31
Steven N Popoff, Gary B Schneider: Treatment of osteopetrotic diseases. Temple University Of The Commonwealth System of Higher Education, Finch University of Health Sciences The Chicago Medical School, Nixon & Vanderhye P C, June 24, 1997: US05641747 (18 worldwide citation)

Bone resorption by osteoclast cells is promoted by activated vitamin D-binding factor, thereby providing an effective treatment for osteopetrosis. Conversely, inflammation-mediated bone loss is inhibited with antibody against the activated factor, providing a treatment for inflammation-mediated oste ...


32
Miller Larry S: Apparatus and method of endoscopic suturing. Temple University Of The Commonwealth System Of Higher Education, Miller Larry S, HANIFIN James Jr M, April 27, 2006: WO/2006/044837 (18 worldwide citation)

An adjustable suture assembly is provided that may be employed in various surgical procedures to draw and/or hold tissue and/or muscle together. The suture assembly may include a suture lock or tensioner that is adjustably securable to two or more lengths of suture to provide a surgeon with an abili ...


33
Andrei Z Budzynski, Linda C Knight, Ahmed A Hasan: Thrombus-targeted complexes of plasminogen activator and fibrin fragments. Temple University of the Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, February 22, 1994: US05288490 (17 worldwide citation)

Thrombolytic hybrids are formed as covalent or non-covalent complexes of fibrin fragments and plasminogen activator molecules. Native plasmin degradation fragments of fibrin or non-native fibrin fragments are covalently or non-covalently linked to plasminogen activators such as t-PA, scu-PA, urokina ...


34
Mark A Buese, Pao Sun Chang: Acid-catalyzed process for the production of cyclosiloxanes. Temple University of the Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, September 21, 1993: US05247116 (16 worldwide citation)

Cyclosiloxanes are produced by the acid-catalyzed redistribution of siloxane bonds in polysiloxane fluids at a temperature of about 20-200.degree. C. Little catalyst and no water or solvent is required. Cyclosiloxane product mixtures contain .ltoreq.1 wt. % cyclosiloxane species having more than 18 ...


35
Dulce C Veloso, Robert W Colman: Monoclonal antibodies to human plasma prekallikrein. Temple University of The Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, August 22, 1995: US05444156 (16 worldwide citation)

Four novel cell lines, ATCC #HB-8862 through ATCC #HB-8865 produce monoclonal antibody to human plasma prekallikrein. At least three of the antibodies also recognize plasma kallikrein, specifically the heavy chain thereof, and kallikrein-Cl-inhibitor complex; at least one of these three antibodies r ...


36
Alois H Nowotny: Process of enhancing immmunogenic response in mammals by the administration of synthetic glycolipid adjuvants. Temple University of the Commonwealth System of Higher Education, April 6, 1982: US04323561 (16 worldwide citation)

A process is described for enhancing the immunogenic response of mammals. N-acylated-D-glucosamines were administered parenterally in the form of liposomes to mice at or before the time of administration of an immunogen or radiation, with the result that comparable or superior enhancement of the imm ...


37
Hyunjo Kim, Reza Fassihi: Matrix for controlled delivery of highly soluble pharmaceutical agents. Temple University of the Commonwealth System of Higher Education, Ratner & Prestia, January 8, 2002: US06337091 (16 worldwide citation)

The present invention provides a new simple polymeric matrix tablet that delivers highly soluble drugs over long periods of time and is easy to manufacture. More specifically, the drug is first granulated with or encapsulated in a swellable polymer, such as a gum, to form a granule. This granule is ...


38
Leonard J Zubrzycki: Test method for the laboratory diagnosis of Gonorrhea and test strain of neisseria gonorrhoeae. Temple University of the Commonwealth System of Higher Education, Paul & Paul, May 1, 1984: US04446230 (16 worldwide citation)

A strain of Neisseria gonorrhoeae ATCC 31953 is described which is abnormal in that it has characteristically poor growth on chocolate agar at a temperature range of about 30.degree. C. to about 37.degree. C. in a CO.sub.2 atmosphere suitable for growth of N. gonorrhoeae. This strain is resistant to ...


39
E Premkumar Reddy, M V Ramana Reddy: Styryl sulfone anticancer agents. Temple University of the Commonwealth System of Higher Education, Drinker Biddle & Reath, March 19, 2002: US06359013 (16 worldwide citation)

Styryl sulfone compounds of the invention selectively inhibit proliferation of tumor cells, and induce apoptosis of such tumor cells, while sparing normal cells. The compounds, which are useful in the treatment of cancer, have the formula II:


40
Gwendolyn J Stewart, Marvin C Ziskin, Charles M Philips, Philip D Alburger, John W Lachman: Method of predicting the occurrence of deep vein thrombosis by non-invasive measurement of vessel diameter. Temple University of the Commonwealth System of Higher Education, Seidel Gonda Goldhammer & Abbott, January 26, 1988: US04721113 (15 worldwide citation)

A method of predicting the occurrence of deep vein thrombosis after a surgical procedure comprises monitoring changes in the internal diameter of a blood vessel using a non-invasive ultrasound technique. The frequency and magnitude of changes in vessel diameter are used to predict whether deep vein ...