1
Stephen A Boppart, Gary J Tearney, Brett E Bouma, Mark E Brezinski, James G Fujimoto, Eric A Swanson: Methods and apparatus for forward-directed optical scanning instruments. The General Hospital Corporation, Testa Hurwitz & Thibeault, November 26, 2002: US06485413 (663 worldwide citation)

An imaging system for performing forward scanning imaging for application to therapeutic and diagnostic devises used in medical procedures. The imaging system includes forward directed optical coherence tomography (OCT), and non-retroreflected forward scanning OCT. Also interferometric imaging and r ...


2
Nikiforos Kollias, Wei Dong Tian, Jenny E Freeman: Non-invasive tissue glucose level monitoring. The General Hospital Corporation, Kristofer E Elbing, January 7, 2003: US06505059 (484 worldwide citation)

Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.


3
Nikiforos Kollias, Wei Dong Tian, Jenny E Freeman: Non-invasive tissue glucose level monitoring. The General Hospital Corporation, Kristofer E Elbing, April 27, 2004: US06728560 (478 worldwide citation)

Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.


4
Ralph Weissleder, Alexei Bogdanov: Hydrogel compositions and methods of use. The General Hospital Corporation, Fish & Richardson, May 7, 1996: US05514379 (411 worldwide citation)

Biocompatible, biodegradable, hydrogels are prepared from a backbone bonded to a cross-linking agent. Suitable backbones include proteins and polysaccharides, e.g,, albumin, polymannuronic acid, or polygalacturonic acid. Suitable cross-linking agents include polyvalent derivatives of polyethylene or ...


5
James P Welch, Nathaniel M Sims: Network for portable patient monitoring devices. The General Hospital Corporation, Fish & Richardson, June 7, 1994: US05319363 (343 worldwide citation)

Multiple devices that are each suitable for use at a selected one of multiple locations are managed using a network of links that are each assigned to one of the locations. Each link is selectable between a state in which a device is not using the link and a state in which one or more devices are us ...


6
James F Gusella: Test for Huntingtons disease. The General Hospital Corporation, Saidman Sterne Kessler & Goldstein, May 19, 1987: US04666828 (283 worldwide citation)

A method for detecting the presence of the gene for Huntington's disease in a subject which comprises analyzing the human chromosome 4 of the subject for a DNA polymorphism, preferably a restriction fragment length polymorphism (RFLP), linked to Huntington's Disease.


7
Randall Y Grimes: Devices and methods for percutaneous mitral valve repair. The General Hospital Corporation, The Georgia Tech Research Corporation, Nutter McClennen & Fish, November 6, 2001: US06312447 (273 worldwide citation)

Devices and methods are provided for diagnosing and repairing mitral valve defects such as mitral valve regurgitation. According to an exemplary method, mitral valve function is visualized by transesophageal echocardiography. A catheter (


8
Nathaniel M Sims, John M Turner, Jane M Zeisloft, Daniel C Kusswurm, Ralph H LaBedz: Managing an inventory of devices. The General Hospital Corporation, Baxter International, Fish & Richardson, July 18, 1995: US05434775 (262 worldwide citation)

The locations of a plurality of devices are tracked using a network of communication links, each of which corresponds to a location. Each device is given a tag that identifies the device with respect to other devices and that is connectable to a communication link when the device is disposed at the ...


9
Gregory B Altshuler, R Rox Anderson, Dieter Manstein: Method and apparatus for the selective targeting of lipid-rich tissues. The General Hospital Corporation, Palomar Medical Technologies, Wolf Greenfield & Sacks P C, August 12, 2003: US06605080 (239 worldwide citation)

A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm ...


10
Guillermo J Tearney, Brett E Bouma: Optical methods for tissue analysis. The General Hospital Corporation, Dorsey & Whitney, June 12, 2007: US07231243 (215 worldwide citation)

The invention relates to methods and systems to optically analyze samples such as tissue based on speckle patterns of microscopic motion, such as Brownian motion.