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Bajji Ashok C, Kim Se Ho, Markovitz Benjamin, Trovato Richard, Tangallapally Rajendra, Anderson Mark B, Wettstein Daniel, Shenderovich Mark, Vanecko John A: Therapeutic compounds and their use in cancer. Myriad Genetics, Bajji Ashok C, Kim Se Ho, Markovitz Benjamin, Trovato Richard, Tangallapally Rajendra, Anderson Mark B, Wettstein Daniel, Shenderovich Mark, Vanecko John A, BAKER Jonathan A, November 22, 2007: WO/2007/134298 (10 worldwide citation)

Compounds of the formula (I) (II) (III) in which A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carbocyclic group! B is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carbocyclic group Rl is chosen from hydro, alkyl, aryl, heteroaryl ...


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Cheruvallath Zacharia, Semple Joseph, Rajappan Vasanthakumar, Rideout Darryl, Yalamoori Venkatachalapathi, Tsai Chung, Wu Feiyu, Thoresen Lars, Shenderovich Mark: 2-imidazolone and 2-imidazolidinone heterocyclic inhibitors of tyrosine phosphatases. Cengent Therapeutics, Cheruvallath Zacharia, Semple Joseph, Rajappan Vasanthakumar, Rideout Darryl, Yalamoori Venkatachalapathi, Tsai Chung, Wu Feiyu, Thoresen Lars, Shenderovich Mark, RIEGER Dale, July 27, 2006: WO/2006/078698 (6 worldwide citation)

Compounds and compositions are provided for modulating the activity of protein tyrosine phosphatases. The compounds for use in the compositions and methods provided herein have formulae (I) Protein tyrosine hosaphatase, including PTB-1B, mediated diseases and disorders include diabetes including Typ ...


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KUMAR Dange Vijay, SLATTUM Paul M, YAGER Kraig M, SHENDEROVICH Mark D, TANGALLAPALLY Rajendra, KIM Se Ho: COMPOSÉS ET SES UTILISATIONS THÉRAPEUTIQUES, COMPOUNDS AND THERAPEUTIC USES THEREOF. MYREXIS, KUMAR Dange Vijay, SLATTUM Paul M, YAGER Kraig M, SHENDEROVICH Mark D, TANGALLAPALLY Rajendra, KIM Se Ho, LAURENCE Kevin B, December 27, 2012: WO/2012/177782 (5 worldwide citation)

The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and complications associated with these diseases and disorders.


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