1
Thomas H Shaffer, Marla R Wolfson, Thomas F Miller, Raymond Foust III: Breathable liquid elimination analysis. Temple University Of The Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco P C, January 7, 1997: US05590651 (252 worldwide citation)

The amount of breathable liquid eliminated from a mammal through volatilization in the lungs and/or through skin transpiration is detected by measuring the amount of saturation of the expiratory gas by vapors or the breathable liquid. Instantaneous saturation values are employed to gauge the amount ...


2
Robert J Suhadolnik, Wolfgang Pfleiderer: Dual action 2,5-oligoadenylate antiviral derivatives and uses thereof. Temple University Of The Commonwealth System Of Higher Education, Seidel Gonda Lavorgna & Monaco P C, August 27, 1996: US05550111 (218 worldwide citation)

Viral infection is inhibited in mammals by administration of metabolically stable, non-toxic 2', 5'-oligoadenylate (2-5A) derivatives that have a dual therapeutic effect. The compounds activate the intracellular latent 2-5A dependent endoribonuclease RNase L and also inhibit the action of viral DNA ...


3
Robert J Suhadolnik, Wolfgang Pfleiderer: Encapsulated 2,5-phosphorothioate oligoadenylates. Temple University of the Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, February 23, 1993: US05188897 (209 worldwide citation)

Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages is


4
Robert J Suhadolnik, Wolfgang Pfleiderer: 2,5-phosphorothioate oligoadenylates and their covalent conjugates with polylysine. Temple University of the Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, April 11, 1995: US05405939 (205 worldwide citation)

Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages is of the Sp configuration possess increased antiviral activity and/or metabolic stabil ...


5
Robert G Stern, Thomas H Shaffer, Marla R Wolfson: Fluorochemical liquid augmented cryosurgery. Temple University of the Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco PC, April 21, 1998: US05741248 (192 worldwide citation)

A method for cryogenic treatment of a lesion which includes the steps of delivering a fluorochemical liquid to the lesion, placing at least one cryoprobe into the lesion, and circulating cryogenic fluid through the cryoprobe, the cryogenic fluid causing an ice ball to form in a vicinity around the c ...


6
K Michael Sekins, Thomas H Shaffer, Marla R Wolfson: Lung cancer hyperthermia via ultrasound and/or convection with perfiuorochemical liquids. Biopulmonics, Temple University Of the Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, October 27, 1992: US05158536 (154 worldwide citation)

A hyperthermic treatment of lung cancer, by temporarily filling with a liquid medium preselected pulmonary air passages adjoining pulmonary tissues containing malignant cells, circulating exogenously heated liquid medium at from about 41.degree. to ab


7
Alan M Gewirtz, Bruno Calabretta: Antisence oligonucleotides to c-myb proto-oncogene and uses thereof. Temple University of the Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, March 24, 1992: US05098890 (116 worldwide citation)

Oligonucleotides are provided having a nucleotide sequence complementary to at least a portion of the mRNA transcript of the human c-myb gene. These "antisense" oligonucleotides are hybridizable to the c-myb mRNA transcript. Such oligonucleotides are useful in treating hematologic neoplasms and in i ...


8
Yuan Shi: System for automatically generating efficient application - customized client/server operating environment for heterogeneous network computers and operating systems. Temple University of the Commonwealth System of Higher Education, David Newman & Associates, January 10, 1995: US05381534 (114 worldwide citation)

A high level virtual computer in a heterogeneous hardware and software environment. A user specifies the hardware and software configuration of a virtual computer employing multiple coarse grain single instruction, multiple data (SIMD); multiple instruction, multiple data (MIMD); and pipelined paral ...


9
Robert F Buckman Jr, Michael M Badellino: Inflatable and expandable direct manual cardiac compression device. Temple University Of The Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco P C, November 5, 1996: US05571074 (104 worldwide citation)

A heart massager for substernal heart massage is disclosed. The heart massager utilizes a heart-contacting member adapted for insertion into a thoracic cavity for directly contacting the heart and a handle attached thereto for manually manipulating the apparatus. The heart-contacting member includes ...


10
Thomas H Shaffer, Marla R Wolfson: Process control and apparatus for ventilation procedures with helium and oxygen mixtures. Temple University Of The Commonwealth System of Higher Education, Seidel Gonda Lavorgna & Monaco, July 4, 1995: US05429123 (89 worldwide citation)

A process is provided for controlling a ventilation procedure wherein a heliox ventilation system passes a breathing medium through at least a portion of a patient's pulmonary pathways. In this process, desired ranges for certain process parameters associated with the heliox ventilation system are e ...



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