1
Richard C Gunderson, James S Sharrow, Jeffrey A McBroom: Method of diagnosing tissue with guidewire. SpectraScience, August 8, 1995: US05439000 (388 worldwide citation)

The present invention provides a guidewire which incorporates an optical fiber and associated diagnostic apparatus for diagnosing tissue in vivo. Use of the present invention provides for diagnosis of tissue and tailoring of the therapeutic portion of the procedure to the tissue or condition identif ...


2
Richard C Gunderson, James S Sharrow, Jeffrey A McBroom: System for diagnosing tissue with guidewire. SpectraScience, Schwegman Lundberg Woessner & Kluth P A, February 11, 1997: US05601087 (309 worldwide citation)

The present invention provides a guidewire which incorporates an optical fiber and associated diagnostic apparatus for diagnosing tissue in vivo. Use of the present invention provides for diagnosis of tissue and tailoring of the therapeutic portion of the procedure to the tissue or condition identif ...


3
Michael L Auer, Victor I Chornenky, Peter T Fettig, Richard C Gunderson, Jeffrey A McBroom, James S Sharrow: Guidewire catheter and apparatus for diagnostic imaging. SpectraScience, Schwegman Lundberg & Woessner, January 24, 1995: US05383467 (277 worldwide citation)

A catheter comprising a unitary guidewire and single mode optical fiber is used to illuminate human body channels, such as a tissue mass within a blood vessel, for purposes of diagnosis. A low coherent light source illuminates the tissue and provides a reference beam. Illumination that is reflected ...


4
Brain T McMahon, Chester E Sievert Jr, Scott R Wilson, Ronald R Zimmermann, Robert A Palme, John G Yager, David R Walsh: Optical biopsy system and methods for tissue diagnosis. SpectraScience, Schwegman Lundberg Woessner & Kluth P A, January 16, 2001: US06174291 (251 worldwide citation)

A system characterizes tissue using fluorescence spectroscopy, such as light-induced fluorescence. Native fluorescence (“autofluorescence”) from endogenous tissue without requiring fluorescence-enhancing agents is used to distinguish between normal tissue, hyperplastic tissue, adenomatous tissue, an ...


5
Chester E Sievert Jr, Scott R Wilson, Greg L Townsend, James L Pokorney, Brian T McMahon: Optical forceps system and method of diagnosing and treating tissue. SpectraScience, Schwegman Lundberg Woessner & Kluth P A, May 28, 2002: US06394964 (140 worldwide citation)

A biopsy forceps device is provided for obtaining tissue samples, or removing tissue for therapeutic reasons, at a site within a body, while maintaining access to the site through an access lumen of the biopsy forceps. The device includes an elongate tubular body for introduction into the body and n ...


6
Gregg S Sutton, Brian T McMahon: Optical biopsy forceps. SpectraScience, Schwegman Lundberg Woessner & Kluth P A, October 10, 2000: US06129683 (74 worldwide citation)

An integrated optical biopsy forceps device and a method for tissue identification by optical analysis and biopsy sampling at a site within the body. The device includes an elongated catheter body for introduction into the body and navigation to an area of interest. An optical fiber extends through ...


7
Greg L Townsend, Brian T McMahon, Chester E Sievert Jr, Scott R Wilson, James L Pokorney, John P Farris, David E Porter, Mark H Feddern: Optical biopsy forceps system and method of diagnosing tissue. SpectraScience, Schwegman Lundberg Woessner & Kluth P A, May 23, 2000: US06066102 (71 worldwide citation)

A biopsy forceps device is provided for obtaining tissue samples at a site within the body, while maintaining access to the site through an access lumen of the biopsy forceps. The device includes an elongate tubular body for introduction into the body and navigation to an area of interest. An inner ...


8
Gregg S Sutton, Brian T McMahon: Optical biopsy forceps. SpectraScience, Schwegman Lundberg Woessner & Kluth P A, June 9, 1998: US05762613 (66 worldwide citation)

An integrated optical biopsy forceps device and a method for tissue identification by optical analysis and biopsy sampling at a site within the body. The device includes an elongated catheter body for introduction into the body and navigation to an area of interest. An optical fiber extends through ...


9
Sutton Gregg S, Mcmahon Brian T: Optical biopsy forceps. Spectrascience, April 28, 1999: EP0910284-A1 (11 worldwide citation)

An integrated optical biopsy forceps device and a method for tissue identification by optical analysis and biopsy sampling at a site within the body. The device includes an elongated catheter body for introduction into the body and navigation to an area of interest. An optical fiber extends through ...


10
Mcmahon Brian T, Sievert Chester E Jr, Wilson Scott R, Zimmermann Ronald R, Palme Robert A, Yager John G, Walsh David R: Optical biopsy system and methods for tissue diagnosis. Spectrascience, VIKSNINS Ann S, September 16, 1999: WO/1999/045838 (5 worldwide citation)

A system characterized tissue using fluorescence spectroscopy, such as light-induced fluorescence. Native fluorescence ('autofluorescence') from endogenous tissue without requiring fluorescence-enhancing agents is used to distinguish between normal tissue, hyperplastic tissue, adenomatous tissue, an ...