1
David L Clapper, Melvin J Swanson, Sheau Ping Hu, Richard A Amos, Terrence P Everson: Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups. SurModics, Fredrikson & Byron P A, September 19, 2000: US06121027 (438 worldwide citation)

A polybifunctional reagent is provided having a polymeric backbone, one or more pendent photoreactive moieties, and two or more pendent bioactive groups. The reagent can be activated to form a bulk material or can be brought into contact with the surface of a previously formed biomaterial and activa ...


2
Stephen J Chudzik, Aron B Anderson, Ralph A Chappa, Timothy M Kloke: Bioactive agent release coating. Surmodics, Fredrikson & Byron P A, April 10, 2001: US06214901 (290 worldwide citation)

A coating composition for use in coating implantable medical devices to improve their ability to release bioactive agents in vivo. The coating composition is particularly adapted for use with devices that undergo significant flexion and/or expansion in the course of their delivery and/or use, such a ...


3
Stephen J Chudzik, Aron B Anderson, Ralph A Chappa, Timothy M Kloke: Bioactive agent release coating. Surmodics, Fredrikson & Byron P A, February 5, 2002: US06344035 (265 worldwide citation)

A coating composition for use in coating implantable medical devices to improve their ability to release bioactive agents in vivo. The coating composition is particularly adapted for use with devices that undergo significant flexion and/or expansion in the course of their delivery and/or use, such a ...


4
Patrick E Guire, Kristin S Taton, John V Wall: Particle immobilized coatings and uses thereof. Surmodics, Kagan Binder PLLC, March 25, 2014: US08679454 (163 worldwide citation)

Surface coatings including microparticles immobilized in a matrix of polymeric material on a substrate are described. The microparticles can also include an agent which can be useful for various applications, such as medical applications. This invention relates to the field of surface coatings for u ...


5
Ralph A Chappa, Sheau Ping Hu, Dale G Swan, Melvin J Swanson, Patrick E Guire: Target molecule attachment to surfaces. Surmodics, Merchant & Gould P C, October 15, 2002: US06465178 (143 worldwide citation)

Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in at ...


6
Patrick E Guire, Kristin S Taton: Self assembling monolayer compositions. SurModics, Fredrikson & Byron P A, February 10, 2004: US06689473 (107 worldwide citation)

A surface coating composition for providing a self-assembling monolayer, in stable form, on a material surface or at a suitable interface, as well as a method of preparing such a composition and a method of using such a composition to coat a surface, such as the surface of an implantable medical dev ...


7
Stephen J Chudzik, Aron B Anderson, Ralph A Chappa, Timothy M Kloke: Bioactive agent release coating. SurModics, Fredrikson & Byron P A, March 7, 2006: US07008667 (102 worldwide citation)

A coating composition for use in coating implantable medical devices to improve their ability to release bioactive agents in vivo. The coating composition is particularly adapted for use with devices that undergo significant flexion and/or expansion in the course of their delivery and/or use, such a ...


8
Lise W Duran, Melvin J Swanson, Richard A Amos, Sheau Ping J Hu, Patrick E Guire: Reagent and method for attaching target molecules to a surface. SurModics, Fredrikson & Byron P A, January 12, 1999: US05858653 (101 worldwide citation)

Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of attracting the target molecule as well as groups capable of covalently binding to the target molecule, once attracted ...


9
Stephen J Chudzik, Aron B Anderson, Ralph A Chappa, Timothy M Kloke: Bioactive agent release coating. SurModics, Fredrikson & Byron P A, May 10, 2005: US06890583 (98 worldwide citation)

A coating composition for use in coating implantable medical devices to improve their ability to release bioactive agents in vivo. The coating composition is particularly adapted for use with devices that undergo significant flexion and/or expansion in the course of their delivery and/or use, such a ...


10
Stephen J Chudzik, David L Clapper: Crosslinkable macromers. Surmodics, Frederickson & Byron P A, June 25, 2002: US06410044 (97 worldwide citation)

A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The macromer system includes two or more polymer ...