1
Francis Barany, Jianzhao Liu, Brian W Kirk, Monib Zirvi, Norman P Gerry, Philip B Paty: Accelerating identification of single nucleotide polymorphisms and alignment of clones in genomic sequencing. Cornell Research Foundation, Sloan Kettering Institute for Cancer Research, Nixon Peabody, March 18, 2003: US06534293 (119 worldwide citation)

The present invention is directed to a method of assembling genomic maps of an organism's DNA or portions thereof. A library of an organism's DNA is provided where the individual genomic segments or sequences are found on more than one clone in the library. Representations of the genome ar ...


2
Ron S Israeli, Warren D W Heston, William R Fair: Prostate-specific membrane antigen. Sloan Kettering Institute For Cancer Research, John P White, July 23, 1996: US05538866 (97 worldwide citation)

This invention provides an isolated mammalian nucleic acid molecule encoding a mammalian prostate-specific membrane antigen. This invention also provides prostate-specific membrane nucleic acid of at least 15 nucleotides capable of specifically hybridizing with a sequence of a nucleic acid molecule ...


3
Ronald Breslow, Paul A Marks, Richard A Rifkind: Potent inducers of terminal differentiation and method of use thereof. Sloan Kettering Institute for Cancer Research, John P White, December 23, 1997: US05700811 (91 worldwide citation)

This invention is directed to compounds having the structure: ##STR1## wherein R.sub.1 and R.sub.2 are independently the same as or different from each other; when R.sub.1 and R.sub.2 are the same, each is a substituted or unsubstituted arylamino, cycloalkylamino, pyridineamino, piperidino, 9-purine ...


4
Bruce A White, F Carter Bancroft: Method for simple analysis of relative nucleic acid levels in multiple small samples by cytoplasmic dot hybridization. Sloan Kettering Institute for Cancer Research, John P White, June 30, 1987: US04677054 (90 worldwide citation)

A simple technique for the simultaneous measurement of relative levels of a specific mRNA in numberous small samples of biological specimens is described. The technique involves denaturation of cytoplasmic preparations, followed by dotting of up to 96 samples onto a single sheet of nitrocellulose, h ...


5
Ronald Breslow, Paul A Marks, Richard A Rifkind, Branko Jursic: Potent inducers of terminal differentiation and methods of use thereof. Sloan Kettering Institute for Cancer Research, The Trustees of Columbia, John P White, November 29, 1994: US05369108 (89 worldwide citation)

The present invention provides the compound having the structure: ##STR1## wherein each of R.sub.1 and R.sub.2 are independently the same as or different from each other; when R.sub.1 and R.sub.2 are the same, each is a substituted or unsubstituted arylamino, cycloalkylamino, pyridineamino, piperidi ...


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Stewart Shuman: Method for molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase. Sloan Kettering Institute for Cancer Research, John P White, June 16, 1998: US05766891 (72 worldwide citation)

This invention provides a modified vaccinia topoisomerase enzyme containing an affinity tag which is capable of facilitating purification of protein-DNA complexes away from unbound DNA. This invention further provides a modified sequence specific topoisomerase enzyme. This invention provides a metho ...


8
Carlos Lopez, Kyoichi A Watanabe, Uri Reichman, Jack J Fox: 5-Substituted 1-(2-Deoxy-2-substituted-.beta.-D-arabinofuranosyl)pyrimidine nucleosides. Sloan Kettering Institute for Cancer Research, Sprung Felfe Horn Lynch & Kramer, July 8, 1980: US04211773 (67 worldwide citation)

Pyrimidine nucleosides exhibiting anti-viral and anti-tumor effects have the formula ##STR1## wherein A is OR.sup.3, SR.sup.3, NR.sup.3 R.sup.4 or NHacyl wherein R.sup.3 and R.sup.4 are the same or different and are hydrogen, lower alkyl of 1 to 7 carbon atoms, aralkyl, or aryl;


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Elaine L Wilson, Janice Gabrilove: Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors. New York University, Sloan Kettering Institute For Cancer Research, Browdy and Neimark, March 18, 1997: US05612211 (65 worldwide citation)

Fibroblast growth factors are used in vivo, in situ and in vitro to stimulate stem cells, hemopoiesis, the immune system, transplant donor cells, culture and/or engraftment, wherein the use of fibroblast growth factors is disclosed for the stimulation of stem cells or hemopoietic cells, supporting c ...