1
David H Mitchell, Ralph M Mitchell: Measurement of ligand/anti-ligand interactions using bulk conductance. Sensor Diagnostics, Gregory D Williams, David G Conlin, December 15, 1987: US04713347 (194 worldwide citation)

Methods, apparatus and sensors are described for detection of specific ligands in a fluid sample by measuring ligand-specific changes in the bulk electrical conductance (or resistance) of a fixed test volume, with antiligand or ligand localized in or near that volume.


2
Mitchell David H, Mitchell Ralph M: Measurement of ligand/anti-ligand interactions using bulk conductance.. Sensor Diagnostics, February 4, 1987: EP0210224-A1

A method and apparatus for determining the presence of a ligand in a fluid sample comprising exposing the fluid sample in a test cell (103) and a control cell (111). Each cell comprises (respectively) a predetermined region containing immobilized anti-ligand that is exposed to the fluid sample flow ...


3
Mitchell David H, Mitchell Ralph M: Mesure des interactions ligand/anti-ligand grace a la conductance interne, Measurement of ligand/anti-ligand interactions using bulk conductance. Sensor Diagnostics, RIDOUT & MAYBEE, January 17, 1989: CA1249026

ABSTRACT OF THE INVENTION Methods, apparatus and sensors are described for detection ofspecific ligands in a fluid sample by measuring ligand-specificchanges in the bulk electrical conductance (or resistance) of afixed test volume, with antiligand or ligand localized in or nearthat volume. -149-


4
Mitchell David H, Mitchell Ralph M: Measurement of ligand/anti-ligand interactions using bulk conductance. Sensor Diagnostics, CONLIN David G, July 17, 1986: WO/1986/004147

A method and apparatus for determining the presence of a ligand in a fluid sample comprising exposing the fluid sample in a test cell (103) and a control cell (111). Each cell comprises (respectively) a predetermined region containing immobilized anti-ligand that is exposed to the fluid sample flow ...