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Samejima Masayoshi, Hirata Goichi, Koida Yoshiyuki, Kobayashi Yoshinori, Kida Akira: Enteric microcapsules and process for the preparation thereof.. Tanabe Seiyaku Co, May 4, 1983: EP0077956-A1 (49 worldwide citation)

Novel enteric microcapsules containing an active compound as a core material, the coating walls of which consist essentially of ethylcellulose and an enteric polymer material, and optionally a water-swellable polymer material being incorporated into the core material, and a process for the preparati ...


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Tsujihara Kenji, Kawaguchi Takayuki, Okuno Satoshi, Yano Toshiro: Camptothecin derivatives. Tanabe Seiyaku Co, February 5, 1997: EP0757049-A1 (37 worldwide citation)

A camptothecin derivative comprising a compound of the formula ÄIÜ: wherein R is a substituted or unsubstituted lower alkyl group, X is a group of the formula: -NHR (R is a hydrogen atom or a lower alkyl group) or a group of -OH, and Alk is a straight chain or branched chain alkylene group having op ...


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Yamagata Koichi, Umemura Isao, Shibatani Takeji: Assay for detecting nucleic acid sequence.. Tanabe Seiyaku Co, Eiken Chemical, February 22, 1995: EP0639647-A2 (36 worldwide citation)

Assay for detecting nucleic acid sequence, which comprises the steps: [A] contacting (1) a target single-stranded nucleic acid, (2) a pair of nucleic acid primers having nucleotide sequence complementary to the target nucleic acid and its complementary chain respectively, (3) a fluorescent-labeled n ...


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Noda Kazuo, Osawa Takashi, Kobayashi Masao, Ishikawa Shigeyuki: Controlled release pharmaceutical preparation.. Tanabe Seiyaku Co, January 2, 1992: EP0463877-A1 (33 worldwide citation)

A controlled release pharmaceutical preparation comprising a core containing a medicinal compound and a coating layer containing a water-repellent salt and a water-insoluble and slightly water-permeable acrylic polymer having trimethylammoniumethyl group. Said preparation releases a medicinal compou ...


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Yamada Koichiro, Yasuda Kosuke, Kikkawa Kohei, Kohno Rikako Touwacity Co Op: Benzenesulfonamide derivative and process for preparing thereof.. Tanabe Seiyaku Co, June 21, 1995: EP0658548-A1 (31 worldwide citation)

A benzenesulfonamide derivative of the formula [I]: wherein Ring A and Ring B are the same or different and each substituted or unsubstituted benzene ring, Q is a single bond or a group of the formula: -O-, -S-, -SO-, -SO2- or -CH2-, Y is a group of the formula: -O-, -S- or -NH-, Alk is lower alkyle ...


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Ukita Tatsuzo, Ikezawa Katsuo, Yamagata Shinsuke: Naphthalene derivatives, process for the preparation thereof, and intermediates therefor, and pharmaceutical compositions comprising them. Tanabe Seiyaku Co, December 18, 1996: EP0748805-A1 (31 worldwide citation)

Naphthalene derivatives of the formula ÄIÜ: wherein R and R are the same or different and are each H, protected or unprotected OH, one of R and R is protected or unprotected hydroxymethyl, and the other is H, lower alkyl, or protected or unprotected hydroxymethyl, R and R are the same or different a ...


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Noda Kazuo, Hirakawa Yoshiyuki, Yoshino Hiroyuki, Kubo Nee Nagata Minako: Pharmaceutical preparation for controlled release of a medicinal compound at a targeted site in the intestinal tract.. Tanabe Seiyaku Co, December 21, 1994: EP0629398-A1 (28 worldwide citation)

A pharmaceutical preparation controlled to release a medicinal compound at a targeted site in the intestinal tract comprises a medicinal compound-containing phase and an enteric coating phase provided around the medicinal compound-containing phase, said medicinal compound-containing phase releasing ...