1
Lax Ronald G, Herd Allen K: Inhalation device. Syntex Corporation, Merker Evelyn K, Hirsch Joseph I, March 5, 1974: US3795244 (49 worldwide citation)

An inhalation device having means to engage the free end of a powdered medicament-holding capsule as the capsule is pierced to provide outlet ports for the powdered medicament held therein. Such engagement ensures that the capsule is completely seated in the rotary member on which it is supported an ...


2
Booher Keith E, Van Loozen George M: Implanter having an improved cartridge ejector. Syntex Corporation, July 10, 1973: US3744493 (47 worldwide citation)

A pellet implanter includes a tubular body having a movable plunger therein extending from the rear end thereof through a hollow needle at the forward end thereof for pushing pellets from a pellet cartridge through the cartridge and through the hollow needle into the animal being treated. A side bre ...


3
Brian H Vickery: Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals. Syntex Corporation, Tom M Moran, November 16, 1976: US03991750 (36 worldwide citation)

Dromostanolone propionate has been found to result in a surprisingly large increase in weight in animals when administered as a pellet implant. In female animals, e.g. heifers, estrus is also suppressed. A particularly effective implant pellet exhibits a substantially constant rate of drug delivery ...


4
Martin Katz, John S Kent: Inert core implant pellet. Syntex Corporation, Tom M Moran, Joseph I Hirsch, December 25, 1979: US04180560 (35 worldwide citation)

A novel spherical implant pellet containing estradiol, estradiol benzoate, or mixtures thereof as the sole active ingredients which exhibits a substantially constant drug release rate over a timer period and substantially abrupt termination of drug release at the end of the time period is prepared w ...


5
Fried John H, Harrison Ian T: 2-(6-Methoxy-2-naphthyl)acetic acid. Syntex Corporation, Hirsch Joseph I, Walker William B, September 9, 1975: US3904682 (34 worldwide citation)

2-(6'-Substituted-2'-naphthyl)acetic acid derivatives substituted at the 2-position of the acetic acid moiety with methyl, methylene or halomethylene and the salts and esters thereof have anti-inflammatory, analgesic and anti-pyretic activities.


6
Eugene J Segre: Dispensing packages containing novel cyclic progestogen-interrupted estrogen oral contraceptive regimens. Syntex Corporation, Joseph I Hirsch, William B Walker, March 9, 1976: US03942641 (32 worldwide citation)

This invention relates to a method of fertility control by use of novel cyclic progestogen-interrupted estrogen oral contraceptive regimens. Considering the first day of menstrual flow as day one of a 28 day medication administration cycle, a combined formulation of estrogen and progestogen substanc ...


7
Subramaniam Shastri, Zafaruzzaman I Shaikh: Propylene carbonate ointment vehicle. Syntex Corporation, Tom M Moran, Joseph I Hirsch, April 12, 1977: US04017615 (28 worldwide citation)

An ointment vehicle containing from 0.5 to 30 percent propylene carbonate, from 30 to 99.5 weight percent petrolatum and/or polysiloxane, compatible cosolvent, the concentration of which in combination with propylene carbonate is from 0.5 to 70 percent, and, optionally, surfactants, thickeners, pres ...


8
John H Fried, Ian T Harrison: Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof. Syntex Corporation, Joseph I Hirsch, William B Walker, December 21, 1976: US03998966 (25 worldwide citation)

2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positi ...


9
Martin Katz, John S Kent: Inert core implant pellet. Syntex Corporation, Tom M Moran, William B Walker, June 20, 1978: US04096239 (24 worldwide citation)

A novel spherical implant pellet containing estradiol, estradiol benzoate, or mixtures thereof as the sole active ingredients which exhibits a substantially constant drug release rate over a timer period and substantially abrupt termination of drug release at the end of the time period is prepared w ...


10
Ernst Felder, Davide Pitre, Hans Zutter: Process for the resolution of (+)- and (-)-6-methoxy-.alpha.-methyl-2-naphthaleneacetic acid. Syntex Corporation, Joseph I Hirsch, John A Dhuey, January 20, 1981: US04246164 (22 worldwide citation)

The subject of the invention is a process for resolving mixtures of (+)- and (-)-6-methoxy-.alpha.-methyl-2-naphthaleneacetic acid into the enantiomers thereof, characterized in that N-methyl-D-glucamine [=1-deoxy-1-(methylamino)-D-glucitol] is used as the resolving agent, so that the 6-methoxy-.alp ...