1
Okuno Yoshinobu, Isegawa Yuiji, Sasao Fuyoko, Ueda Shigeharu: Immunogenic human influenza a virus haemagglutinin polypeptides.. Takara Shuzo Co, October 26, 1994: EP0621339-A2 (38 worldwide citation)

An anti-human influenza virus antibody which recognizes the stem regions of haemagglutinin molecules of the H1N1 and H2N2 subtypes and has a neutralization activity but does not recognize the stem region of the H3N2 subtype and has no neutralization activity. An immunogenic artificial polypeptide ha ...


2
Yoshinobu Okuno, Atsushi Oshima, Hirofumi Yoshioka, Takashi Takabatake, Ikunoshin Kato: A dna which codes for the variable region of the anti-human influenza a type virus antibody recognizing the h,n, and h2n2 subtypes of haemagglutinin.. Takara Shuzo Co, October 4, 1995: EP0675199-A2 (37 worldwide citation)

A DNA coding for the variable region of the anti-human influenza A type virus antibody having the following characteristics (a) and (b); (a) recognizing the stem region of haemaggulutinin molecule of the H1N1 and H2N2 subtypes of human influenza A type virus but not recognizing the stem region of ha ...


3
Shimada Masamitsu, Kato Ikunoshin, Fukushima Michio, Fujinaga Kei: Method for the detection of human papilloma-virus.. Takara Shuzo Co, December 12, 1990: EP0402132-A2 (34 worldwide citation)

A method for the detection of human papilloma-virus HPV 16, HPV 18, HPV 33 or any combination of these viruses is disclosed. The method employs amplification by use of a pair of oligonucleotide primers of at least one DNA region chosen from the group of DNA regions of the structures shown in Formula ...


4
Mukai Hiroyuki, Yamamoto Junko, Takeda Osamu, Miyake Kazue, Uemori Takashi, Sato Yoshimi, Moriyama Mariko, Sawaragi Haruhisa, Hagiya Michio, Asada Kiyozo, Kato Ikunoshin: Method for amplifying a nucleic acid sequence employing a chimeric primer. Takara Shuzo Co, January 2, 2002: EP1167524-A1 (25 worldwide citation)

A convenient and effective method for amplifying a nucleic acid sequence characterized by effecting a DNA synthesis reaction in the presence of chimeric oligonucleotide primers; a method for supplying a large amount of DNA amplification fragments; an effective method for amplifying a nucleic acid se ...


5
Miki Kojiro, Mori Takeshi, Ohkawa Hiromi, Hosokawa Yumi, Kondo Akihiro, Kato Ikunoshin: Pretreatment apparatus for use in analysis.. Horiba, Takara Shuzo Co, September 1, 1993: EP0557828-A1 (25 worldwide citation)

The apparatus for the pretreatment of substances to be analyzed is capable of full-automatically conducting various kinds of operation, e.g. in particular the mounting and removal of caps (11) on and from the mouth portions of sample vials (10) the replacement of tips (19) in a tip holder (15), the ...


6
Taguchi Yuki, Nishikawa Mio, Koyama Nobuto, Yamamoto Katsuhiko, Asada Kiyozo, Kato Ikunoshin: Dna encoding a hyperthermostable alpha-amylase.. Takara Shuzo Co, April 19, 1995: EP0648843-A1 (24 worldwide citation)

[Object] To provide a genetic engineering process for producing alpha -amylase with the use of an isolated hyperthermostable alpha -amylase gene. [Constitution] A hyperthermostable alpha -amylase gene comprising a nucleotide sequence represented by SEQ ID NO: 1 of the sequence listing (obtained from ...


7
Shimada Atsushi, Koyama Nobuto, Asada Kiyozo, Odate Miki, Hashino Kimikazu, Kato Ikunoshin: Hyperthermostable beta-galactosidase gene. Takara Shuzo Co, December 20, 1995: EP0687732-A1 (19 worldwide citation)

An isolated SDS-resistant hyperthermostable beta -galactosidase gene derived from Pyrococcus furiosus of sequence SEQ ID NO: 2 and genes hybridizable with it. A method of cloning the hyperthermostable beta -galactosidase gene in which one of the above genes or parts thereof is used as a probe or pri ...


8
Asada Kiyozo, Uemori Takashi, Ueno Takashi, Koyama Nobuto, Hashino Kimikazu, Kato Ikunoshiu: Method for gene introduction into target cells by retrovirus. Takara Shuzo Co, October 14, 1998: EP0870839-A1 (16 worldwide citation)

A method for increasing the efficiency of gene transfer into target cells with a retrovirus is disclosed. In the method, the target cells are infected with the retrovirus in the presence of either a mixture of an effective amount of a functional material having retrovirus binding domain and an effec ...


9
Uemori Takashi, Ishino Yoshizumi, Kato Ikunoshin: Dna polymerase from pyrococcus furiosus. Takara Shuzo Co, October 14, 1998: EP0870832-A1 (15 worldwide citation)

The present invention relates to a DNA polymerase possesses the properties of 1) exhibiting higher polymerase activity when assayed by using as a substrate a complex resulting from primer annealing to a single stranded template DNA, as compared to the case where an activated DNA is used as a substra ...


10
Takesako Kazutoh, Shimanaka Kazuo, Yamamoto Junko, Haruna Fumiyo, Nakamura Teruya, Yamaguchi Hideyo, Uchida Katsuhisa, Ikai Katsushige: Novel antibiotics r106.. Takara Shuzo Co, January 24, 1990: EP0352092-A2 (15 worldwide citation)

Antibiotic compounds R106 of formula (I): are antifungal agents. They may be produced by culture of microorganisms of the genus Aureobasidium, e.g. of new species Aureobasidium pullulans No.R106 exemplified by the type strain deposited under accession No.FERM BP-1938.