1
Conte Immacolata, Ercolani Caterina, Narjes Frank, Pompei Marco, Rowley Michael, Stansfield Ian: Tetracyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Conte Immacolata, Ercolani Caterina, Narjes Frank, Pompei Marco, Rowley Michael, Stansfield Ian, MAN Jocelyn, May 4, 2006: WO/2006/046030 (59 worldwide citation)

The present invention relates to tetracyclic indole compounds of formula (I); wherein R1, R2, A, Ar, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C ...


2
Narjes Frank, Stansfield Ian: Tetracyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Narjes Frank, Stansfield Ian, MAN Jocelyn, March 15, 2007: WO/2007/029029 (55 worldwide citation)

The present invention relates to tetracyclic indole derivatives of formula (I): wherein Ar, A, R1, R2, L, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepati ...


3
Ercolani Caterina, Habermann Joerg, Narjes Frank, Ponzi Simona, Rowley Michael, Stansfield Ian: Tetracyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Ercolani Caterina, Habermann Joerg, Narjes Frank, Ponzi Simona, Rowley Michael, Stansfield Ian, MAN Jocelyn, May 4, 2006: WO/2006/046039 (42 worldwide citation)

The present invention relates to tetracyclic indole compounds of formula (I); wherein R1, R2, R14, R15, A, Ar, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatit ...


4
Avolio Salvatore, Di, Filippo Marcello, Harper Steven, Narjes Frank, Pacini Barbara, Pompei Marco, Rowley Michael, Stansfield Ian: Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Avolio Salvatore, Di, Filippo Marcello, Harper Steven, Narjes Frank, Pacini Barbara, Pompei Marco, Rowley Michael, Stansfield Ian, MAN Jocelyn, October 14, 2004: WO/2004/087714 (36 worldwide citation)

The present invention relates to indole and azaindole compounds of formula (I): wherein X1, X2, X3, X4, A1, Ar1, R1, R2 and n are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.


5
Capito Elena, Habermann Joerg, Narjes Frank, Rico, Ferreira Maria Del Rosario, Stansfield Ian: Pentacyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Capito Elena, Habermann Joerg, Narjes Frank, Rico, Ferreira Maria Del Rosario, Stansfield Ian, MAN Jocelyn, November 15, 2007: WO/2007/129119 (24 worldwide citation)

The present invention relates to pentacyclic indole derivatives of formula (I): wherein A, Ar, R1, R2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis ...


6
Conte Immacolata, Martin, Hernando Jose Ignacio, Malancona Savina, Ontoria, Ontoria Jesus Maria, Stansfield Ian: Imidazole and thiazole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Conte Immacolata, Martin, Hernando Jose Ignacio, Malancona Savina, Ontoria, Ontoria Jesus Maria, Stansfield Ian, MAN Jocelyn, January 26, 2006: WO/2006/008556 (21 worldwide citation)

The present invention relates to compounds of the formula (I), wherein R1, R2, A, B, D, E, F, G and Ar are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.


7
Koch Uwe, Mackay Angela Claire, Narjes Frank, Stansfield Ian: Benzofuran- carboxamide derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Koch Uwe, Mackay Angela Claire, Narjes Frank, Stansfield Ian, HUSSAIN Deeba, October 23, 2008: WO/2008/125874 (20 worldwide citation)

A compound of the formula (I): as defined herein, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing a compound of the formula (I) for use in inhibiting hepatitis C virus polymerase and/or of treating or preventing an illness due to hepatitis C virus,


8
Conte Immacolata, Ercolani Caterina, Guiliano Claudio, Migliaccio Giovanni, Stansfield Ian: Modulators of hcv replication. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Conte Immacolata, Ercolani Caterina, Guiliano Claudio, Migliaccio Giovanni, Stansfield Ian, MAN Jocelyn, April 13, 2006: WO/2006/038039 (10 worldwide citation)

The present invention is directed to the use of compounds of formula (I): 1 R X 3 R Y ( I) 2 R 5 where X, Y, R1, R2 and R3 are defined therein, which can act as modulators of viral replication and/or virus production, especially of the hepatitis C virus (HCV), in a cell based system.


9
Stansfield Ian, Koch Uwe, Habermann Joerg, Narjes Frank: Antiviral indoles. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Stansfield Ian, Koch Uwe, Habermann Joerg, Narjes Frank, ROLLINS Anthony J, June 26, 2008: WO/2008/075103 (4 worldwide citation)

Compounds of the formula (I) wherein A, B, D, M, Ar, W, X, Y, Z and R1 are as defined herein, are useful in the prevention and treatment of hepatitis C infections. The compounds, their preparation, pharmaceutical compositions containing them and their use in medicine are disclosed.


10
Di, Filippo Marcello, Harper Steven, Narjes Frank, Pacini Barbara, Petrocchi Alessia, Rowley Michael, Stansfield Ian: Tetracyclic indole derivatives as antiviral agents. Istituto Di Ricerche Di Biologia Molecolare P Angeletti, Di, Filippo Marcello, Harper Steven, Narjes Frank, Pacini Barbara, Petrocchi Alessia, Rowley Michael, Stansfield Ian, MAN Jocelyn, May 18, 2007: WO/2007/054741 (3 worldwide citation)

The present invention relates to tetracyclic indole derivatives of formula (I); wherein Ar, D1, D2, D3, D4, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepa ...