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Gross Peter, Jörnvall Hans, Thiry Michel, Formicka Zeppezauer Crazyna, Zeppezauer Michael: Bis-met histones. Symbiotec Gesellschaft Zur Forschung Und Entwicklung Auf Dem Gebiet Der Biotechnologie Mbh, Gross Peter, Jörnvall Hans, Thiry Michel, Formicka Zeppezauer Crazyna, Zeppezauer Michael, VOSSIUS Siebertstrasse 4 81675 Munich, October 16, 2008: WO/2008/122434

The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing s ...


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Zeppezauer Michael, Reiner Class: (De) Verwendung von histonen zu therapeutischen zwecken, (En) Use of histones for therapeutic purposes. Symbiotec Gesellschaft Für Forschung Und Entwicklung Auf Dem Gebiet Der Biotechnologie Mbh, Zeppezauer Michael, Reiner Class, PÄTZOLD Herbert, November 16, 2006: WO/2006/119912

(EN) The invention relates to the use of at least one human recombinant histone, especially at least one histone H1 subtype, and/or a therapeutic histone fraction as a basis for the treatment of thrombocytopenia.(DE) Die Erfindung betrifft die Verwendung wenigstens eines humanen rekombinanten Histon ...


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Class Reiner, Zeppezauer Michael: Antimicrobial histone h1 compositions, kits, and methods of use thereof. Symbiotec, Philadelphia Health &Amp, Educatio, May 2, 2002: EP1200463-A2

The invention includes antibiotic pharmaceutical compositions comprising eukaryotic histone H1 protein and methods of using eukaryotic histone H1 protein to kill or to inhibit the growth of microorganisms, including, but not limited to, human pathogenic bacteria. The invention further includes a euk ...


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Zeppezauer Michael, Leinenbach Hans Peter, Class Reiner, Fassbender Cordula: Use of histons for the production of medicaments. Symbiotec, January 26, 2000: EP0973541-A1

A therapeutic or prophylactic agent for cancer is disclosed which damages the membrane and kills cancer cells, in particular of the blood-forming system, having membrane protein aggregates which contain several core histones or largely core-like histones and/or their parts. The therapeutic or prophy ...


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Thiry Michel, Gross Peter, Joernvall Hans, Formicka Zeppezauer Crazyna, Zeppezauer Michael: Bis-met histones. Symbiotec Thiry Michel, Ding Xianglan, Pang Dongcheng, March 24, 2010: CN200880014894

The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing s ...


37
Class Reiner: Use of histones for the early diagnosis and/or preventative therapy of virally-infected living cells and a biochip for carrying out said diagnosis. Symbiotec Ges Zur Erforschung, geqiang qinkai zong, October 31, 2007: CN200580022753

The invention relates to a biologically-active agent, in particular, for the early diagnosis and/or preventative therapy of virally-infected living cells, the efficacy of which is selective for the cell membranes of the virally-infected cells, which are modified in a characteristic manner after vira ...


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Zeppezauer Michael, Schoenberger Arno Dr, Cebecauer Ladislav Dr: Peptide for production of diagnostic and therapeutic agent of systemic erythematodes. Symbiotec G Zur Forsch &Amp Entwickl Auf Dem Gebiet Der Biotechnol Mbh, October 19, 1993: JP1993-271281

PURPOSE: To provide a peptide capable of executing the diagnosis of a systemic erythematodes (SLE) with a high degree of exactness and producing a therapeutic agent for SLE. CONSTITUTION: This peptide has an antigen or immunogen determinant by an autoantibody in the body fluid of a systemic erythema ...


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Zeppezauer Michael, Schoenberger Arno, Cebecauer Ladislav: Peptide for producing preparation for diagnosis and therapy of systemic lupus erythematosus. Symbiotec Ges Zur Forschung &Amp Entwicklung Au F Dem Gebiet Der Biotechnologie Mbh, January 12, 2006: JP2006-008694

PROBLEM TO BE SOLVED: To provide a peptide having an immunogenic determinant by an autoantibody of a patient suffering from SLE (systemic lupus erythematosus).SOLUTION: A monoclonal antibody and anti-idiotypic antibody specific in the very same manner as an antibody of the patient suffering from the ...


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Zeppezauer Michael, Class Reiner: Use of histones for therapeutic purposes. Symbiotec Gesellschaft Fur Forschung Und Entwicklung Auf Dem Gebiet Der Biotechnologie Mbh, January 18, 2008: KR1020077025805

The invention relates to the use of at least one human recombinant histone, especially at least one histone H1 subtype, and/or a therapeutic histone fraction as a basis for the treatment of thrombocytopenia.