber there are terminals for blood input and packed red blood cell output, whereas at the higher e ...


8
Daniel L Alkon, Thomas P Vogl, Kim T Blackwell, Garth S Barbour: Dynamically stable associative learning neural network system. The United States of America represented by the Secretary of Health & Human Services, ERIM International, Spencer & Frank, October 13, 1998: US05822742 (40 worldwide citation)

A dynamically stable associative learning neural system includes a plurality of neural network architectural units. A neural network architectural unit has as input both condition stimuli and unconditioned stimulus, an output neuron for accepting the input, and patch elements interposed between each ...


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Otto A Gansow, Martin W Brechbiel: Backbone polysubstituted chelates for forming a metal chelate-protein conjugate. The United States of America represented by the Secretary of Health and Human Services, Morgan & Finnegan, September 21, 1993: US05246692 (36 worldwide citation)

New polysubstituted diethylenetriaminepentaacetic acid chelates and protein conjugates of the same are described together with the methods of preparing such compounds. A method of delivering radiolabelled compound of the present invention to a target site while minimizing the distribution of the com ...