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Smith Gary Keith, Duch David Stanley, Ferone Robert, Koch Arthur: Novel combination of benzoquinazoline antifolates and protecting agents. The Wellcome Foundation, Smith Gary Keith, Duch David Stanley, Ferone Robert, Koch Arthur, ROLLINS Anthony John, July 7, 1994: WO/1994/014448

The use of a protecting agent, for example a folate derivative such as folic acid or leucovorin, in combination with a non-competitive folic acid analogue, for example benzoquinazoline derivatives, for use in reducing the side effects associated with the administration of such non-competitive folic ...


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Smith Gary Keith: Bunyaviridal reaper proteins and uses therefor. Glaxo Group, Smith Gary Keith, LEVY David J, August 30, 2001: WO/2001/062936

Viral proteins with sequence and functional similarity to the drosophila cell death protein known as Reaper are provided. Reaper plays an important role in the apoptotic pathway. Methods using the viral proteins and nucleotides encoding such proteins are described.


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Smith Gary Keith, Blumenkopf Todd Andrew, Cory Michael: Therapy. The Wellcome Foundation, Smith Gary Keith, Blumenkopf Todd Andrew, Cory Michael, STOTT Michael John, May 18, 1995: WO/1995/013095

The present invention relates to improvements in targetted enzyme prodrug therapy including antibody-directed enzyme prodrug therapy (ADEPT), it particularly relates to novel enzymes and prodrugs for use in ADEPT.