1
Gifford Hanson S, Deem Mark E, Boyd Stephen: Aortic valve repair. The Foundry, Gifford Hanson S, Deem Mark E, Boyd Stephen, HESLIN James M, June 15, 2006: WO/2006/063199 (115 worldwide citation)

The present invention provides devices and methods for decalcifying an aortic valve. The methods and devices of the present invention break up or obliterate calcific deposits in and around the aortic valve through application or removal of heat energy from the calcific deposits.


2
Hanson Gifford, Mark E Deem, Stephen Boyd: Aortic valve repair. The Foundry, Townsend and Townsend and Crew, September 28, 2010: US07803168 (103 worldwide citation)

The present invention provides devices and methods for decalcifying an aortic valve. The methods and devices of the present invention break up or obliterate calcific deposits in and around the aortic valve through application or removal of heat energy from the calcific deposits.


3
Ronald G French, Sunmi K Chew, Hanson S Gifford III, Bernard H Andreas: Passive ventricular support devices and methods of using them. The Foundry, Townsend and Townsend and Crew, February 24, 2004: US06695769 (72 worldwide citation)

This is a surgical device and a method of using it. In particular, the device is one for supporting or constraining at least some part of the epicardial surface of the heart during a portion of the heartbeat, in particular during diastoly. This device may be used to assist in the treatment of conges ...


4
Hanson S Gifford III, Bernard H Andreas: Ventricular infarct assist device and methods for using it. The Foundry, Townsend and Townsend and Crew, February 3, 2004: US06685620 (64 worldwide citation)

This relates to surgical devices and methods of using them. In particular, the devices are used to support and to reform myocardial tissue in the region of and across an infarct. The devices provide tension across the infarct in varying degrees by attachment of the device to the myocardium at sites ...


5
Mark E Deem, Hanson Gifford: Systems and methods for delivery of a therapeutic agent. The Foundry, Townsend and Townsend and Crew, Jeffry Grainger Esq, October 27, 2009: US07608275 (47 worldwide citation)

Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum ...


6
Deem Mark, Gifford Hanson S Iii, Andreas Bernard, Chew Sunmi, French Ron, Sutton Doug: Methods and devices for treating aneurysms. The Foundry, THOMPSON Lynn M, January 15, 2004: WO/2004/004603 (47 worldwide citation)

Methods and devices provide delivery of one or more therapeutic agents to a treatment site at or near an aneurysm, such as an abdominal aortic aneurysm ('AAA'). Methods typically include placing a device at or near the AAA and releasing one or more therapeutic agents from the device. This may also i ...


7
Deem Mark E, Gifford Hanson S: Apparatus and methods for treating asthma using neurotoxin. The Foundry, Deem Mark E, Gifford Hanson S, HESLIN James, November 25, 2004: WO/2004/101028 (37 worldwide citation)

Apparatus providing intrabronchial delivery of neurotoxin to control the effects of asthma comprises a shaft having proximal and distal ends and a neurotoxin applicator assembly disposed on the distal end, wherein the neurotoxin applicator assembly comprises a deployable needle assembly, a rotating ...


8
Deem Mark, Gifford Iii Hanson S, Andreas Bernard, Chew Sunmi, French Ron, Sutton Doug: Methods and devices for luminal and sphincter augmentation. The Foundry, THOMPSON Lynn M, January 15, 2004: WO/2004/004544 (33 worldwide citation)

Devices (16, 20) and methods for augmenting or otherwise enhancing closure of body lumens include magnetic or magnetizable components or particles (16, 20) which are implanted in the wall of the lumen. The magnetic fields exerted by the components or particles (16, 18) act to close the body lumen wi ...


9
Mark E Deem, Hanson Gifford: Methods and systems for toxin delivery to the nasal cavity. The Foundry, Wilson Sonsini Goodrich & Rosati, January 31, 2012: US08105817 (30 worldwide citation)

Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light cha ...


10
Ronald G French, Sunmi K Chew, Hanson S Gifford III, Bernard H Andreas: Pericardium reinforcing devices and methods of using them. The Foundry, Townsend and Townsend and Crew, June 13, 2006: US07060023 (28 worldwide citation)

This is a surgical device and a method of using it. In particular, the device is one for reinforcing the pericardial sac surrounding the heart to assist in the treatment of congestive heart failure. The device, generically, is an enclosure having an interior and an exterior. The interior surface is ...